Spinal Cord Injury

by Verhaagen; McDonald

• ISBN13: 9780444521378
• ISBN10: 0444521372
• Edition: 1st
• Format: Hardcover
• Copyright: 2012-11-21
• Publisher: Elsevier Science

Summary

Spinal Cord Injuries, the newest volume in the Handbook of Clinical Neurology series, offers a comprehensive and detailed overview of the rapidly evolving science and treatment of spinal cord injury. Advances in neuroimaging, surgical treatment and application of electrical stimulation are dramatically impacting the treatment and outcome of these injuries. It provides a clear introduction to the core science of spinal cord injury, as well as to exciting research investigating new treatment options. Coverage includes brain-machine interfaces, transcranial stimulation, new pharmacological strategies, use of olfactory ensheathing cells, stem cells and precursor cells, gene therapy and molecular target discovery. This volume is a great resource for neuroscience and clinical neurology research specialists and practicing neurologists seeking a clear reference to the science and treatment of spinal cord injury. *Comprehensive coverage of the latest scientific understanding of spinal cord injuries *Detailed coverage of current treatment best practices and potential future treatments *Connects leading edge research programs to future treatment opportunities

Table of Contents

Developmental and Anatomical Perspectives

Development and maturation of the spinal cord: implications of molecular and genetic defects

Anatomy and biomechanics of the spinal column and cord

Diagnosis and Prognosis

Clinical diagnosis and prognosis following spinal cord injury

Clinical neurophysiology in the prognosis and monitoring of traumatic spinal cord injury

Concepts of aging with paralysis: implications for recovery and treatment

Advanced MRI strategies for assessing spinal cord injury

Acute Spinal Cord Injury: Medical, Surgical and Rehabilitative Management

Advances in the management of spinal cord and spinal column injuries

Spinal cord injuries in children and adolescents

The changing landscape of spinal cord injury

Surgical treatments to restore function control in spinal cord injury

Advances in the rehabilitation management of acute spinal cord injury

Spasticity

Disordered cardiovascular control after spinal cord injury

New concepts in the prevention of pressure sores

Functional electrical stimulation for bladder, bowel and sexual function

Evidence based therapy for recovery of function after spinal cord injury

Functional electrical stimulation: restoration of respiratory function

Spinal cord stimulation: therapeutic benefits and movement generation after spinal cord Injury

Promoting optimal functioning in spinal cord injury: the role of rehabilitation psychology

Chronic Spinal Cord Injury - The Changing Perspective of Neurorestorative Rehabilitation, Activity-Based and Surgical Restoration Therapies

The changing field of rehabilitation: optimizing spontaneous regeneration and functional recovery

The longitudinal spinal cord injury: lessons from intra spinal plexus, cauda equina and medullary conus lesions

Post-traumatic syringomyelia

Post-traumatic deformity: prevention and management

Preclinical Research - Bridging the Gap Between Bench and Bedside

Spinal cord injury clinical trials: translational process, review of past and proposed acute trials with reference to recommended trial guidelines

Translating preclinical approaches into human application

Translational spinal cord injury research: preclinical guidelines and challenges

Brain-machine interfaces and transcranial stimulation: future implications for directing functional movement and improving function after spinal injury in humans

Approaches to repairing the damaged spinal cord: overview

Limiting spinal cord injury by pharmacological intervention

Harmful and beneficial effects of inflammation after spinal cord injury: potential therapeutic implications

Defeating inhibition of regeneration by scar and myelin components

Realising the maximum potential of Schwann cells to promote recovery from spinal cord injury

Repair of CNS lesions by transplantation of olfactory ensheathing cells

Cell transplantation: stem cells and precursor cells

Gene therapy, neurotrophic factors and spinal cord regeneration

Scaffolds to promote spinal cord regeneration

Molecular target discovery for neural repair in the functional genomics era

Combination therapies

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