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9780813817989

Schalm's Veterinary Hematology

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  • ISBN13:

    9780813817989

  • ISBN10:

    0813817986

  • Edition: 6th
  • Format: Hardcover
  • Copyright: 2010-07-13
  • Publisher: Wiley-Blackwell
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List Price: $318.95

Summary

The long-awaited Sixth Edition of Schalm's Veterinary Hematology has been revised and reorganized to increase accessibility and cohesiveness of the text. Topics are grouped within established disciplines in hematology, and outlines are now included at the beginning of each chapter. The book features new sections on Hematotoxicity and Quality Control and Laboratory Techniques, and includes expanded sections on Laboratory Animal Hematology, Species Specific Hematology, and Hematologic Neoplasia. With in-depth coverage on all aspects of the field, this comprehensive reference is an essential purchase for veterinary clinical hematologists, internists, and students.

Author Biography

Douglas J. Weiss, DVM, MS, PhD, is Professor of Veterinary and Biomedical Sciences at the University of Minnesota in St. Paul. Current areas of research include immune mechanisms that determine susceptibility/resistance to Johne's disease, detection and differentiation of leukemias and lymphomas, and detection of activated neutrophils and platelets in infectious diseases.

K. Jane Wardrop, DVM, MS, DACVP, is Professor Chief, Clinical Pathology at Washington State University's Department of Veterinary Clinical Sciences. Specific research areas include veterinary transfusion medicine, hemostasis, and thrombosis. She was also an editor on the Fifth Edition of Schalm's.

