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9780721685779

Applied Pharmacology for the Veterinary Technician

by ;
  • ISBN13:

    9780721685779

  • ISBN10:

    0721685773

  • Format: Paperback
  • Copyright: 2000-04-01
  • Publisher: Elsevier Science Health Science div
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List Price: $36.95

Summary

Here's the revised and updated edition of the innovative reference, presenting the fundamental principles of pharmacology, administration of drugs, and pharmacologic calculations. Addresses all major categories of drugs in a consistent format including pharmacokinetics, pharmacodynamics, adverse side effects, clinical uses, and dosage forms. Illustrated, step-by-step procedures demonstrate the administration of common drug forms.

Table of Contents

General Pharmacology
1(22)
Introduction
2(1)
Drug Sources
3(1)
Pharmacotherapeutics
3(1)
Pharmacokinetics
4(9)
Routes of Administration
6(2)
Drug Absorption
8(1)
Drug Distribution
9(1)
Biotransformation
10(1)
Drug Excretion
11(2)
Pharmacodynamics
13(2)
Drug Names
15(1)
Drug Labels
15(2)
Development and Approval of New Drugs
17(2)
Regulatory Agencies
17(1)
The Food Animal Residue Avoidance Databank
17(2)
Steps in the Development of a New Drug
19(1)
Federal Laws Relating to Drug Development and Use
19(2)
The Animal Medicinal Drug Use Clarification Act
19(1)
Compounding of Veterinary Drugs
20(1)
The Veterinary Feed Directive
20(1)
Dispensing Versus Prescribing Drugs
21(1)
Marketing of Drugs
21(2)
Routes and Techniques of Drug Administration
23(26)
Dosage Forms
24(7)
Drug Preservatives and Solvents
31(1)
Drug Administration
31(14)
Oral Medications
31(4)
Parenteral Medications
35(8)
Inhalation Medications
43(2)
Topical Medications
45(1)
Medication Orders
45(1)
Controlled Substances
46(1)
Client Education
47(2)
Practical Calculations in Pharmacology
49(16)
Introduction
50(1)
Mathematics Fundamentals
50(1)
Systems of Measurement
51(3)
The Metric System
51(1)
Conversion Between Metric Units
52(2)
The Apothecary and Household Systems
54(1)
Dosage Calculations
54(1)
Solutions
55(1)
Percent Concentrations
56(1)
Calculations Involving Concentrations
56(1)
Milliequivalents
57(1)
Calculations Involving IV Fluid Administration
57(8)
Calculations for Constant Rate Infusion Problems
58(7)
Drugs Used in Nervous System Disorders
65(28)
Introduction
66(1)
Anatomy and Physiology
67(4)
Autonomic Nervous System
71(4)
How Drugs Affect the Autonomic Nervous System
74(1)
Classes of Autonomic Nervous System Drugs
75(3)
Cholinergic Agents
75(1)
Cholinergic Blocking Agents (Anticholinergic)
75(1)
Adrenergic (Sympathomimetic) Agents
76(1)
Adrenergic Blocking Agents
77(1)
Central Nervous System
78(10)
Tranquilizers
78(2)
Barbiturates
80(2)
Dissociative Agents
82(1)
Opioid Agonists
83(2)
Opioid Antagonists
85(1)
Neuroleptanalgesics
85(1)
Drugs to Prevent or Control Seizures
85(1)
Miscellaneous Central Nervous System Drugs
86(1)
Central Nervous System Stimulants
87(1)
Caffeine
88(1)
Amphetamines
88(1)
Behavioral Pharmacotherapy
88(2)
Anti-Anxiety Medications
88(1)
Antidepressants
89(1)
Euthanasia Agents
90(3)
Drugs Used In Respiratory System Disorders
93(12)
Introduction
94(1)
Respiratory Anatomy and Physiology
94(2)
Respiratory Defense Mechanisms
96(1)
Principles of Respiratory Therapeutics
97(1)
Categories of Respiratory Drugs
97(8)
Expectorants
97(1)
Mucolytics: Acetylcysteine
97(1)
Antitussives: Centrally Acting Agents
