Sepsis and Organ Dysfunction

by Baue, Arthur E.; Berlot, G.; Gullo, A.; Vincent, J. L.

• ISBN13: 9788847000964
• ISBN10: 8847000963
• Format: Paperback
• Copyright: 2000-04-01
• Publisher: Springer Verlag

Summary

St. Louis Univ., MO. Papers from an unnamed conference of the Organ Failure Academy, via Battisti, Italy. Date is not cited. Discusses oxygen transport in sepsis, organ dysfunction and biohumoral mismatch in sepsis, and sepsis trials. For clinicians and researchers. Softcover.

Table of Contents

Introduction	p. 11
Sepsis and Organ Dysfunction. The Challenge Continues	p. 17
Oxygen Transport in Sepsis
Biochemical Regulation of the Microcirculation	p. 37
Oxygen Supply and Consumption in Tissues	p. 43
Ischaemia-Reperfusion in Sepsis	p. 49
Mechanism of Oxygen Extraction Defect in Septic Shock	p. 57
Organ Dysfunction and Biohumoral Mismatch in Sepsis
Gut Perfusion in Sepsis and Shock	p. 67
Pathophysiology of Encephalopathy	p. 77
Lung Dysfunction in the Early Phase of Sepsis	p. 85
The Kidney in Sepsis	p. 91
Pathophysiology of Liver Dysfunction in Sepsis	p. 103
Inflammatory Cells in Septic Shock	p. 107
Sepsis Trial
Revised Terminology on Sepsis	p. 115
The Epidemiology and Outcome of Patients with Sepsis: Clear as Mud	p. 123
Are there Useful New Markers of Sepsis?	p. 137
A Paradigm Shift: The Bidirectional Effect of Inflammation on Bacterial Growth	p. 145
Is the Dosing and Timing of the Intervention Adequate?	p. 155
Clinical Trials of Mediator-Targeted Therapy in Sepsis	p. 161
Index	p. 175
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