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Harry Guess is the editor of Science of the Placebo: Toward an Interdisciplinary Research Agenda, published by Wiley.
Linda Engel is the editor of Science of the Placebo: Toward an Interdisciplinary Research Agenda, published by Wiley.
Arthur Kleinman is the editor of Science of the Placebo: Toward an Interdisciplinary Research Agenda, published by Wiley.
John Kusek is the editor of Science of the Placebo: Toward an Interdisciplinary Research Agenda, published by Wiley.
Contributors | |
Foreword | |
An Overview | p. 1 |
Historical and ethical perspectives | p. 33 |
"Seeing" the placebo effect: historical legacies and present opportunities | p. 35 |
Ethical issues in use of placebo in medical practice and clinical trials | p. 53 |
Elucidating placebo effects: explanatory mechanisms | p. 75 |
Explanatory mechanisms for placebo effects: cultural influences and the meaning response | p. 77 |
Explanatory mechanisms for placebo effects: cognition, personality and social learning | p. 108 |
Explanatory mechanisms for placebo effects: Pavlovian conditioning | p. 133 |
Regression to the mean or placebo effect? | p. 158 |
Elucidating placebo effects: intervening psychophysiology | p. 167 |
Neuroendocrine mediators of placebo effects on immunity | p. 169 |
Endogenous opioid and non-opioid pathways as mediators of placebo analgesia | p. 183 |
Use of placebo groups in clinical trials - methodological and ethical issues | p. 207 |
Placebo controlled trials and active controlled trials: ethics and inference | p. 209 |
When is it appropriate to use a placebo arm in a trial? | p. 227 |
The pros and cons of non-inferiority (equivalence) trials | p. 236 |
Use of placebo in large-scale, pragmatic trials | p. 249 |
Placebo controls in clinical trials of new therapies for conditions for which there are known effective treatments | p. 264 |
Priorities for future research | p. 281 |
The research and ethical agenda | p. 283 |
Recommendations for research to further elucidate the nature of the placebo effect | p. 286 |
Recommendations for research on applying placebo effects in clinical practice | p. 293 |
Recommendations for research concerning the use of placebos in clinical trials to test pharmacological and procedural interventions | p. 300 |
Recommendations for research concerning the use of placebos in clinical trials to test behavioral interventions | p. 306 |
Conclusions and future directions | p. 311 |
Conclusions and future directions | p. 313 |
Appendix | p. 317 |
Index | p. 323 |
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