98(2)
Bronchodilators
100(2)
Decongestants
102(1)
Antihistamines
102(1)
Miscellaneous Respiratory Drugs
102(3)
Drugs Used in Renal and Urinary Tract Disorders
105(14)
Introduction
106(2)
Physiologic Principles
108(3)
Renal Failure
111(1)
Common Drugs for the Treatment of Renal Dysfunction and Associated Hypertension
111(4)
Diuretic Drugs
111(1)
Cholinergic Agonists
112(1)
Anticholinergic Drugs
113(1)
Adrenergic Antagonists
113(1)
Angiotensin-Converting Enzyme Inhibitors
114(1)
Vasodilators and Calcium Channel Blockers
114(1)
Antidiuretic Hormone
114(1)
Urinary Acidifiers
115(1)
Xanthine Oxidase Inhibitors
115(1)
Urinary Alkalizers
115(1)
Pharmacotherapy of Renal Failure Complications
115(1)
Pharmacotherapy of Urinary Incontinence
116(1)
Technician's Role
117(2)
Drugs Used in Cardiovascular System Disorders
119(18)
Introduction
120(1)
Anatomy and Physiology of the Heart
120(3)
Compensatory Mechanisms of the Cardiovascular System
123(2)
Basic Objectives in the Treatment of Cardiovascular Disease
125(1)
Categories of Cardiovascular Drugs
125(8)
Positive Inotropic Drugs
125(3)
Antiarrhythmic Drugs
128(2)
Vasodilator Drugs
130(3)
Diuretics
133(1)
Dietary Management of Heart Disease
133(1)
Ancillary Treatment of Heart Failure
134(3)
Bronchodilators
134(1)
Oxygen Therapy
134(1)
Sedation
134(1)
Aspirin
134(1)
Thoracentesis and Abdominocentesis
134(3)
Drugs Used in Gastrointestinal System Disorders
137(20)
Introduction
138(1)
Anatomy and Physiology
138(3)
Regulation of the Gastrointestinal System
141(1)
Vomiting
142(4)
Emetics
143(1)
Antiemetics
144(2)
Antiulcer Medications
146(2)
H2 Receptor Antagonists
146(1)
Proton Pump Inhibitors
147(1)
Antacids
148(1)
Gastromucosal Protectants
148(1)
Prostaglandin E-1 Analogs
148(1)
Diarrhea
148(2)
Antidiarrheal Medications
149(1)
Laxatives
150(2)
Saline/Hyperosmotic Agents
150(1)
Bulk-Producing Agents
151(1)
Lubricants
151(1)
Surfactant/Stool Softeners
151(1)
Irritants
152(1)
Gastrointestinal Prokinetics/Stimulants
152(1)
Dopaminergic Antagonists
152(1)
Serotonergic Drugs
152(1)
Motilin-Like Drugs
152(1)
Direct Cholinergics
153(1)
Acetylcholinesterase Inhibitors
153(1)
Digestive Enzymes
153(1)
Miscellaneous Gastrointestinal Drugs
153(1)
Antibiotics
153(1)
Anti-Inflammatory Agents
154(1)
Antifoaming Agents
154(1)
Oral Products
154(3)
Dentifrice and Oral Cleansing Products
155(1)
Fluoride Products
155(1)
Perioceutic Agents
155(1)
Polishing Paste
155(1)
Disclosing Solution
155(2)
Drugs Used in Hormonal, Endocrine, And Reproductive Disorders
157(22)
Introduction
158(1)
Anatomy and Physiology
159(3)
Pituitary Gland
159(1)
Control of the Endocrine System
160(2)
Hormonal Drugs Associated with Reproduction
162(6)
Gonadotropins and Gonadal Hormones
162(3)
Prostaglandins
165(2)
Drugs Affecting Uterine Contractility
167(1)
Pheromones
168(1)
Thyroid Hormones
168(7)
Drugs Used to Treat Hypothyroidism
169(1)
Drugs Used to Treat Hyperthyroidism
170(1)
Agents for the Treatment of Diabetes Mellitus
170(5)
Hyperglycemic Agents
175(1)
Hormones That Act as Growth Promoters
175(1)
Sex Steroids, Synthetic Steroid Analogs, and Non-Steroidal Analogs
175(1)
Growth Hormone:Bovine Somatotropin, Bovine Growth Hormone
176(1)
Anabolic Steroids
176(3)
Stanozolol
177(1)
Boldenone Undecylenate
177(1)
Nandrolone Decanoate
177(2)
Drugs Used in Ophthalmic and Otic Disorders
179(12)
Ophthalmic Agents
180(6)
Mydriatics and Cycloplegics
180(2)
Miotics
182(1)
