Sexual Differentiation of the Brain

by Matsumoto, Akira

• ISBN13: 9780849311659
• ISBN10: 0849311659
• Format: Hardcover
• Copyright: 2000-01-01
• Publisher: CRC Pr I Llc

Summary

Sexual difference in the brain has long been one of the more intriguing research areas in the field of neuroscience. This thorough and comprehensive text uncovers and explains recent neurobiological and molecular biological studies in the field of neuroscience as they relate to the mechanisms underlying sexual differentiation of the brain.Attempts have been made to clarify sex differences in the human brain using noninvasive techniques such as magnetic resonance imaging. Sexual Differentiation of the Brain thoroughly examines these techniques and findings, providing an up-to-date, comprehensive overview written by leading researchers in the field.Just a few of the topics addressed include genetic contributions to the sexual differentiation of behavior; in-vitro studies of the effects of estrogen on estrogen receptor-transfected neuroblastoma cells; and the evolution of brain mechanisms controlling sexual behavior. Other topics include sexual differentiation of neural circuitry in the hypothalamus; structural sex differences in the mammalian brain; and sexual differentiation of cognitive functions in humans.With its revealing and informative chapters, as well as provocative treatment of the subject matter, Sexual Differentiation of the Brain helps shed new light on one of the most fascinating areas of brain research.

Author Biography

Akira Matsumoto, Ph.D., is an associate professor in the Department of Anatomy, Juntendo University School of Medicine, Tokyo (Japan). Dr. Matsumoto received a B.S. degree (biology, 1968) and a Ph.D. degree (biology, 1974) from the University of Tokyo, Tokyo (Japan). He has served on the faculty of the Department of Anatomy, Juntendo University School of Medicine from 1974 to present. He received an International Society of Andrology Award (1993) and a Zoological Science Award (1997). He is a member of the Society of Neuroscience, the International Brain Research Organization, the International Society of Neuroendocrinology, the Society of Behavioral Neuroendocrinology, the International Society of Andrology, the Japanese Association of Anatomists, the Japanese Association of Endocrinology, the Japan Neuroscience Society, the Japanese Society for Comparative Endocrinology, and the Zoological Society of Japan.

Table of Contents

Sexual Differentiation of the Brain: A Historical Review	1	(10)
Yasumasa Arai
Genetic Contributions to the Sexual Differentiation of Behavior	11	(10)
Sonoko Ogawa
Donald W. Pfaff
In Vitro Study for Effects of Estrogen on Estrogen Receptor-Transfected Neuroblastoma Cells	21	(12)
Paola Agrati
Laura Bolzoni
Alessia Brusadelli
Paolo Ciana
Elena Marini
Clara Meda
Cesare Patrone
Michael C. Penlington
Giuseppe Pollio
Monica Rebecchi
Rodolfo H. Sialino
Elisabetta Vegeto
Adriana Maggi
Steroid Metabolism in the Brain: Role in Sexual Differentiation	33	(26)
Paola Negri-Cesi
Angelo Poletti
Luciano Martini
Flavio Piva
Estrogen in Gender-Specific Neural Differentiation	59	(24)
John B. Hutchison
Glial Cells Are Involved in Organizational and Activational Effects of Sex Hormones in the Brain	83	(12)
Luis Miguel Garcia-Segura
Gloria P. Cardona-Gomez
Jose Luis Trejo
Maria C. Fernandez-Galaz
Julie Ann Chowen
Sex Steroids and Weakly Electric Fish: A Model System for Activational Mechanisms of Hormone Action	95	(18)
Harold H. Zakon
Evolution of Brain Mechanisms Controlling Sexual Behavior	113	(18)
David Crews
Jon Sakata
Hormonal and Nonhormonal Mechanisms of Sexual Differentiation of the Zebra Finch Brain: Embracing the Null Hypothesis	131	(18)
Arthur P. Arnold
Sexual Differentiation of a Neuromuscular System	149	(26)
Scott E. Christensen
S. Marc Breedlove
Cynthia L. Jordan
Development of Sexually Dimorphic Forebrain Pathways	175	(28)
Richard B. Simerly
Sexual Differentiation of Neuronal Circuitry in the Hypothalamus	203	(26)
Akira Matsumoto
Yoshie Sekine
Shizuko Murakami
Yasumasa Arai
Structural Sex Differences in the Mammalian Brain: Reconsidering the Male/Female Dichotomy	229	(28)
James C. Woodson
Roger A. Gorski
Gonadal Hormones and Sexual Differentiation of Human Behavior: Effects of Psychosexual and Cognitive Development	257	(22)
Melissa Hines
Sexual Differentiation of Spatial Functions in Humans	279	(22)
Elizabeth Hampson
The Luteinizing Hormone-Releasing Hormone System in the Developing Monkey Brain	301	(18)
Ei Terasawa
Laurie A. Abler
Nancy M. Sherwood
Index	319