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9781405134903

Statistics at Square Two Understanding Modern Statistical Applications in Medicine

by
  • ISBN13:

    9781405134903

  • ISBN10:

    1405134909

  • Edition: 2nd
  • Format: Paperback
  • Copyright: 2006-06-06
  • Publisher: BMJ Books
  • Purchase Benefits
List Price: $52.00

Summary

Updated companion volume to the ever popular Statistics at Square One (SS1)Statistics at Square Two, Second Edition, helps you evaluate the many statistical methods in current use. Going beyond the basics of SS1, it covers sophisticated methods and highlights misunderstandings. Easy to read, it includes annotated computer outputs and keeps formulas to a minimum.Worked examples of methods such as multiple and logical regression reinforce the text. Each chapter concludes with exercises to stimulate learning.All those who need to understand statistics in clinical research papers and apply them in their own research will value this compact and coherent guide.

Author Biography

M J Campbell, Professor of Medical Statistics, University of Sheffield, UK

Table of Contents

Preface viii
Models, tests and data
1(9)
Basics
1(1)
Models
2(1)
Types of data
3(1)
Significance tests
4(1)
Confidence intervals
5(1)
Statistical tests using models
6(1)
Model fitting and analysis: confirmatory and exploratory analyses
6(1)
Computer-intensive methods
7(1)
Bayesian methods
7(1)
Missing values
7(1)
Reporting statistical results in the literature
8(1)
Reading statistics in the literature
9(1)
Multiple linear regression
10(22)
The model
10(1)
Uses of multiple regression
11(1)
Two independent variables
11(5)
Interpreting a computer output
16(6)
Multiple regression in action
22(1)
Assumptions underlying the models
23(2)
Model sensitivity
25(2)
Stepwise regression
27(1)
Reporting the results of a multiple regression
28(1)
Reading the results of a multiple regression
28(4)
Logistic regression
32(21)
The model
32(2)
Uses of logistic regression
34(1)
Interpreting a computer output: grouped analysis
35(5)
Logistic regression in action
40(1)
Model checking
41(2)
Interpreting computer output: ungrouped analysis
43(2)
Case--control studies
45(1)
Interpreting computer output: unmatched case--control study
45(2)
Matched case--control studies
47(1)
Interpreting computer output: matched case--control study
47(2)
Conditional logistic regression in action
49(1)
Reporting the results of logistic regression
50(1)
Reading about logistic regression
50(3)
Survival analysis
53(14)
Introduction
53(1)
The model
54(2)
Uses of Cox regression
56(1)
Interpreting a computer output
56(2)
Survival analysis in action
58(1)
Interpretation of the model
59(1)
Generalisations of the model
59(1)
Model checking
60(2)
Reporting the results of a survival analysis
62(1)
Reading about the results of a survival analysis
63(4)
Random effects models
67(17)
Introduction
67(1)
Models for random effects
68(1)
Random vs fixed effects
69(1)
Use of random effects models
69(3)
Random effects models in action
72(2)
Ordinary least squares at the group level
74(2)
Computer analysis
76(4)
Model checking
80(1)
Reporting the results of random effects analysis
81(1)
Reading about the results of random effects analysis
81(3)
Other models
84(14)
Poisson regression
84(5)
Ordinal regression
89(3)
Time series regression
92(3)
Reporting Poisson, ordinal or time series regression in the literature
95(1)
Reading about the results of Poisson, ordinal or time series regression in the literature
96(2)
Appendix 1: Exponentials and logarithms
98(2)
Logarithms
98(2)
Appendix 2: Maximum likelihood and significance tests
100(9)
Binomial models and likelihood
100(2)
Poisson model
102(1)
Normal model
102(2)
Hypothesis testing: LR test
104(1)
Wald test
105(1)
Score test
106(1)
Which method to choose?
106(1)
Confidence intervals
107(2)
Appendix 3: Bootstrapping and variance robust standard errors
109(8)
Computer analysis
111(2)
The bootstrap in action
113(1)
Robust or sandwich estimate SE
113(2)
Reporting the bootstrap and robust SEs in the literature
115(2)
Appendix 4: Bayesian methods
117(2)
Reporting Bayesian methods in the literature
118(1)
Answers to exercises 119(4)
Glossary 123(6)
Index 129

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