Table of Contents

Hematopoiesis
Embryonic and Fetal Hematopoiesis
Structure of Bone Marrow
Stem Cell Biology
Cluster of Differentiation (CD) Antigens
The Hematopoietic System
Erythropoiesis
Granulopoiesis
Monocyte and Dendritic Cell Production and Distribution
Thrombopoiesis
Lymphopoiesis
Vasculogenesis/Endothelial Progenitor Cells
Hematotoxicity
Design and Methods Used for Preclinical Hematotoxicity Studies
Interpretation of Hematology Data in Preclinical Toxicological Studies
Preclinical Evaluation of Compound-Related Cytopenias
Preclinical Evaluation of Compound-Related Alterations in Hemostasis.
Drug-induced Blood Cell Disorders
Myelonecrosis and Acute Inflammation
Chronic Inflammation and Secondary Myelofibrosis
Infectious Injury to Bone Marrow
Erythrocytes
Erythrocyte Structure and Function
Erythrocyte Biochemistry
Erythrokinetics and Erythrocyte Destruction
Erythrocyte Morphology
Laboratory and Clinical Diagnosis of Anemia
Polycythemia
Iron and Copper Deficiency and Disorder of Iron Metabolism
The Prophyrias and Prophyrinurias
Erythrocyte Enzyme Abnormalities
Erythrocyte Membrane Defects
Congenital Dyserythropoiesis
Anemias Caused by Rickettsia and Protozoa
Anemia Associated with Bacteria and Viral Infections
Immune-mediated Anemia in the Dog
Immune-mediated Anemia in the Cat
Immune-mediated Anemias in Ruminants and Horses
Anemias Associated with Oxidative Injury
Anemia of Inflammatory, Neoplastic, Renal, and Endocrine Diseases
Pure Red Cell Aplasia
Aplastic Anemia
Leukocytes
Neutrophil Structure and Biochemistry
Neutrophil Distribution and Function
Neutrophil Function Disorders
Eosinophils and their Disorders
Basophils, Mast Cells and Their Disorders
Monocytes and Macrophages and Their Disorders
Interpretation of Ruminant Leukocyte Responses
Interpretation of Equine Leukocyte Responses
Interpretation of Canine Leukocyte Responses
Interpretation of Feline Leukocyte Responses
Determination and Interpretation of the Avian Leukogram
Biology of Lymphocytes and Plasma Cells
Structure, Function, and Disorders of Lymphoid Tissue
Disorders of the Spleen
Systemic Lupus Erythematosus
Feline Immunodeficiency Virus
T cell, Immunoglobulin, and Complement Immunodeficiency Disorders
Severe Combined Immunodeficiencies
Benign Lymphadenopathies
Hematologic Neoplasia
Cell Cycle Control in Hematopoietic Cells
Epidemiology of Hematopoietic Neoplasia
Genetics of Hematopoietic Neoplasia
Transforming Retroviruses
Bone Marrow-derived Sarcomas
Classification of Lymphoma and Leukemia
General Features of Leukemia and Lymphoma
Myelodysplastic Syndromes
Acute Myeloid Leukemia
Mast Cell Cancer
B-cell Tumors
Plasma Cell Tumors
Hodgkins Lymphoma
T cell Lymphoproliferative Diseases
Histiocytic Proliferative Diseases
Gene Therapy
Platelets
Platelet Structure
Platelet Biochemistry Signal Transduction and Function
Platelet Kinetics and Laboratory Evaluation of Thrombocytopenia
Immune-mediated Thrombocytopenia
Non-immune-mediated Thrombocytopenia
Essential Thrombocythemia and Reactive Thrombocytosis
von Willebrand Disease
Inherited Intrinsic Platelet Disorders
Acquired Platelet Dysfunction
Hemostasis
Overview of Hemostasis
Acquired Coagulopathies
Hereditary Coagulopathies
Thrombotic Disorders
Disseminated Intravascular Coagulation
Vascular Diseases
Treatment of Hemostatic Defects
Overview of Avian Hemostasis: 16 pages
Transfusion Medicine
Erythrocyte Antigens and Blood Groups
Granulocyte and Platelet Antigens
Principles of Canine and Feline Blood Collection, Processing, and Storage
Red Blood Cell Transfusion in the Dog and Cat
Transfusion of Plasma Products
Platelet and Granulocyte Transfusion
Blood Transfusion in Large Animals
Blood Transfusion in Exotic Species
Transfusion Reactions
Major Histocompatability Complex Antigens
Hematopoietic Stem Cell Transplantation
Clinical Use of Hemopoietic Growth Factors
Species Specific Hematology
Normal Hematology of the Dog
Normal Hematology of the Cat
Normal Hematology of the Horse
Normal Hematology of Cattle
Normal Hematology of Sheep, and Goats
Normal Hematology of the Pig
Hematology of Laboratory Animals
Hematology of Ferrets
Hematology of Guinea Pigs
Hematology of the Mongolian Gerbil
Hematology of the Syrian (Golden) Hamster
Hematology of Camelids
Hematology of Cervids
Hematology of Water Buffalo
Hematology of the American Bison
Hematology of Reindeer
Hematology of Elephants
Hematology of Marine Mammals
Hematology of Chickens and Turkeys
Hematology of Psittacines
Hematology of Waterfowl and Raptors
Hematology of Ratites
Hematology of Fish
Hematology of Reptiles
Hematology of Elasmobranchs
Quality Control and Laboratory Techniques
Quality Control
Diagnostic Test Validation
Reference Intervals
Evaluation of Bone Marrow
Assays for Hematopoietic Precursor Cells
Radiolabeling and Scintigraphic Imaging of Platelets and Leukocytes
Automated Hematology Systems
Reticulocyte and Heinz Body Staining and Enumeration
Flow Cytometry
Laboratory Testing of Coagulation Disorders: 44 pages
Clinical Blood Typing and Crossmatching
Testing for Immune-mediated Hematologic Disease
Evaluation of Neutrophil Function
Evaluation of Platelet Function
Immunophenotyping and Determination of Clonality
Cytochemical Staining
Electrophoresis and Acute Phase Protein Measurement
Measurement of Serum Iron Concentration, TIBC, and Serum Ferritin Concentration
Molecular Techniques and Real time-PCR
Genetic Evaluation of Inherited and Acquired Hematologic Disease
Table of Contents provided by Publisher. All Rights Reserved.

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