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9780521854825

Cognition and Cancer

by
  • ISBN13:

    9780521854825

  • ISBN10:

    0521854822

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2008-12-15
  • Publisher: Cambridge University Press
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Summary

Most people afflicted by cancer will experience cognitive impairment, sometimes referred to as 'chemobrain' or 'chemofog', due to the various direct and indirect effects of their disease and its treatment. In addition, patients with primary or metastatic tumors of the brain experience direct neurologic symptoms due, for example, to the location of their disease, surgical intervention, and the late effects of treatment such as radiotherapy. The aim of this book is to serve as a resource for health care professionals working with cancer patients who experience cognitive changes as a result of their cancer and its treatment. It provides practical information to help improve care by reviewing and describing brain-behavior relationships; research-based evidence on cognitive changes that occur with various cancers and cancer treatments; assessment techniques, including neurocognitive assessment and neuroimaging techniques; and intervention strategies for affected patients. In short, it will explain how to identify, assess and treat these conditions.

Author Biography

Christina A. Meyers is Professor and Chief of the Section of Neuropsychology, Department of Neuro-Oncology at The University of Texas M. D. Anderson Cancer Center, Houston, Texas. James R. Perry holds the Tony Crolla Chair in Brain Tumour Research and is Head of the Division of Neurology at the Sunnybrook Health Sciences Centre and Odette Cancer Centre, University of Toronto, Canada.

Table of Contents

List of contributorsp. vii
Prefacep. xi
Cognition and the brain: measurement, tools, and interpretation
Introductionp. 3
Clinical neuropsychologyp. 6
Brain imaging investigation of chemotherapy-induced neurocognitive changesp. 19
Role of Neuropsychological assessment in cancer patientsp. 33
Neuropsychological assessment of adults with cancerp. 44
Neuropsychological assessment of children with cancerp. 56
Effects of cancer and cancer treatment on cognition
Biological bases of radiation injury to the brainp. 83
Cognitive dysfunction related to chemotherapy and biological response modifiersp. 97
Effect of hormones and hormonal treatment on cognitionp. 115
Low-grade Gliomasp. 142
High-grade Gliomasp. 156
Brain metastasesp. 170
Primary central nervous system lymphomap. 187
Childhood brain tumorsp. 198
Neurofibromatosisp. 211
Hematological malignanciesp. 228
Paraneoplastic disordersp. 239
Symptomatic therapies and supportive care issuesp. 258
Animal models and cancer-related symptomsp. 270
Interventions and implications for clinical trials
Behavioral strategies and rehabilitationp. 281
Support servicesp. 295
Pharmacological Interventions for the treatment of radiation-induced brain injuryp. 312
Neurocognitive testing in clinical trialsp. 320
Indexp. 329
Table of Contents provided by Ingram. All Rights Reserved.

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