Other Agents That Reduce Intraocular Pressure
182(1)
Topical Anesthetics
183(1)
Ophthalmic Stains
184(1)
Collagen Shields
184(1)
Topical Ophthalmic Anti-Infectives
184(1)
Antifungal Agents
184(1)
Antibacterial Agents
185(1)
Topical Ophthalmic Anti-Inflammatory Agents
185(1)
Agents for the Treatment of Keratoconjunctivitis Sicca
186(1)
Otic Drugs
186(5)
Introduction
186(1)
Topical Otic Anti-Infective Agents
186(2)
Antiparasitics
188(1)
Drying Agents
189(1)
Cleaning Agents
189(2)
Drugs Used in Skin Disorders
191(14)
Introduction
192(1)
Anatomy and Physiology
192(1)
Topical Antiseborrheics
193(3)
Sulfur
193(2)
Salicylic Acid
195(1)
Coal Tar
195(1)
Benzoyl Peroxide
195(1)
Selenium Sulfide
195(1)
Topical Medications Mixed with Water
196(1)
Aluminum Acetate
196(1)
Magnesium Sulfate
196(1)
Bath Oils
196(1)
Topical Antipruritics
197(1)
Non-Steroidal Antipruritics
197(1)
Topical Corticosteroids
197(1)
Astringents
197(1)
Antiseptics for the Skin
197(2)
Alcohols
198(1)
Propylene Glycol
198(1)
Chlorhexidine
198(1)
Acetic Acid
198(1)
Iodine
198(1)
Benzalkonium Chloride
198(1)
Wound Healing
199(1)
Topical Wound Dressings
199(1)
Healing Stimulators
199(1)
Wound Cleansers
199(1)
Protectants
200(1)
Other Drugs Used in Dermatologic Therapy
200(2)
Systemic Corticosteroids
200(1)
Topical Antibacterial Agents
201(1)
Topical Antifungal Agents
201(1)
Fatty Acid Supplements
201(1)
Counterirritants
202(1)
Caustics
203(2)
Anti-Infective Drugs
205(22)
Introduction
206(1)
Mechanism of Action
207(1)
Penicillins
208(3)
Pharmacokinetics
208(1)
Pharmacodynamics
208(3)
Cephalosporins
211(1)
Pharmacokinetics
211(1)
Pharmacodynamics
211(1)
Tetracyclines
211(3)
Pharmacokinetics
213(1)
Pharmacodynamics
213(1)
Aminoglycosides
214(1)
Pharmacokinetics
214(1)
Pharmacodynamics
215(1)
Fluoroquinolones
215(1)
Pharmacokinetics
215(1)
Pharmacodynamics
215(1)
Other Anti-Infectives
216(3)
Chloramphenicol
216(1)
Florfenicol
216(1)
Macrolides and Lincosamides
217(1)
Vancomycin
217(1)
Spectinomycin
218(1)
Polymyxin B and Bacitracin
218(1)
Sulfonamides
218(1)
Nitrofurans
219(1)
Antifungal Drugs
219(2)
Polyene Antifungal Agents
219(1)
Imidazole Antifungal Agents
220(1)
Antimetabolic Antifungal Agents
220(1)
Superficial Antifungal Agents
220(1)
Other Antifungal Agents
221(1)
Antiviral Drugs
221(1)
Acyclovir
221(1)
Interferon Alfa-2A, Human Recombinant
221(1)
Disinfectants/Antiseptics
221(6)
Alcohols
222(1)
Ethylene Oxide
223(1)
Formaldehyde
223(1)
Chlorines and Iodines
223(1)
Phenolics: Saponated Cresol, Semi-Synthetic Phenols
224(1)
Quaternary Ammonium Compounds: Cationic Detergents
224(1)
Biguanide Compounds
224(1)
Other Disinfectants
225(2)
Antiparasitic Drugs
227(22)
Introduction
228(1)
Endoparasites
228(12)
Antinematodal
229(9)
Anticestodal
238(1)
Antitrematodal
238(1)
Antiprotozoal
239(1)
Heartworm Disease
240(2)
Adulticides
240(1)
Microfilaricides
241(1)
Preventatives
241(1)
Ectoparasites
242(7)
Application Systems
242(3)
Insecticides
245(4)
Drugs Used to Relieve Pain and Inflammation
249(18)
Introduction
250(1)
Anatomy and Physiology
251(1)
Non-Steroidal Anti-Inflammatory Agents
251(5)
Salicylates
252(2)
Pyrazolone Derivatives
254(1)
Flunixin Meglumine (Banamine)
254(1)
Dimethyl Sulfoxide
255(1)
Acetaminophen
255(1)
Propionic Acid Derivatives
255(1)
Other Non-Steroidal Anti-Inflammatory Drugs
256(1)
Etodolac
256(1)
Opioid Analgesics
257(1)
Opioid Agonists
257(1)
Opioid Agonists-Antagonists
257(1)
Opioid Partial Agonists
258(1)
