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Epilepsy care traditionally focuses on seizures, yet for most epilepsy sufferers, other interictal factors such as mood, cognitive abilities, and treatment adverse effects most influence how they feel and function day to day.Epilepsy and the Interictal State is a practical and comprehensive text that covers quality of life issues, cognition and therapy, adverse effects of epilepsy treatments, mood state and psychiatric co-morbidity and general health aspects of epilepsy. Each chapter employs a standard structure providing background, epidemiology, pathophysiology, etiology, diagnosis, treatment, prognosis and further practical advice.From an international team of expert editors and contributors, Epilepsy and the Interictal State is a valuable resource for specialist epileptologists and neurologists, as well as for neurosurgeons, neurology nurses, psychiatrists, family physicians and general practitioners.
Erik K. St Louis, Department of Neurology, Mayo Clinic, Rochester, MN, USA
David M. Ficker, Department of Neurology, University of Cincinnati, Cincinnati, OH, USA
Terence J. O’Brien, Departments of Medicine and Neurology, The Royal Melbourne Hospital, The University of Melbourne, Parkville, Vic, Australia
List of contributors, ix
Foreword, xiii
Section I: Quality of life and the interictal state in epilepsy
1 Quality of life in epilepsy: the key importance of the interictal state, 3David M. Ficker
2 Comorbidities in epilepsy: range and impact, 7J. Layne Moore and John O. Elliott
3 Epilepsy, comorbidities, and consequences: implications for understanding and combating stigma, 15Rosemarie Kobau, Colleen K. DiIorio, Nancy J. Thompson, Yvan A. Bamps, and Erik K. St. Louis
Section II: Cognition and epilepsy
4 Causes and types of cognitive domain impairments in epilepsy, 29Impairment of consciousness in epilepsy, 31Luigi Maccotta, Clemente Vega, and R. Edward Hogan
Ictal cognitive impairments due to nonconvulsive status epilepticus, 38Elizabeth Waterhouse
Memory and dysexecutive impairments in epilepsy, 45Erik K. St. Louis and Ashley M. Enke
Attention deficit/hyperactivity disorder, disordered attention, and epilepsy, 63David W. Dunn and William G. Kronenberger
Behavioral and developmental disorders in epilepsy, 68Michael Smith and Esmeralda L. Park
5 Cognitive effects of epilepsy therapies, 74Beth A. Leeman and Kimford J. Meador
6 Autism and epilepsy, 88Vladimýr Komárek
7 Cognitive rehabilitation strategies in epilepsy, 94Cher Stephenson and Robert D. Jones
Section III: Adverse effects of epilepsy therapies
8 Adverse effects in epilepsy: recognition, measurement, and taxonomy, 103Frank G. Gilliam, Laura S. Snavely, and Piero Perucca
9 Clinically important antiepileptic drug interactions and their influence on adverse effects in epilepsy, 110Frank M.C. Besag and Philip N. Patsalos
10 Minimizing the adverse effects of epilepsy therapies: principles and practice, 120Erik K. St. Louis
11 Idiosyncratic adverse side effects of antiepileptic drugs: risk, prevention, and counseling, 127Mary L. Zupanc and Lily H. Tran
12 Antiepileptic drug therapy and fetal development, 136Frank J.E. Vajda
Section IV: Mood state, psychiatric comorbidity, and epilepsy
13 Mood state, anxiety, and psychosis in epilepsy, 147Michael Salzberg
14 The contribution of sleep and anxiety disorders to quality of life in people with epilepsy, 159Dee Snape, Ann Jacoby, and Gus Baker
15 Epilepsy and personality, 171Christopher Turnbull, Simon Jones, Sophia J. Adams, and Dennis Velakoulis
16 Psychogenic attacks and epilepsy, 183Bláthnaid McCoy and Selim R. Benbadis
Section V: General health and epilepsy 17
Obesity and epilepsy, 195Sandra J. Petty and Alison M. Pack
18 Epilepsy in the elderly: vascular disease, the aging brain, and selection of appropriate therapies, 203Katherine H. Noe and Joseph I. Sirven
19 Balance disorders and falls in epilepsy, 216Sandra J. Petty, Keith D. Hill, and John D. Wark
20 Bone health in epilepsy, 224Sandra J. Petty, and John D. Wark
21 Sleep and epilepsy, 230Irakli Kaolani and Erik K. St. Louis
22 Use of complementary and alternative medicine in epilepsy, 241Dana Ekstein and Steven C. Schachter
23 Epilepsy and alcohol and substance abuse, 252Ekrem Kutluay and Jonathan C. Edwards
24 Driving, employment, and related issues in epilepsy, 258Kristine Ziemba and Joe Drazkowski
Index, 267
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