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9781588291677

Cancer Diagnostics

by ; ; ;
  • ISBN13:

    9781588291677

  • ISBN10:

    1588291677

  • Format: Hardcover
  • Copyright: 2004-08-01
  • Publisher: Humana Pr Inc

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Summary

High-profile laboratory scientists and basic cancer researchers review those recent and future clinical laboratory tests that can help in the early detection, evaluation, and prediction of human tumors, and so permit more informed therapeutic decisions. Emphasizing the importance of molecular and genetic RNA/DNA tests that can detect persons at high risk for specific cancers, the authors explore these novel serological assays, cellular assays useful for anatomic pathology, and molecular and genetic assays. Highlights include a profile of genetic tests for the diagnosis of colon, lung, and pancreatic cancers and a discussion of the molecular microsatellite instability that is observed in many cancers and permits the diagnosis of particular cancers. Informative and state-of-the-art, Cancer Diagnostics: Current and Future Trends illuminates coming future developments and tests for cancer diagnosis and monitoring, and make clear that early diagnosis and detection of cancer will become a reality in the future.

Table of Contents

Preface v
Contributors ix
Part I: Introduction
General Considerations in the Use and Application of Laboratory Tests for the Evaluation of Cancer
3(12)
Robert M. Nakamura
Wayne W. Grody
New Insights and Future Advances in Cancer Diagnostics: Limitations of Conventional Tumor Markers
15(12)
Yasushi Kasahara
Yutaka Tsukada
The Changing Role of the Pathologist in the Management of the Cancer Patient
27(8)
Raymond B. Nagle
Part II: Serological Tumor Markers
Types of Circulating Tumor Markers and Their Clinical Applications
35(18)
James T. Wu
Identification of Risk Factors for Early Neoplasm
53(12)
James T. Wu
Emerging Circulating Tumor Markers
65(20)
James T. Wu
Prostate Cancer Markers: From Discovery to the Clinic
85(44)
Judith A. Finlay
Stephen D. Mikolajczyk
Thomas M. Pribyl
R. Bruce Wallace
Harry G. Rittenhouse
Serum Tumor Marker Test Profile in Testicular Germ-Cell Tumors
129(40)
Frank J. Liu
Robert M. Nakamura
C. Howard Tseng
Kevin S. Liu
Autoantibodies, Autoimmunity, and Cancers: Markers for Identification of Early Stages of Tumors
169(16)
Robert M. Nakamura
Eng M. Tan
Part III: Cellular Tumor Markers
MHC Tetramers: A Tool for Direct Ex Vivo Detection and Enumeration of Tumor-Specific Cytotoxic T Lymphocytes
185(14)
Jennie C. C. Chang
Ferdynand Kos
Charles T. Nugent
Kristine Kuus-Reichel
New Applications of Flow Cytometry in Cancer Diagnosis and Therapy
199(34)
Sophie Song
Faramarz Naeim
Molecular Diagnostics in Neoplastic Hematopathology
233(28)
Daniel A. Arber
HER2 and Topoisomerase IIα in Breast Carcinoma
261(24)
Kenneth J. Bloom
Study of Sentinel Lymph Nodes in the Staging of Malignant Neoplasms
285(22)
Alice A. Roberts
Alistair J. Cochran
A Marker for Early Diagnosis of Lung Cancer: The Heterogeneous Nuclear Ribonucleoprotein A2/B1 (hnRNP A2/B1)
307(18)
Jordi Tauler
Alfredo Martinez
James L. Mulshine
Part IV: Molecular and Genetic Tumor Markers
Molecular Techniques in Cancer Diagnosis and Management
325(36)
Jeffrey S. Ross
Karen Gray
Rebecca Mosher
James Stec
DNA Repair Defects in Cancer
361(18)
Ramune Reliene
Robert H. Schiestl
Chromosomal and Molecular Cytogenetic Assays for Evaluation of Human Tumors
379(16)
Peter C. Hu
Vicki L. Hopwood
Armand B. Glassman
Microsatellite Alterations as Diagnostic and Prognostic Molecular Markers in Patients With Cancer
395(34)
Bret Taback
Dave S. B. Hoon
Recent Advances in Molecular Classification and Prognosis of Colorectal Cancer
429(24)
Tsung-Teh Wu
Asif Rashid
Genetic Counseling for Hereditary Cancer Predisposition Testing
453(20)
Joyce L. Seldon
Patricia A. Ganz
Diagnosis of Ataxia-Telangiectasia: ATM Mutations Associated With Cancer
473(16)
Midori Mitsui
Shareef A. Nahas
Helen H. Chun
Richard A. Gatti
Index 489

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The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.

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