Signal Transduction: Principles, Pathways, and Processes

by Cantley, Lewis; Hunter, Tony; Sever, Richard; Thorner, Jeremy

• ISBN13: 9780879699017
• ISBN10: 0879699019
• Edition: 1st
• Format: Hardcover
• Copyright: 2014-05-31
• Publisher: Cold Spring Harbor Laboratory Press

Table of Contents

(preliminary)

Preface

Foreword
Edmond Fischer

I. GENERAL PRINCIPLES AND MECHANISMS

1. Signals and Receptors
Carl Henrik-Heldin, Benson Lu, Ron Evans, and Silvio Gutkind

2. General Principles and Mechanisms of Protein Regulation in Signal Transduction
Michael J. Lee and Michael B. Yaffe

3. Second Messengers
Alexandra Newton and Susan Taylor

4. Signaling Networks: Computational Capabilities and Decision-making
Evren U. Azeloglu and Ravi Iyengar

II. PATHWAYS/ROAD MAPS

MAP Kinase Pathways
Deborah Morrison
PI3K-PKB/Akt Pahway Signaling
Brian A. Hemmings & David F. Restuccia
mTOR Signaling
Mathieu Laplante and David M. Sabatini
Calcium Signaling
Martin D. Bootman
AC-cAMP
Paolo Sassone-Corsi
Wnt Signaling Pathway
Roel Nusse
Hedgehog Signaling
Philip W. Ingham
Notch Pathway
Raphael Kopan
Signaling by the TGF Superfamily
Jeff Wrana
JAK/STAT Pathway
Douglas A. Harrison
Toll-like Receptor Signaling
Kian Huat Lim and Louis Staudt
Immunoreceptor Signaling
Lawrence E. Samelson
Signaling by Nuclear Receptors
Richard Sever & Christopher K. Glass
Hippo Pathway
Kieran F. Harvey and Iswar K. Hariharan

III. SIGNALING PROCESSES

5. Signaling to the G1 Cell Cycle
Robert J. Duronio and Yue Xiong
6. Signaling Pathways that Regulate Cell Division
Nicholas Rhind and Paul Russell
7. Cell Growth and Metabolism
Patrick S. Ward and Craig B. Thompson
8. Signal Transduction and the Regulation of Cell Migration
Peter Devreotes and Rick Horwitz
9. Signaling Pathways in Cell Polarity
Luke M. McCaffrey and Ian G. Macara
10. Signaling Mechanisms Controlling Cell Fate and Embryonic Patterning
Norbert Perrimon, Chrysoula Pitsouli, and Ben-Zion Shilo
11. Signaling in Development 2
Benjamin Neel and Senthil Muthuswarmy
12. Signaling by Sensory Receptors
David Julius and Jeremy Nathans
13. Synaptic Signaling in Learning and Memory
Mary B. Kennedy
14. Intracellular Calcium Signaling
Ivana Y. Kuo and Barbara E. Ehrlich
15. Organismal Carbohydrate and Lipid Homeostasis
D. Graham Hardie
16. Innate Immunity and Inflammation
Kim Newton and Vishva Dixit
17. Lymphocyte Activation/Behavior
Doreen Cantrell
18. Vertebrate Reproduction
Sally Kornbluth and Rafael Fissore
19. Stress Responses
Gökhan Hotamisligil and Roger J. Davis
20. Cell Death Signaling
Douglas R. Green and Fabien Llambi
21. Cancer
Joan S. Brugge
22. Subversion of Cell Signaling by Pathogens
Kim Orth and Neal Alto

Index