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9783527304417

Cancer Immune Therapy : Current and Future Strategies

by ; ; ;
  • ISBN13:

    9783527304417

  • ISBN10:

    352730441X

  • Format: Hardcover
  • Copyright: 2002-12-01
  • Publisher: Wiley-VCH

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Summary

Cure or life with cancer? What can be achieved by cancer immune therapy? The past decade has seen substantial advancements in tumor immunology. Much of the new knowledge has been translated into new strategies for cancer treatment and into clinical trials. Some of these trials herald future breakthroughs, others have been disappointing and have prompted intensive search for alternatives.Major contributors to the field summarize the knowledge on the molecular and cellular mechanisms of tumorigenesis, critically review the instruments of the immune system that might be exploited for therapy, and discuss the clinical experiences with the different immune therapy concepts. Researchers in the fields of immunology, tumor biology and medicine will highly appreciate this up-to-date volume for evaluating future research activities.

Table of Contents

TUMOR ANTIGENICITY.
Search for Universal Tumor Associated T Cell Epitopes.
Serological Determinants.
Processing and Presentation of Tumor-Associated Antigens.
T Cells in Anti-Tumor Immunity.
IMMUNE EVASION AND SUPPRESSION.
MHC Modulation and Loss.
Immune Cells in the Tumor Microenvironment.
Immunosuppressive Factors in Cancer Immunity.
Interleukin 10 and Cancer.
STRATEGIES FOR CANCER IMMUNE THERAPY.
Dendritic Cells in Tumor Immunology and Cancer Immune Therapy.
Gene Technological Approaches to Immune Therapy of Cancer.
Hybrid Cell Vaccination.
Principles and Strategies employing Heat Shock Proteins.
Application of CpG Motifs from Bacterial DNA.
The T-Body Approach.
Bone Marrow Transplants.
Immunocytokines: Versatile Molecules for Biotherapy.
Immunotoxins and Recombinant Immunotoxins in Cancer Therapy.

Supplemental Materials

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The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.

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