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9781617283499

Feasibility of Vehicle-based Sensors to Detect Drowsy Driving and Alcohol Impairment (With Accompanying Cd-rom)

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  • ISBN13:

    9781617283499

  • ISBN10:

    1617283495

  • Format: Hardcover
  • Copyright: 2014-11-15
  • Publisher: Nova Science Pub Inc
  • Purchase Benefits
List Price: $120.00

Summary

Mitochondria are central to ATP synthesis, regulation of Ca2+ homeostasis generation of reactive oxygen species and programmed cell death. They have an essential role in generation of cell activation signals via released reactive species, as well as small GTPases, mitogen activated kinases located in the outer and inner membranes of mitochondria. While mutations of mitochondrial DNA leading to synthesis of malfunctional proteins are the most understood cause of cellular/organelle pathological changes, the mitochondrial dysfunction induced via oxidative damage to DNA, electron transport chain and structural proteins are also etiologically important events in development and progression in a wide array of diseases. This book reviews the newest discoveries supporting implication of mitochondria in inflammatory and apoptosis-based diseases.

Table of Contents

Introduction
Ros & The Mitochondrial Electron Transport Chain
Rho Family Gtpases & Mitochondria
Rho Proteins & Apoptosis
Rho Proteins & Ros
Iron-Mediated Mitochondrial Dysfunctions
Molecular Aspects of Etc Dysfunction By Lipoperoxidation
Thiol Oxidation in the Mechanism of ETC Inhibition by Ros
Mitochondrial Dysfunction & Hypertension
Mitochondrial Dysfunction & Allergic Inflammation
Mitochondrial Dysfunctions & K-Atp Channels
Conclusion
Index
Table of Contents provided by Publisher. All Rights Reserved.

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