Stem Cells in the Nervous System

by Gage, Fred H.; Bjorklund, A.; Prochiantz, A.; Christen, Y.

• ISBN13: 9783540205586
• ISBN10: 3540205586
• Format: Hardcover
• Copyright: 2004-05-01
• Publisher: Springer Verlag

Summary

After 40 years of research, scientists have confirmed that persistent neurogenesis occurs in the adult mammalian brain. The obvious next question is: "Are the newly generated neurons functional?" If so, "What are the functions of these new neurons?" This volume intends to clarify both questions by providing the latest data available.

Table of Contents

Neurogenesis in Adult Brain: Understanding Its Mechanism and Regulation
X. Zhao, D. Schaffer, and F.H. Gage	1	(24)
The Logic of Neural Cell Lineage Restiction: Neuropoiesis Revisited
D.J. Anderson, L. Lo, M. Zirlinger, G. Choi, and Q. Zhou	25	(18)
Astrocytic Nature of Adult Neural Stem Cells in Vivo
A. Alvarez-Buylla, F. Doetsch, B. Seri, and J.M. Garcia-Verdugo	43	(14)
What is the Functional Role of New Neurons in the Adult Dentate Gyrus?
G. Kempermann and L. Wiskott	57	(10)
Do Forebrain Neural Stem Cells Have a Role in Mammalian Olfactory Behavior?
E. Enwere and S. Weiss	67	(16)
Converting ES Cells Into Neurons
A. Smith	83	(12)
Stem Cell Infidelity
J. Frisén	95	(14)
The Importance of CNS Stem Cells in Development and Disease
R. Mc Kay	109	(8)
In vivo Properties of In Vitro-Propagated Neural Stem Cells After Transplantation to the Neonatal and Adult Rat Brain
U. Englund and A. Björklund	117	(22)
Neurogenesis in Stroke and Epilepsy
Z. Kokaia, A. Arvidsson, C. Ekdahl, and O. Lindvall	139	(8)
The Incorrect Use of Transcription Factors: A Key to your (Stem) Cells?
A. Prochiantz, G. Mainguy, L. Sonnier, I. Caillé, B. Lesaffre, M. Volovitch, and A. Joliot	147	(10)
Leukemia and Leukemic Stem Cells
C.H.M. Jamieson, E. Passegue, and I.L. Weissman	157	(26)
Subject Index	183