Quinones and Quinone Enzymes, Part B

by Sies; Packer

• ISBN13: 9780121827861
• ISBN10: 0121827860
• Edition: 1st
• Format: Hardcover
• Copyright: 2004-02-20
• Publisher: Elsevier Science

Summary

Quinones are members of a class of aromatic compounds with two oxygen atoms bonded to the ring as carbonyl groups. This volume covers the role of quinines enzymes in cellular signalling and modulation of gene expression.

Table of Contents

CONTRIBUTORS TO VOLUME 382	xi
PREFACE	xv
VOLUMES IN SERIES	xvii
Section I. Mitochondrial Ubiquinone and Reductases
1. Mitochondrial Quinone Reductases: Complex I
GIORGIO LENAZ, ROMANA FATO, ALESSANDRA BARACCA, AND MARIA LUISA GENOVA	3	(18)
2. Q-cycle Bypass Reactions at the Q0 Site of the Cytochrome bc1 (and Related) Complexes
DAVID M. KRAMER, ARTHUR G. ROBERTS, FLORIAN MULLER, JONATHAN CAPE, AND MICHAEL K. BOWMAN	21	(24)
3. Targeting Coenzyme Q Derivatives to Mitochondria
ROBIN A. J. SMITH, GEOFFREY F. KELSO, ANDREW M. JAMES, AND MICHAEL P. MURPHY	45	(22)
4. The Mitochondrial Interplay of Ubiquinol and Nitric Oxide in Endotoxemia
CONSTANZA L. LISDERO, MARIA CECILIA CARRERAS, ALAIN MEULEMANS, MARIANA MELANI, MICHEL AUBIER, JORGE BOCZKOWSKI, AND JUAN JOSE PODEROSO	67	(14)
5. Mitochondrial Respiratory Chain Dysfunction Caused by Coenzyme Q Deficiency
PIERRE RUSTIN, ARNOLD MUNNICH, AND AGNES RÖTIG	81	(8)
6. Coenzyme Q Cytoprotective Mechanisms
TOM S. CHAN, JOHN X. WILSON, AND PETER J. O'BRIEN	89	(16)
7. Dietary Coenzyme Q10 and Mitochondrial Status
CHING KUANG CHOW	105	(10)
Section II. Anticancer Quinones and Quinone Oxidoreductases
8. NAD(P)H: Quinone Oxidoreductase 1 (NQO1, DT-Diaphorase), Functions and Pharmacogenetics
DAVID ROSS AND DAVID SIEGEL	115	(29)
9. Structure and Mechanism of NAD[P]H: Quinone Acceptor Oxidoreductases (NQO)
MARIO A. BIANCHET,MARGARITA FAIG, AND L. MARIO AMZEL	144	(30)
10. Diaziridinylbenzoquinones
ANGELA DI FRANCESCO, TIMOTHY H. WARD, AND JOHN BUTLER	174	(20)
11. Quinone Reductase-Mediated Nitro-Reduction: Clinical Applications
RICHARD J. KNOX AND SHIUAN CHEN	194	(27)
12. Bioactivation and Resistance to Mitomycin C
HELEN A. SEOW, PHILIP G. PENKETH, RAYMOND P. BAUMANN, AND ALAN C. SARTORELLI	221	(13)
13. NAD(P)H:Quinone Oxidoreductase 1 Expression, Hydrogen Peroxide Levels, and Growth Phase in HeLa Cells
ROSARIO I. BELLO, CONSUELO GOMEZ-DIAZ, PLÁCIDO NAVAS, AND JOSÈ M. VILLALBA	234	(9)
14. The "Prochaska" Microtiter Plate Bioassay for Inducers of NQO1
JED W. FAHEY, ALBENA T. DINKOVA-KOSTOVA, KATHERINE K. STEPHENSON, AND PAUL TALALAY	243	(15)
15. Structure-Activity Relationships in Two-Electron Reduction of Quinones
NARIMANTAS CENAS, ZILVINAS ANUSEVICIUS, HENRIKAS NIVINSKAS, LINA MISEVICIENE, AND JONAS SARLAUSKAS	258	(20)
16. p53-Dependent Apoptosis and NAD(P)H:Quinone Oxidoreductase 1
GAD ASHER, JOSEPH LOTEM, LEO SACHS, AND YOSEF SHAUL	278	(15)
17. The Role of Endogenous Catechol Quinones in the Initiation of Cancer and Neurodegenerative Diseases
ERCOLE CAVALIERI, ELEANOR ROGAN, AND DHRUBAJYOTI CHAKRAVARTI	293	(27)
18. Induction of NQO1 in Cancer Cells
ASHER BEGLEITER AND JEANNE FOURIE	320	(35)
Section III. Quinone Reductases: Chemoprevention and Nutrition
19. Role of Nicotinamide Quinone Oxidoreductase 1 (NQO1) in Protection Against Toxicity of Electrophiles and Reactive Oxygen Intermediates
PAUL TALALAY AND ALBENA T. DINKOVA-KOSTOVA	355	(9)
20. Activation and Detoxification of Naphthoquinones by NAD(P)H:Quinone Oxidoreductase
REX MUNDAV	364	(16)
21. Induction of Quinone Reductase as a Primary Screen for Natural Product Anticarcinogens
YOUNG-HWA KANG AND JOHN M. PEZZUTO	380	(34)
22. Chemoprevention by 1,2-Dithiole-3-Thiones Through Induction of NQO1 and Other Phase 2 Enzymes
MI-KYOUNG KWAK, MINERVA RAMOS-GOMEZ, NOBUNAO WAKABAYASHI, AND THOMAS W. KENSLER	414	(9)
23. Chemical Structures of Inducers of Nicotinamide Quinone Oxidoreductase 1 (NQO1)
ALBENA T.KINKOVA-KOSTOVA, JED W. FAHAEY, AND PAUL TALALAY	423	(26)
24. Induction of Phase II Enzymes by Aliphatic Sulfides Derived from Garlic and Onions: An Overview
REX MUNDAY AND CHRISTINE M. MUNDAY	449	(8)
25. Upregulation of Quinone Reductase by Glucosinolate Hydrolysis Products from Dietary Broccoli
ELIZABETH H. JEFFERY AND KRISTIN E. STEWART	457	(16)
Section IV. Quinones and Age-Related Diseases
26. Therapeutic Effects of Coenzyme Q10 in Neurodegenerative Diseases
M. FLINT BEAL	473	(15)
27. Neuroprotective Actions of Coenzyme Q10 in Parkinson's Disease
S. SHARMA, M. KHERADPEZHOU, S. SHAVALI, H. EL REFAEY, J. EKEN, C. HAGEN, AND M. EBADI	488	(23)
AUTHOR INDEX	511	(50)
SUBJECT INDEX	561