Through seven editions, Protocols for High-Risk Pregnancies has helped busy obstetricians keep pace with a constantly evolving field. Providing just-in-time content, its focus on protocols and guidelines helps organize medical thinking, avoid heuristic errors of omission and commission, and optimize maternal and fetal outcomes.

As with the prior six editions, the editors have once again assembled some of the world’s top obstetrical and medical experts. This seventh edition has also been expanded to include a number of new topics, including:

Protocols on opioid use, misuse and addition in pregnancy and postpartum
Noninvasive prenatal diagnosis of aneuploidy
Periconceptual genetic screening
Expanded protocols on maternal valvular heart disease and cardiomyopathies
Protocols on arboviruses, including Zika and malaria

Protocols for High-Risk Pregnancies: An Evidence-Based Approach will be an essential reference for obstetricians, medical students, general practitioners and all medical professionals who are seeking the most up-to-date information and guidance on high-risk pregnancies.

About the Editors

JOHN T. QUEENAN, MD, Professor and Chairman Emeritus, Department of Obstetrics and Gynecology, Georgetown University School of Medicine, Washington, DC, USA.

CATHERINE Y. SPONG, MD, is a Professor and Vice Chair in the Department of Obstetrics and Gynecology at University of Texas Southwestern Medical Center, Dallas, TX, USA. She also serves as Chief of the Department's Division of Maternal-Fetal Medicine.

CHARLES J. LOCKWOOD, MD, MHCM, is Senior Vice President of USF Health, Dean of Morsani College of Medicine and a Professor of Obstetrics and Gynecology, and Public Health at the University of South Florida in Tampa, FL, USA.

Preface

List of contributors

Part 1 Concerns in Pregnancy

1) Alcohol use in pregnancy and lactation: (Ruta Nonacs – rnonacs@partners.org)

2) Smoking, vaping and nicotine exposure: (George Saade - gsaade@utmb.edu)

3) Opioid abuse: (Mishka Terplan - Mishka.Terplan@vcuhealth.org).

4) Depression and PTSD: (Kim Yonkers - kimberly.yonkers@yale.edu)

Part 2 Antenatal testing

5) Aneuploidy testing: (Mary Norton UCSF - Mary.Norton@ucsf.edu)

6) Fetal echocardiography: (Josh Copel -joshua.copel@yale.edu)

7) Doppler velocimetry: (Henry Galan - henry.galan@ucdenver.edu)

8) Antepartum Testing: (Mike Nageotte - MNageotte@memorialcare.org)

9) Fetal Transfusion: Patricia Santiago (Patricia.santiago@utsouthwestern.edu)

10) Preconception genetic screening jeffrey.kuller@duke.edu with co-author Lauren Sayres - lauren.sayres@duke.edu

Part 3 Maternal Disease

11) Maternal Anemia: Elaine Duryea Elaine.duryea@utsouthwestern.edu

12) Hemoglobinopathies: (Judette Louis - jlouis1@health.usf.edu)

13) Alloimmune Thrombocytopenia: Dick Berkowitz - rb2212@columbia.edu and Russell Miller rsm20@cumc.columbia.edu)

14) Autoimmune Disease Lisa Sammaritano at HSS - SammaritanoL@HSS.EDU and Bonnie Bermas at UT SW - Bonnie.Bermas@utsouthwestern.edu

15) Antiphospholipid antibody syndrome: Bob Silver bsilver@hsc.utah.edu

16) Inherited Thrombophilias: (Andra James - andra.james@duke.edu)

17) Valvular heart disease: (Dr. Afshan Hameed - ahameed@uci.edu )

18) Cardiomyopathy: (cmzelop@comcast.net+Sarah Easter SEASTER@BWH.HARVARD.EDU

19) Thromboembolism: (Mike Paidas - mxp1440@med.miami.edu

20) Renal Disease: Shivani Patel Shivani.Patel@UTSouthwestern.edu

21) Obesity: Patrick Ramsey at UT San Antonio RamseyP@uthscsa.edu

22) Diabetes: Mark.Landon@osumc.edu and Steve Gabbe- Steven.Gabbe@osumc.edu

23) Thyroid Disorders: (Steve Thung – and Elizabeth O. Buschur MDStephen.Thung@osumc.edu Elizabeth.buschur@osumc.edu)

