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9780387351360

Neural Crest Induction And Differentiation

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  • ISBN13:

    9780387351360

  • ISBN10:

    0387351361

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2006-09-01
  • Publisher: Landes Bioscience
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Summary

Neural Crest Induction and Differentiation, written by an international panel of recognized leaders in the field, discusses all aspects of modern neural crest biology from its evolutionary significance, to its specification, migration, plasticity and contribution to multiple lineages of the vertebrate body, to the pathologies associated with abnormal neural crest development and function. Each chapter provides an invaluable resource for information on the most current advances in the field, with discussion of controversial issues and areas of emerging importance.

Table of Contents

Neural Crest Cells and The Community of Plan for Craniofacial Development: Historical Debates and Current Perspectives
1(23)
Drew M. Noden
Richard A. Schneider
Introduction
1(1)
Primary Germ Layers and Neural Crest Cell Lineages
2(2)
Neural Crest and the Cranial Bauplan
4(6)
Topology and Homology along the Neural Crest-Mesoderm Interface
10(4)
Neural Crest and the Origins of Craniofacial Pattern
14(3)
Conclusion
17(7)
Neural Crest Inducing Signals
24(8)
Martin L. Basch
Marianne Bronner-Fraser
Introduction
24(1)
Signals from the Ectoderm
25(1)
Signals from the Mesoderm
25(1)
BMPs
25(2)
Wnts
27(1)
FGFs
28(1)
Notch
28(1)
Neural Crest Induction Is a Multistep Process
29(1)
Conclusions
29(3)
Transcriptional Regulation at the Neural Plate Border
32(13)
Thomas D. Sargent
Introduction
32(1)
DIx and Msx Genes
33(5)
TFAP2
38(3)
NC Regulatory Pathways Problems and Prospects
41(4)
Neural Crest Delamination and Migration: Integrating Regulations of Cell Interactions, Locomotion, Survival and Fate
45(33)
Jean-Loup Duband
Introduction
45(1)
Neural Crest Delamination: Their Declaration of Independence
46(18)
Neural Crest Migration: How to Survive, Move and Develop in a Hostile Environment
64(7)
Conclusion
71(7)
Neural Crest Cell Plasticity: Size Matters
78(18)
Lisa L. Sandell
Paul A. Trainor
Introduction
78(2)
Hindbrain, Hox Genes and Axial Identity
80(1)
Environment Influences Neural Crest/Neural Crest Influences Environment
81(1)
Neural Crest Plasticity Is Influenced by Graft Size and Developmental Age
82(3)
Plasticity in Neural Crest Cell Migration
85(1)
Neural Crest Cells Direct Species-Specific Craniofacial Morphology
86(2)
Patterning of the Head and Face by Non-Neural Crest Tissues
88(1)
Molecular Pathways Involved in Neural Crest Signaling
88(1)
Reciprocal Interactions
89(1)
Conclusions
90(6)
The Contribution of the Neural Crest to the Vertebrate Body
96(24)
Elisabeth Dupin
Sophie Creuzet
Nicole M. Le Douarin
Introduction
96(1)
The Derivatives of the NC
97(1)
Pathways and Molecular Control of NCC Migration
98(3)
The Mesectoderm Is at the Origin of Most Head Structures
101(2)
The Posterior Limit of the NC-Derived Skeleton in Mammals
103(1)
Contribution of the Mesectoderm to the Cardiovascular and Periocular Structures
103(2)
Hox Gene Expression in the Cephalic NCCs and Their Derivatives
105(2)
Shifting Rostrally the Limit of Hox Gene Expression
107(1)
Patterning the Facial Skeleton by the Pharyngeal Endoderm
107(2)
Role of the Superficial Facial Ectoderm in Shaping the Face
109(1)
Heterogeneity of Progenitors and Stem Cells in the Early NC
110(1)
Resident NC Stem Cells Are Present in Differentiated Tissues up to Adulthood
111(1)
Plasticity of NC-Derived Phenotypes
111(2)
Concluding Remarks
113(7)
Cranial Neural Crest and Development of the Head Skeleton
120(14)
