Schizophrenia From Neuroimaging to Neuroscience

by Lawrie, Stephen; Johnstone, Eve; Weinberger, Daniel

• ISBN13: 9780198525967
• ISBN10: 0198525966
• Format: Hardcover
• Copyright: 2005-01-27
• Publisher: Oxford University Press

Summary

Neuroimaging techniques have made a huge contribution to our understanding of schizophrenia and other neuropsychiatric disorders. Until now however, texts on both schizophrenia and neuroimaging have paid little attention to the overlap between these areas. This new volume is the firstdedicated to unravelling how these techniques can help us better understand this complex disorder. Each chapter focuses on a particular research method, describing the nature of the findings, the main technological problems, and future possibilities. Though including sufficient methodological detail to be of value to imaging researchers, the emphasis throughout is on providing information ofvalue to clinicians. Written and edited by leaders in schizophrenia research, this book details what structural and functional brain imaging studies have already established about schizophrenia and what developments are likely in the foreseeable future.

Table of Contents

Contributors	ix
Abbreviations	xiii
1 Early studies of brain anatomy in schizophrenia	1	(20)
Eve C. Johnstone and David G.C. Owens
2 Structural magnetic resonance imaging	21	(38)
Andrew McIntosh and Stephen M. Lawrie
3 Structural brain MRI studies in childhood-onset schizophrenia and childhood atypical psychosis	59	(14)
Nitin Gogtay, Alexandra Sporn, and Judith L. Rapoport
4 MR proton spectroscopy	73	(20)
Stefano Marenco, Daniel R. Weinberger, and Alessandro Bertolino
5 Diffusion tensor magnetic resonance imaging	93	(26)
Mark E. Bastin and Stephen M. Lawrie
6 Automated analysis of structural MRI data	119	(48)
Paul M. Thompson, Judith L. Rapoport, Tyrone D. Cannon, and Arthur W. Toga
7 Functional mapping with single-photon emission computed tomography and positron emission tomography	167	(46)
Andreas Heinz, Berenice Romero, and Daniel R. Weinberger
8 Neuroreceptor mapping with PET and SPECT	213	(24)
R.A. Bantick, A.J. Montgomery, and P.M. Grasby
9 Functional magnetic resonance imaging (fMRI)	237	(56)
Garry D. Honey, Phillip K. McGuire, and Edward T. Bullmore
10 Event related potentials	293	(38)
Margaret A. Niznikiewicz, Kevin M. Spencer, Dean F. Salisbury, and Robert W. McCarley
11 Magnetoencephalography	331	(18)
Timm Rosburg and Heinrich Sauer
12 Spatial analysis of ERP and EEG data	349	(14)
Werner K. Strik and Thomas Koenig
13 Towards an integrated imaging of schizophrenia	363	(34)
Stephen M. Lawrie, Eve C. Johnstone, and Daniel R Weinberger
Index	397