24) Hepatitis: (John Sinnott - jsinnott@health.usf.edu and Christian Brechot - cbrechot@health.usf.edu)

25) Asthma: (Michael Schatz at UCSD michael.x.schatz@kp.org

26) Epilepsy: (Tom McElrath at Brigham & Women’s tmcelrath@bwh.harvard.edu

27) Chronic HypertensionBaha.M.Sibai@uth.tmc.edu : Baha Sibai - Baha.M.Sibai@uth.tmc.edu)

28) Congenital infections: CMV, Toxo, Herpes and Rubella: (Brenna Hughes - brenna.hughes@duke.edu

29) Syphilis: (Emily Adhikari at UTSW – Emily.Adhikari@UTSouthwestern.edu

30) Arboviruses: Zika, West Nile and Chagas: (Karin Nielsen-Saines - knielsen@mednet.ucla.edu

31) Influenza and TB: (Amanda Zofkie and Vanessa Rogers Amanda.Zofkie@UTSouthwestern.edu and Vanessa.rogers@utsouthwestern.edu)

32) Malaria: (Blair Wylie - bwylie@bidmc.harvard.edu)

33) HIV: (Emily Adahkari Emily.Adhikari@UTSouthwestern.edu

34) Parvovirus B19: Laura Reily lar9110@med.cornell.edu and Emilie Vander Haar elv9025@med.cornell.edu

35) Group B Streptococcus: ()Mara Dinsmoor - mdinsmoor@northshore.org and Dr. Caitlin MacGregor - CMacgregor@northshore.org

36) Gallbladder, Fatty Liver and Pancreatic Disease: Vic Velanovich, MD Stephanie Ros Elizabeth Hoover

vvelanov@health.usf.edu sros@health.usf.edu

Part 4 Obstetric Problems

37) Cervical Insufficiency: (Vincenzo Berghella - Vincenzo.berghella@jefferson.edu and Rupsa Boelig (Rupsa.c@gmail.com)

38) Nausea and Vomiting: (Haywood Brown - haywoodb@health.usf.edu

39) Fetal Death: Bob Silver bsilver@hsc.utah.edu

40) Disorders of Amniotic Fluid Volume: Heather Lipkindheather.lipkind@yale.edu>

41) Fetal Growth Restriction: Jodi Dashe Jodi.dashe@utsouthwestern.edu

42) Rh and other alloimmunizations: Ken Moise Kenneth.J.Moise@uth.tmc.edu

43) Preterm Labor: (Hy Simhan - hsimhan@mail.magee.edu)

44) Prevention of Preterm Birth: Stock STOCK Sarah <Sarah.Stock@ed.ac.uk>

45) Premature Rupture of the Membranes: (Brian Mercer - bmercer@metrohealth.org)

46) Late-Preterm and Early-Term Deliveries: (Catherine.spong@utsouthwestern.edu)

47) Chorioamnionitis: (Catalin Buhimschi - csb01@uic.edu)

48) Third Trimester Bleeding: (Christina Han - CSHan@mednet.ucla.edu)

49) Amniotic Fluid Embolism: (Mike Belfort - belfort@bcm.edu)

50) Preeclampsia Baha Sibai - Baha.M.Sibai@uth.tmc.edu

Part 5 Labor and Delivery

51) Induction of Labor: (Rachel Sinkey - rachel.sinkey@gmail.com)

52) Intrapartum fetal heart rate monitoring: (David A. Miller – dmiller@usc.edu)

53) Breech Delivery: (Justus Hofmeyr - justhof@gmail.com)

54) VBAC: (Jim Scott - james.scott@hsc.utah.edu)

55) Placenta Accreta: (Deirdre Lyell at Stanford (djlyell@gmail.com)

56) Shoulder Dystocia: (George Macones - George.Macones@austin.utexas.edu and Robert Gherman ghermdoc@gmail.com)

57) Twins, Triplets and Beyond: (Mary D’Alton - md511@cumc.columbia.edu)

58) Postpartum Hemorrhage (DavidB.Nelson@UTSouthwestern.edu

59) Appendix A – Evaluation of Fetal Health and Defects: (Lynn Simpson - ls731@columbia.edu)

Index

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