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9783805585262

Frontiers in Celiac Disease

by
  • ISBN13:

    9783805585262

  • ISBN10:

    3805585268

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2008-05-01
  • Publisher: KARGER, S. PUBLISHERS INC
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List Price: $209.00

Summary

Few other fields in human biology have experienced such a tremendous progress as celiac disease has during the past few years. The contributors to 'Frontiers in Celiac Disease' are world-renowned opinion leaders who made these advances possible. Their expertise has been assembled here to provide a comprehensive overview of the current knowledge of the epidemiology, pathogenesis, clinical presentations, diagnosis and treatment of celiac disease. In addition, the stage is set for innovative strategies for preventive interventions and treatment alternatives to a gluten-free diet. A valuable reference for basic and translational scientists, this book also serves as a practical resource to healthcare professionals, including general practitioners, subspecialists, dieticians, nutritionists, and nurses and nurse practitioners. Students from different disciplines will find this book a helpful guide to expand and deepen their knowledge of celiac disease.

Table of Contents

Preface
Historical Perspective of Celiac Diseasep. 1
Natural History of Celiac Diseasep. 12
The Changing Clinical Presentation of Celiac Diseasep. 18
The Global Village of Celiac Diseasep. 23
HLA and Non-HLA Genes in Celiac Diseasep. 32
Twins and Family Contribution to Genetics of Celiac Diseasep. 46
Biochemistry and Biological Properties of Gliadin Peptidesp. 57
Innate Immunity and Celiac Diseasep. 66
Celiac Disease: Across the Threshold of Tolerancep. 82
The Role of the Intestinal Barrier Function in the Pathogenesis of Celiac Diseasep. 89
Diagnosis of Coeliac Disease. Open Questionsp. 99
Current Guidelines for the Diagnosis and Treatment of Celiac Diseasep. 107
Current Therapyp. 114
Update on the Management of Refractory Coeliac Diseasep. 123
The National Institutes of Health Consensus Conference Reportp. 133
Beyond Coeliac Disease Toxicity. Detoxified and Non-Toxic Grainsp. 139
Oral Glutenase Therapy for Celiac Spruep. 148
Inhibitors of Intestinal Barrier Dysfunctionp. 157
Development of a Vaccine for Celiac Diseasep. 172
Regulatory T Cells in the Coeliac Intestinal Mucosa. A New Perspective for Treatment?p. 181
Strategies for Prevention of Celiac Diseasep. 188
Towards Preventing Celiac Disease - An Epidemiological Approachp. 198
Animal Models of Celiac Diseasep. 210
Author Indexp. 217
Subject Indexp. 218
Table of Contents provided by Blackwell. All Rights Reserved.

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