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9781556423123

Ocular Therapeutics Pharmacology and Clinical Application

by ;
  • ISBN13:

    9781556423123

  • ISBN10:

    1556423128

  • Format: Paperback
  • Copyright: 1997-11-11
  • Publisher: Slack Incorporated
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Summary

Translation of a German title in its third edition. Clinical reference for the ophthalmologist covering the treatment, etiology, pathogenesis, and clinical features of eye diseases. Softcover. DNLM: Eye Diseases--drug therapy.

Table of Contents

Dedication iii(8)
Acknowledgments xi(1)
About the Authors xii(1)
Preface xiii(1)
Foreword xiv
George O. Waring III, MD, FACS, FRCOphth
1 Pharmacokinetics of Ophthalmic Medications
1(14)
1.1 Bioavailability
1(1)
1.2 General Aspects of Pharmacokinetics
2(7)
1.3 Routes of Administration
9(3)
References
12(3)
2 Chemotherapy of Bacterial Infections
15(30)
2.1 Antibacterial Chemotherapy: General Aspects
15(8)
2.2 Antibacterial Chemotherapy: Specific Agents
23(19)
2.3 New Developments
42(1)
References
42(3)
3 Ocular Mycology and Antifungal Medications
45(14)
3.1 Ocular Mycology
45(3)
3.2 Antifungal Medications
48(8)
References
56(3)
4 Medical Therapy of Viral Infections
59(24)
4.1 Virology
59(9)
4.2 Antiviral Chemotherapeutics (Antimetabolites)
68(10)
References
78(5)
5 Cytotoxic and Immunomodulatory Drugs
83(14)
5.1 Cytotoxic Agents
83(4)
5.2 Immunosuppressive Medications
87(6)
5.3 Immune-Stimulating Therapy
93(1)
References
94(3)
6 Corticosteroids
97(10)
6.1 Chemical Structure
97(1)
6.2 Mode of Action
97(1)
6.3 Effects
98(1)
6.4 Side Effects
98(2)
6.5 Ophthalmological Indications
100(1)
6.6 Ocular Pharmacokinetics
100(3)
6.7 Preparations and Dosages
103(2)
References
105(2)
7 Nonsteroidal Anti-Inflammatory Drugs, Antihistamines, and Mast Cell Stabilizers
107(14)
7.1 Prostaglandin Synthase Inhibitors
107(6)
7.2 Leukotrience Antagonists
113(1)
7.3 Phospholipase A(2)-Inhibitors
113(1)
7.4 Inhibitors of Platelet-Activating Factors
113(1)
7.5 Antihistamines
113(3)
7.6 Mast Cell Stabilizers
116(2)
References
118(3)
8 Vitamins
121(14)
8.1 General Remarks
121(1)
8.2 Vitamin A
122(3)
8.3 The Vitamin B Complex
125(5)
8.4 Vitamin C--Ascorbic Acid
130(1)
8.5 Vitamin D--Calciferol
131(1)
8.6 Vitamin E--Tocopherol
131(1)
8.7 Vitamin K
132(1)
References
133(2)
9 Agents That Affect Blood Coagulation and Tissue Perfusion
135(18)
9.1 The Blood Clotting System
135(2)
9.2 Anticoagulants
137(2)
9.3 Thrombolytic and Fibrinolytic Agents
139(2)
9.4 Hemostatic Agents, Prophylaxis of Bleeding
141(2)
9.5 Agents That Increase Tissue Perfusion
143(5)
9.6 Vasoconstrictors
148(2)
References
150(3)
10 Pharmacology of Medications Affecting the Pupil and Intraocular Pressure
153(38)
10.1 The Autonomic Nervous System
153(7)
10.2 Parasympathomimetic Glaucoma Medications (Miotics)
160(5)
10.3 Parasympatholytic Medications
165(1)
10.4 Sympathomimetic Medications
166(4)
10.5 Dopaminergic Medication
170(1)
10.6 Direct Sympatholytic Medications
170(4)
10.7 Indirect Sympatholytic Medications
174(1)
10.8 Prostaglandins
174(1)
10.9 Carbonic Anhydrase Inhibitors
175(2)
10.10 Combinations of Antiglaucoma Medications
177(1)
10.11 Hyperosmotic Agents
178(2)
10.12 Other Antiglaucoma Medications
180(3)
References
183(8)
11 Medical Management of Glaucoma
191(40)
11.1 Definition and Classification of the Glaucomas
191(1)
11.2 Diagnosis of Glaucoma
192(8)
11.3 Primary Open-Angle Glaucoma
200(12)
11.4 Primary Angle-Closure Glaucoma
212(3)
11.5 Mixed Forms of Glaucoma
215(1)
11.6 Congenital (Developmental) Glaucoma
215(1)
11.7 The Secondary Glaucomas
215(6)
11.8 Absolute Glaucoma
221(1)
11.9 Retrobulbar Injection of Alcohol for the Seeing Eye
222(1)
11.10 Hypotony
222(1)
References
223(8)
12 The Orbit
231(22)
12.1 Introduction
231(1)
12.2 Orbital Infections
231(4)
12.3 Thyroid (Graves') Endocrine Orbitopathy
235(4)
12.4 Orbital Pseudotumor
239(2)
12.5 Vasculitic Diseases of the Orbit
241(1)
12.6 Sarcoidosis
242(1)
12.7 Neoplasms
242(6)
References
248(5)
13 The Eyelids
253(26)
13.1 Blepharitis
253(4)
13.2 Bacterial Infections
257(6)
13.3 Viral Infections
263(1)
13.4 Mycotic Infections
264(2)
