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9783764365950

Antirheumatic Therapy

by ; ; ;
  • ISBN13:

    9783764365950

  • ISBN10:

    3764365951

  • Format: Hardcover
  • Copyright: 2005-02-14
  • Publisher: Birkhauser

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Summary

This book gives a comprehensive overview of disease-modifying antirheumatic drugs (DMARDs). The introductory general chapters deal with the chemistry of DMARDs, their use in therapy, pharmacoeconomics, and a survey of opinion leaders in the field; the following specific chapters characterize each agent with regard to mechanism of action, therapy, pharmacology, efficacy, toxicity, and monitoring. For each agent some background is given, recent developments and influence of the treatment on patients' quality of life and long-term outcomes are presented.

Table of Contents

List of contributors vii
Preface xi
Garry G. Graham
Medicinal chemistry of the disease modifying anti-rheumatic drugs
1(24)
Maria E. Suarez-Almazor
Targeting DMARD therapy
25(24)
Andreas Maetzel and Daniel H. Solomon
Pharmacoeconomic properties of disease-modifying anti-rheumatic drugs
49(20)
Edward C. Keystone and Boulos Haraoui
Future molecular targets
69(12)
Beau Bothwell and Daniel E. Furst
Hydroxychloroquine
81(12)
Cees J. Haagsma
Sulfasalazine
93(40)
Rolf Rau
Parenteral gold
133(30)
David Kane and Barry Bresnihan
Azathioprine
163(12)
Kevin Pile
Methotrexate
175(24)
Alberta Hoi and Geoffrey Littlejohn
Leflunomide
199(22)
Arno W.R. van Kuijk and Ben A.C. Dijkmans
Cyclosporin
221(16)
Kristin Bird and James R. O'Dell
Tetracyclines
237(10)
John R. Kirwan and Mark G. Perry
Systemic glucocorticoids in rheumatoid arthritis
247(18)
Zuhre Tutuncu and Arthur Kavanaugh
TNF-a inhibitors
265(14)
Barry Bresnihan
Anakinra in rheumatoid arthritis
279(14)
Ernest Choy and Harold E. Paulus
Combination therapy
293(26)
Alan Tyndall and Jacob M. van Laar
Hematopoietic stem cell transplantation for the treatment of severe autoimmune diseases
319(18)
Index 337

Supplemental Materials

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