Schizophrenia, 2nd Edition

by Editor: Steven R. Hirsch (Charing Cross and Westminster Medical School); Editor: Daniel R. Weinberger (MD)

• ISBN13: 9781405140102
• ISBN10: 1405140100
• Edition: 2nd
• Format: eBook
• Copyright: 2008-06-01
• Publisher: Wiley-Blackwell

Summary

Schizophrenia is one of the most complex and puzzling diseases to affect mankind. It is the most common of the severe mental illnesses (psychoses) with an estimated prevalence of 0.5 - 1% in the general population and accounts for a very large portion of the day to day workload of the average psychiatrist. 50% of long-term psychiatric patients in mental hospitals are schizophrenic.There is a great deal of controversy about the causes, diagnosis and treatment of schizophrenia with the consequence that a huge amount of research is carried out in the field by psychiatrists, psychologists, neuroscientists and pharmacologists. For the average practising psychiatrist seeing schizophrenics on a regular basis, making sense of the vast body of information on the subject and filtering out what is of clinical relevance can be very difficult. There is a constant stream of new drugs emerging and the newer generation of drugs (the so-called atypicals) is very effective, but often expensive.The Editors (one American and one British) are both highly respected clinical psychiatrists who are probably the leading experts on schizophrenia from their respective countries and jointly have published almost 150 papers on the subject. They have brought together a strong group of contributors from the USA, UK and Europe to produce what will be an essential reference for the trainee and practising psychiatrist.The book consists of four sections; descriptive aspects, causative aspects, physical treatments and psychological/behavioural/social treatments. There will be discussion of the theoretical controversies over symptomatology, classification and aetiology, the relationship of schizophrenia to the other psychoses, the significance of positive and negative symptoms and pre-morbid personality. There will be chapters on organic models of schiziophrenia, neurodevelopmental, genetic and structural studies and the role of high-expressed emotion. The final section will cover social and environmental treatment, the role of the families of schizophrenics and the psychoanalytical therapies. There is a new chapter on the patient's perspective written by a former patient.

Table of Contents

Contributors

Foreword

Preface to the Second Edition

Preface to the First Edition

Descriptive Aspects

Concepts of Schizophrenia

Descriptive Psychopathology

Syndromes of Schizophrenia

Schizophrenia in Childhood

Atypical Psychotic Disorders

Late Life Schizophrenia

The Schizophrenia Spectrum Personality Disorders

Course and Outcome of Schizophrenia

Depression in Schizophrenia

Neurocognitive Deficits in Schizophrenia

Biological Aspects

The Secondary Schizophrenias

The Epidemiological Horizon

Factors Increasing the Risk for Schizophrenia

Genetics of Schizophrenia

Biology of Genetic Susceptibility

Electrophysiology

Neuropathology of Schizophrenia

Schizophrenia as a Neurodevelopmental Disorder

The Neurochemistry of Schizophrenia

The Dopamine Theory Revisited

Animal Neuropharmacology and its Predicition of Clinical Response

Brain Imaging

Physical Treatments

The Clinical Treatment of Schizophrenia with Antipsychotic edication

The Acute Treatment of Schizophrenia with Antipscyhotic Medication

Maintenance, Medication and Relapse Prevention

Treatment resistent Schizophrenia

Electroconvulsive Therapy in Schizophrenia

Neuroleptic-induced Acute Extrapyramidal Syndromes and Tardive Dyskinesia

Non-neurological Side Effects of Antipsychotic Agents

Social, Environmental and Psychosocial Aspects

Violence and Schizophrenia

Schizophrenia and Psychosocial Stresses

Psychiatric Rehabilitation and the Application of Cognitive Behavioural Therapies

Psychological Treatments and Therapies for Schizophrenia

Community Care

Patient's Perspective of Schizophrenia

Economics of Schizophrenia and its Treatment

Index

Table of Contents provided by Publisher. All Rights Reserved.