13.5 Parasitic Infestations
266(1)
13.6 Allergy
267(1)
13.7 Itching, Pruritus
268(1)
13.8 Edema of the Eyelids
268(1)
13.9 Faulty Eyelid Position
269(1)
13.10 Faulty Eyelid Function
270(3)
13.11 Radiation Damage
273(1)
13.12 Neoplasms
274(1)
References
275(4)
14 The Lacrimal System
279(6)
14.1 Dacryoadenitis
279(1)
14.2 Canalicular Disease
280(1)
14.3 Nasolacrimal Duct Obstruction
281(1)
14.4 Dacryocystitis
282(2)
References
284(1)
15 The Conjunctiva
285(42)
15.1 Conjunctivitis
285(2)
15.2 Bacterial Conjunctivitis
287(5)
15.3 Oculoglandular Conjunctivitis
292(3)
15.4 Special Types of Infectious Conjunctivitis
295(4)
15.5 Viral Conjunctivitis
299(5)
15.6 Conjunctivitis in the Newborn
304(3)
15.7 Allergic Conjunctival Disease
307(5)
15.8 Conjunctival Hyperemia
312(2)
15.9 Conjunctival Diseases of Uncertain Etiology
314(6)
15.10 Conjunctival Tumors
320(1)
References
321(6)
16 Diseases of the Cornea
327(56)
16.1 Bacterial Keratitis
327(11)
16.2 Protozoal Keratitis
338(2)
16.3 Keratomycosis
340(2)
16.4 Viral Keratitis
342(10)
16.5 Keratitis of Various Etiologies
352(2)
16.6 Keratitis Due to Hypersensitivity
354(5)
16.7 Wetting Disorders
359(8)
16.8 Degenerations and Dystrophies
367(5)
16.9 Tumors
372(1)
References
373(10)
17 The Sclera
383(6)
17.1 Noninfectious Scleral Inflammation
383(3)
17.2 Infectious Scleral Inflammation
386(1)
References
386(3)
18 The Lens and Zonules
389(10)
18.1 Congenital Cataracts
389(1)
18.2 Cataracts in Systemic Disease
390(1)
18.3 Cataracts Due to Extraneous Causes
391(1)
18.4 Cataracts in Ocular Disease
392(1)
18.5 Cortisone Cataracts
392(1)
18.6 Age-Related (Senile) Cataract
393(1)
18.7 Prevention of After-Cataracts
394(1)
18.8 Subluxation and Luxation
395(1)
18.9 Microspherophakia
395(1)
References
395(4)
19 Inflammations of Uvea and Retina
399(52)
19.1 General Aspects
399(2)
19.2 Additional Diagnostic Procedures
401(4)
19.3 Treatment
405(7)
19.4 Specific Uveitis Entities
412(29)
19.5 Masquerade Syndromes
441(1)
19.6 Uveal Melanoma
442(1)
References
443(8)
20 Endophthalmitis
451(20)
20.1 Postoperative Endophthalmitis
451(11)
20.2 Endophthalmitis Associated with Filtering Blebs
462(2)
20.3 (Post-) Traumatic Endophthalmitis
464(1)
20.4 Metastatic or Endogenous Endophthalmitis
465(2)
References
467(4)
21 Noninflammatory Retinal Disease
471(42)
21.1 Retinal Vascular Occlusions
471(7)
21.2 Degenerations and Heredodegenerations (Dystrophies)
478(9)
21.3 Diabetic Retinopathy
487(6)
21.4 Retinopathy of Prematurity
493(2)
21.5 Proliferative Vitreoretinopathy
495(1)
21.6 Retinoblastoma
496(3)
References
499(14)
22 The Optic Nerve
513(14)
22.1 Inflammations and Demyelinating Diseases
513(2)
22.2 Ischemic Optic Neuropathy
515(3)
22.3 Compression Neuropathy
518(2)
22.4 Toxic and Nutritional Damage to the Optic Nerve
520(3)
22.5 Radiation Optic Neuropathy
523(1)
22.6 Traumatic Optic Neuropathy
523(1)
22.7 Hereditary Diseases
523(1)
References
524(3)
23 Parasitic Diseases, Zoonoses
527(20)
23.1 Diseases Caused by Threadworms (Nematodes)
527(11)
23.2 Diseases Caused by Tapeworms (Cestodes)
538(2)
23.3 Diseases Caused by Flukes (Trematoda)
540(1)
23.4 Leishmaniasis
541(1)
23.5 Ocular Diseases Caused by Insects
542(3)
References
545(2)
24 Trauma
547(16)
24.1 Mechanical Injuries
547(7)
24.2 Insect Stings
554(1)
24.3 Chemical Trauma
555(2)
24.4 Thermal Injury
557(1)
24.5 Injury Due to Ultraviolet Radiation
558(1)
24.6 Electrical Injury
559(1)
References
559(4)
25 Anomalies of Refraction and Motility, Headaches and Migraine, Functional (Hysterical) Visual Disturbances
563(16)
25.1 Myopia
563(2)
25.2 Amblyopia
565(1)
25.3 Strabismus
565(5)
25.4 Asthenopia
570(1)
25.5 Disorders of Accommodation
571(1)
25.6 Headaches and Migraine
571(4)
25.7 Functional (Hysterical) Visual Disturbances
575(1)
References
575(4)
26 Perioperative Medical Therapy
579(24)
26.1 Substances Used Specifically at Surgery
579(7)
26.2 Periocular Procedures
586(1)
26.3 Corneal Procedures
587(3)
26.4 Cataract Surgery
590(3)
26.5 Glaucoma Surgery
593(3)
26.6 Vitreoretinal Surgery
596(1)
26.7 Postoperative Complications
597(1)
References
598(5)
List of Abbreviations 603(6)
Drug Index 609(27)
General Index 636

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