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9780824740139

Separation Techniques in Clinical Chemistry

by ;
  • ISBN13:

    9780824740139

  • ISBN10:

    0824740130

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2003-05-28
  • Publisher: CRC Press

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Summary

This reference examines innovations in separation science for improved sensitivity and cost-efficiency, increased speed, higher sample throughput and lower solvent consumption in the assessment, evaluation, and validation of emerging drug compounds. It investigates breakthroughs in sample pretreatment, HPLC, mass spectrometry, capillary electrophoresis and therapeutic drug monitoring for improved productivity, precision, and safety in clinical chemistry, biomedical analysis, and forensic research. From saliva, hair, and biological samples to illegal drugs and toxins, Separation Techniques in Clinical Chemistry is a thorough single-source guide for analytical, organic, pharmaceutical, medicinal, physical, surface, and colloid chemists and biochemists; and upper-level undergraduate and graduate students in these disciplines.

Table of Contents

Preface iii
Contributors vii
Sample Pretreatment in Clinical Chemistry
1(102)
I. N. Papadoyannis
V. F. Samanidou
Separation Science in Therapeutic Drug Monitoring
103(36)
Zak K. Shihabi
The Impact of Chirality in Pharmacokinetics and Therapeutic Drug Monitoring
139(24)
Karla A. Moore
Barry Levine
HPLC in Bioavailability Examination
163(30)
Zdzislaw Chilmonczyk
Kamila Kobylinska
Hassan Y. Aboul-Enein
Validation of HPLC Analyses in Therapeutic Drug Monitoring
193(28)
Zdzislaw Chilmonczyk
Iwona Cendrowska
Hassan Y. Aboul-Enein
Analysis of Illicit Drugs with Chromatographic Methods
221(68)
M. J. Bogusz
Biogenic Amine Neurotransmitters: Their Importance and Measurement in Human Tissue and Body Fluids
289(32)
Adarsh M. Kumar
Clinical Applications of Affinity Chromatography
321(40)
William Clarke
David S. Hage
Immunoaffinity Chromatography in Clinical Analysis
361(28)
David S. Hage
William Clarke
Electrospray Tandem Mass Spectrometry in the Biochemical Genetics Laboratory
389(44)
Mohamed S. Rashed
Application of Thin-Layer Chromatography in Clinical Chemistry
433(56)
Jan Bladek
Slawomir Neffe
Applications of Capillary Electrophoresis in Clinical Analysis of Drugs
489(32)
Jacek Bojarski
Joanna Szymura-Oleksiak
Index 521

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