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9783540211587

The Living Brain and Alzheimer's Disease

by ; ; ; ;
  • ISBN13:

    9783540211587

  • ISBN10:

    3540211586

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2004-11-15
  • Publisher: Springer Verlag
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List Price: $99.00

Summary

From large cross-sectional studies of autopsy material, it seems as if a time course of Alzheimer's Disease, at least on average, can be mapped out: a pattern of hierarchical vulnerability for neuronal loss and neurofibrillary tangles beginning in medial temporal lobe structures proceeding through association areas. Plaques follow their own temporal course, with widespread cortical deposits occurring even early in a disease process. The whole process may well take twenty years, the first half of which may be without overt symptoms.

Table of Contents

Neuropathology of Alzheimer's disease, as Seen in Fixed Tissues
Charles Duyckaerts, Dominique Langui, Nadège Girardot, Jean-Jacques Hauw, Benoit Delatour
1(16)
Cerebrospinal Fluid Biomarkers for the Diagnosis of Alzheimer's Disease
Andreas Papassotiropoulos, Alessia Maddalena, Danielle Gretener, Roger M. Nitsch, Christoph Hock
17(8)
The Living Brain and Alzheimer's Disease
Bradley T. Hyman
25(8)
In Vivo Imaging of Alzheimer Pathology in Transgenic Mice Using Multiphoton Microscopy
Brian J. Bacskai, William E. Klunk, Gregory A. Hickey, Jesse Skoch, Stephen T. Kajdasz, Megan E. McLellan, Matthew P. Frosch, Manik Debnath, Daniel Holt, Yanming Wang, Guo-feng Huang, Chester A. Mathis, and Bradley T. Hyman
33(14)
In Vivo Magnetic Resonance of Amyloid Plaques in Alzheimer's Disease Model Mice
Einar M. Sigurdsson, YoussefZaim Wadghiri, Marcin Sadowski, James I. Elliott,Yongsheng Li, Henrieta Scholtzova, Cheuk Ying Tang, Gilbert Aguilnaldo, Karen Duff, Daniel H. Turnbull, Thomas Wisniewski
47(14)
Measuring Progression in Alzheimer's Disease Using Sserial MRI: 4D MRI
NC Fox, JM Schott, RI Scahill
61(14)
Validating MRI Measures of Disease Stage and Progression in Alzheimer's Disease
Clifford R. Jack, Jr., M.D.
75(12)
Dynamic Mapping of Alzheimer's Disease
Paul M. Thompson, Kiralee M. Hayashi, Greig de Zubicaray, Andrew L. Janke, Elizabeth R. Sowell, Stephen E. Rose, James Semple, David Herman, Michael S. Hong, Stephanie S. Dittmer, David M. Doddrell, Arthur W. Toga
87(26)
Development of Benzothiazole Amyloid-Imaging Agents
William E. Klunk, Yanming Wang and Chester A. Mathis
113(10)
First PET Study with a Benzothiazol Amyloidimaging Agent (PIB) in Alzheimer's Disease Patients and Healthy Volunteers
Henry Engler, Agneta Nord berg, William Klunk, Gunnar Blomqvist, Daniel Holt, Yanming Wang, Mats Bergstrom, Guo-feng Huang, Sergio Estrada, Manik Debnath, Julien Barletta, Johan Sandell, Anders Wall, Gunnar Antoni, Chester Mathis, Bengt Långström
123(16)
Mild Cognitive Impairment (MCI): Predicting Conversion to Clinically Probable Alzheimer's Disease with Fluoro-Deoxy-Glucose PET
J-C Baron, G. Chételat, B. Desgranges, F. Eustache
139(12)
Positron Emission Tomography and Magnetic Resonance Imaging in the Study of Cognitively Normal Persons at Differential Genetic Risk for Alzheimer's Dementia
Eric M. Reiman, Richard J. Caselli, Kewei Chen, and Gene E. Alexander
151(28)
Subject Index 179

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