Antihistamines
258(1)
H1 Blockers
259(1)
H2 Blockers
259(1)
Muscle Relaxants
259(1)
Methocarbamol (Robaxin-V)
259(1)
Other Muscle Relaxants
259(1)
Corticosteroids
259(4)
Injectables
262(1)
Oral
262(1)
Topical
262(1)
Local, Regional, and Topical Anesthetic Agents
263(4)
Injectable
265(1)
Topical
265(2)
Therapeutic Nutritional, Fluid, and Electrolyte Replacements
267(26)
Introduction
268(1)
Anatomy, Physiology, and Chemistry
268(4)
Distribution of Body Water and Electrolytes
268(1)
Composition of Body and Therapeutic Fluids
269(1)
Osmotic Pressure and Tonicity of Fluids
270(2)
Principles of Fluid Therapy
272(10)
Indications for Fluid Therapy
273(1)
Fluid Balance
273(1)
History, Physical Examination, and Laboratory Findings
273(2)
Determining the Amount of Fluid to Administer
275(1)
Routes of Fluid Administration
275(2)
Rate of Administration
277(1)
Monitoring Fluid Administration
278(2)
Preparing Fluid Administration Equipment
280(2)
Types of Solution Used in Fluid Therapy
282(5)
Crystalloid Solutions
282(1)
Colloid Solutions
283(1)
Hypertonic Solutions
284(1)
Fluid Additives
284(3)
Oral Electrolyte Preparations
287(1)
Parenteral Vitamin/Mineral Products
288(5)
Water-Soluble Vitamins
288(1)
Fat-Soluble Vitamins
289(4)
Blood-Modifying, Antineoplastic, and Immunosuppressant Drugs
293(20)
Introduction
294(1)
Blood-Modifying Drugs/Agents
294(8)
Hematinics
294(3)
Anticoagulants
297(3)
Hemostatics/Anticoagulant Antagonists
300(1)
Fibrinolytic (Thrombolytic) Drugs
301(1)
Antineoplastic Drugs
302(7)
Alkylating Agents
303(2)
Antimetabolites
305(1)
Plant Alkaloids
306(1)
Antibiotic Antineoplastic Agents
306(1)
Hormonal Antineoplastic Agents
306(1)
Miscellaneous Antineoplastic Agents
306(1)
Biologic Response Modifiers
307(2)
Immunosuppressive Drugs
309(4)
Azathioprine
309(1)
Cyclosporine
309(1)
Metronidazole
310(1)
Cyclophosphamide
310(1)
Corticosteroids
310(3)
Immunologic Drugs
313(16)
Principles of Vaccination
314(1)
Common Vaccine Types That Produce Active Immunity
315(2)
Inactivated
315(1)
Live
315(1)
Modified Live
315(1)
Recombinant
316(1)
Toxoid
316(1)
Common Vaccine Types That Produce Passive Immunity
317(1)
Antitoxin
317(1)
Antiserum
317(1)
Other Types of Vaccines
317(1)
Autogenous Vaccine
317(1)
Mixed Vaccine
317(1)
Administration of Vaccines
318(1)
Biologic Care and Vaccine Failure
319(1)
Adverse Vaccination Responses
319(1)
Vaccines for Preventive Health Programs
320(6)
Canine
320(1)
Equine
320(1)
Feline
320(1)
Bovine
320(5)
Others
325(1)
Immunotherapeutic Drugs
326(3)
Immunostimulants
326(3)
Miscellaneous Therapeutic Agents
329(10)
Alternative Medicines
330(3)
Chondroprotectives
330(1)
Nutraceuticals
330(3)
Miscellaneous Antidotes
333(3)
Activated Charcoal
333(1)
Calcium EDTA
333(1)
Methylene Blue
333(1)
Acetylcysteine
334(1)
Dimercaprol
334(1)
Pralidoxime Chloride
334(1)
Penicillamine
335(1)
Sodium Thiosulfate
335(1)
Ethanol
335(1)
Fomepizole
336(1)
Reversal Agents
336(1)
Atipamezole HCl
336(1)
Flumazenil
336(1)
Naloxone HCl
336(1)
Tolazoline HCl
336(1)
Yohimbine HCl
337(1)
Lubricants
337(2)
Appendix A Common Abbreviations Used in Veterinary Medicine 339(2)
Appendix B Weights and Measures 341(2)
Appendix C Emergency Drugs 343(2)
Appendix D Controlled Substances Information Summary 345(2)
Appendix E Conversion of Body Weight in Kilograms to Body Surface Area in Meters for Dogs 347(2)
Bibliography 349(4)
Answers 353(22)
Index 375

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