Robert D. Knight
Thomas F. Schilling
Introduction
120(1)
Specification and Migration of the Skeletogenic CNC
120(4)
Patterning Influences of Skeletogenic CNC on Surrounding Tissues
124(1)
Patterning within Pharyngeal Arch Primordia
124(2)
Endoderm Patterns CNC and Is Required for Skeletal Development
126(2)
Pharyngeal Ectoderm Patterns CNC
128(1)
CNC Development and Evolution
129(1)
Summary and Conclusions
130(4)
Neural Crest Contribution to the Cardiovascular System
134(21)
Christopher B. Brown
H. Scott Baldwin
Introduction
134(2)
Identification and Characterization of the Cardiac Neural Crest
136(1)
Cardiac Neural Crest Function in Cardiac Development and Remodeling
136(2)
Neural Crest Ablation
138(1)
Cardiac Neural Crest Function in Pharyngeal Arch Patterning
139(1)
Cardiac Neural Crest in Outflow Tract Septation and Alignment
139(2)
Myocardial Dysfunction, Elongation, Alignment and the Secondary Heart Field
141(2)
Molecular Pathways
143(1)
Mouse Model of Cardiac Neural Crest Deficiency
144(1)
Neurotrophins
144(1)
Forkhead Transcription Factors FoxC1/FoxC2
144(1)
Tbx1, Fibroblast Growth Factors and DiGeorge Syndrome
145(1)
Retinoic Acid
146(1)
Cell-Cell Contact (Connexins)
146(1)
Platelet Derived Growth Factor (PDGF)
146(1)
Endothelin
147(1)
TGFβ Superfamily Members
147(1)
Semaphorins
148(1)
Pitx2 and Laterality
148(1)
Summary
149(6)
The Genetic Regulation of Pigment Cell Development
155(15)
Debra L. Silver
Ling Hou
William J. Pavan
Introduction
155(1)
Model Organisms
156(1)
Initial Induction and Expansion of the Pigment Cell Population
157(2)
Pigment Cell Specification, Differentiation and Survival
159(2)
Pigment Cell Migration and Development: Cell Adhesion and Signaling
161(3)
Concluding Thoughts
164(6)
Specification of Sensory Neuron Cell Fate from the Neural Crest
170(11)
David W. Raible
Josette M. Ungos
The Form and Function of Dorsal Root Ganglia Neurons
170(1)
Neural Crest Origin of the Sensory Ganglia
171(1)
Sensory Neuron Cell Types
171(1)
Specification of Sensory Neurons
172(4)
Future Challenges
176(5)
Neural Crest and the Development of the Enteric Nervous System
181(16)
Richard B. Anderson
Donald F. Newgreen
Heather M. Young
The Enteric Nervous System
181(1)
Origins of the ENS
181(5)
Hirschsprung's Disease
186(1)
Proliferation, Cell Death and Differentiation in the Developing ENS
187(1)
Molecules and Signaling Pathways Involved in ENS Development
188(3)
Conclusions
191(6)
Growth Factors Regulating Neural Crest Cell Fate Decisions
197(9)
Lukas Sommer
Plasticity of the Neural Crest
197(1)
Growth Factors Regulating Neural Crest Cell Fates in Culture
198(2)
Factors Involved in Neural Crest Development in Vivo
200(3)
Conclusions
203(3)
Neural Crest Stem Cells
206(7)
Lu Teng
Patricia A. Labosky
Neural Crest Stem Cells
206(1)
Identification of Neural Crest Stem Cells (NCSCs)
206(2)
Molecular Control of NCSC Differentiation
208(2)
Postnatal NCSCs, Disease and Cell Therapy
210(3)
Molecular Bases of Human Neurocristopathies
213(22)
Heather C. Etchevers
Jeanne Amiel
Stanislas Lyonnet
Introduction
213(1)
Definition of a Neurocristopathy
214(5)
Clinical Appreciation of Neurocristopathies
219(8)
Discussion
227(8)
Evolution of the Neural Crest
235(10)
Alejandro Barrallo-Gimeno
M. Angela Nieto
Introduction: Was There Anything Like This Before?
235(1)
Neural Crest and the Neural Tube: The Only Way Is Dorsal
236(1)
Cell Migration: A Whole Body to Populate
237(1)
Consolidation of the Neural Crest Population: The More, the Merrier
238(1)
To Hox or not to Hox
238(1)
Evolution's Toolbox I. Playing with Genes and Genomes: Two Is Better Than One
239(1)
Evolution's Toolbox II. Cooption: Take Genes from Your Neighbor Cells
240(1)
Conclusions: So, What Now?
240(5)
Index 245

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