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9781607611851

Renin Angiotensin System and Cardiovascular Disease

by ;
  • ISBN13:

    9781607611851

  • ISBN10:

    1607611856

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2009-09-04
  • Publisher: Humana Pr Inc

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Summary

The renin angiotensin system plays an essential role on cardiac and vascular functions and their connection in the generation of cardiovascular diseases. Renin Angiotensin System and Cardiovascular Disease covers indispensable aspects such as intracellular signaling, regulation of cell volume in the failing heart, the presence of an intracrine renin angiotensin system, and the influence of prorenin/renin, angiotensin II, angiotensin (1-7) and aldosterone. Furthermore, the role of the mineralocorticoid receptor as an imperative component of the intracrine renin angiotensin system and as a regulator of extracellular action of angiotensin II is described, reinforcing the view that aldosterone inhibitors are helpful in the treatment of heart failure and hypertension. Renin Angiotensin System and Cardiovascular Disease provides readers with an outstanding review of the major topics involving the renin angiotensin system and cardiovascular disease. With contributions by an international panel of experts, Renin Angiotensin System and Cardiovascular Disease presents the most relevant aspects of the role of the renin angiotensin aldosterone system on cardiovascular diseases including hypertension, congestive heart failure, atherosclerosis and diabetes. The volume Editors, Dr. Walmor C. DeMello and Dr. Edward Frohlich, both established specialists in their respective fields, team up to discuss a range of topics from Renin Angiotensin Aldosterone System and Pathobiology of Hypertension to Inhibiting the Renin Angiotensin Aldosterone System in Patients with Heart Failure and Myocardial Infarction.

Table of Contents

Systemic Versus Local Renin Angiotensin Systems: An Overviewp. 1
Clinical Import of the Local Renin Angiotensin Aldosterone Systemsp. 7
Renin, Prorenin, and the (Pro)Renin Receptorp. 15
Local Renin Angiotensin Systems in the Cardiovascular Systemp. 25
Renin-Angiotensin-Aldosterone System and Pathobiology of Hypertensionp. 35
AT1 Receptors, Angiotensin Receptor Blockade, and Clinical Hypertensive Diseasep. 59
Structural and Electrophysiological Remodeling of the Failing Heartp. 81
Inhibiting the Renin Angiotensin Aldosterone System in Patients with Heart Failure and Myocardial Infarctionp. 93
Left Ventricular Hypertrophy and Treatment with Renin Angiotensin System Inhibitionp. 103
Angiotensin-(l-7), Angiotensin-Converting Enzyme 2, and New Components of the Renin Angiotensin Systemp. 121
Kinin Receptors and ACE Inhibitors: An Interrelationshipp. 135
Kinins and Cardiovascular Diseasep. 151
CMS and T??? 2 Diabetes Mellitus: Bound Together by the Renin Angiotensin Aldosterone Systemp. 187
Renin Angiotensin Aldosterone System and Cardiovascular Diseasep. 207
Renin Angiotensin System and Atherosclerosisp. 215
Renin Angiotensin System and Agingp. 231
Subject Indexp. 245
Table of Contents provided by Ingram. All Rights Reserved.

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