Simultaneous EEG and fMRI Recording, Analysis, and Application

by Ullsperger, Markus; Debener, Stefan

• ISBN13: 9780195372731
• ISBN10: 0195372735
• Edition: 1st
• Format: Hardcover
• Copyright: 2010-05-28
• Publisher: Oxford University Press

Summary

One of the major challenges in science is to study and understand the human brain. Numerous methods examining different aspects of brain functions have been developed and employed. To study systemic interactions brain networks in vivo, non-invasive methods such as electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) have been used with great success. However, each of these methods can map only certain, quite selective aspects of brain function while missing others; and the inferences on neuronal processes and information flow are often rather indirect. To overcome these shortcomings of single methods, researchers have attempted to combine methods in order to make optimal use of their advantages while compensating their disadvantages. Hence, it is not surprising that soon after the introduction of fMRI as a neuroimaging method the possibilities of combinations with EEG have been explored. This book is intended to aid researchers who plan to set up a simultaneous EEG-fMRI laboratory and those who are interested in integrating electrophysiological and hemodynamic data. As will be obvious from the different chapters, this is a dynamically developing field in which several approaches are being tested, validated and compared. Currently, there is no one best solution for all problems available, but many promising techniques are emerging. This book shall give a comprehensive overview of these techniques. In addition, it points to open questions and directions for future research.

Author Biography

Robert T. Knight, MD, Evan Rauch Professor of Neuroscience, Director, Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA

Table of Contents

Contributors

Physiological basics of EEG and fMRI

The relationship of synaptic events and macroscopic recordings

Physiological basics of the BOLD signal

Why should we combine different neuroimaging methods

Technical basics of recording simultaneous EEG-fMRI

Recording EEG signals inside the MRI

Scanning strategies for simultaneous EEG-fMRI recordings

Removal of artifacts from EEG recordings

Influence of EEG equipment on MRI image quality

Multimodal data integration

Using ICA for the analysis of EEG data

Using ICA for the analysis of fMRI data

EEG-informed fMRI analysis

Fusion of EEG and fMRI by parallel group ICA

Joint EEG-fMRI ICA decomposition

Estimating the hemodynamic response using EEG

Integration of separately recorded EEG/MEG and fMRI

Analyzing functional and effective connectivity with EEG and MEG

Analyzing functional and effective connectivity with fMRI

Applications

Linking band-limited cortical activity with fMRI and behavior

Clinical applications: Epilepsy

Index

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