Sleep and Sleep Disorders

by Lader, Macolm; Cardinali, Daniel P.; Pandi-Perumal, S. R.; Lader, Malcolm Harold

• ISBN13: 9780387276816
• ISBN10: 0387276815
• Format: Hardcover
• Copyright: 2005-08-01
• Publisher: Landes Bioscience

Summary

Many recent discoveries in both laboratory and clinical settings have greatly increased our understanding of sleep medicine and the relevant psychopharmacology. This timely book serves to present updated information about the neuropsychopharmacology of sleep as this field enters mainstream psychiatry, neurology and medicine This volume has assembled articles that summarize and review carefully, a chosen selection of the latest discoveries concerning sleep medicine, sleep physiology and sleep pharmacology. Outstanding contributions have been sought from acknowledged experts in their respective fields. The goal of the volume is to present the more recent developments and advances in the fields of sleep and neuropsychopharmacology, as well as to provide a context for considering them both in depth and from multidisciplinary perspectives. This volume brings together the collective expertise of clinicians and basic researchers who represent a range of interests in neuroscience, neuropharmacology, sleep physiology, and biological rhythms. Presenting a thoughtful balance of basic experimental and clinical facts and viewpoints, this book will serve as a foundation for understanding, and ultimately treating, sleep disorders.

Table of Contents

Basic Pharmacology

GABAA Receptor Subtypes in Sedation and Hypnosis

Sleep Hippocampal Theta Rhythm and Sensory Processing

Monoaminergic Mechanisms in the Regulation of Sleep-Wakefulness: Special Emphasis on Preoptic Noradrenergic System

REM Sleep Function and Brain Monoamine Regulation: An Application of the Search Activity Concept

Role of Wakefulness Area in the Brainstem Reticular Formation in Regulating Rapid Eye Movement Sleep

The Mechanistic Relationship between NREM Sleep and Anesthesia

Chronopharmacology

Time-Dependent Psychotropic Drug Effects Hints of Pharmacochronomics, Broader than Circadian Time Structures

Melatonin Interaction with Bz-Gabaa Receptors: Implications for Sleep Induction

Melatonin: A Chronobiotic that Not Only Shifts Rhythms

Melatonin and Human Sleep

Melatonin Efficacy to Treat Circadian Alterations of Sleep in Alzheimer's Disease

Pharmacotherapy for Seasonal Affective Disorder

Use and Discontinuation of Hypnosedative Medications

Clinical Pharmacology

Long-Term Use of Sleeping Pills in Chronic Insomnia

Risks of Chronic Hypnotic Use

Effects of Psychotropics on Driving Performance

Diagnosis, Pathophysiology and Treatment of Hypersomnias

Chronic Disease and Sleep Architecture Pharmacotherapeutic Considerations

Benzodiazepines for Sedation in Infants and Children

The Pharmacological Management of Fatigue and Sleepiness in Affective Disorders

Next-Day Residual Effects of Sleeping Medications on Driving Ability: A Review of the Literature

Sleep and Pain

Head Injuries and Sleep

Psychopharmacological Management of Restless Legs Syndrome and Periodic Limb Movements in Sleep

A Comparison of Visual Analog Scale and Categorical Ratings in Assessing the Patient's Estimate of Sleep Quality

The Pharmacostrategy of Treating Sleep Disorders in Parkinsonism

The Neuropharmacology of Nightmares

The Night Eating Syndrome

Drug Effects on Dreaming

Sleep Problems in Primary Care

SSRIs and Sleep in Man

Sleep and Antipsychotic Drugs in Schizophrenia Patients

Sleep and Epilepsy: From Interrelationships to Influence of Antiepileptic Drugs

Herbal Medicines and Sleep

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