Stroke

by Edlow, Jonathan A.

• ISBN13: 9780313342417
• ISBN10: 0313342415
• Edition: 1st
• Format: Hardcover
• Copyright: 2008-05-01
• Publisher: GREENWOOD PUBLISHING GROUP

Summary

Diseases have a history, and understanding that history helps us understand how best to treat and control disease today. Today's students are confronted with a panoply of often-frightening illnesses and afflictions - the Biographies of Disease series provides students with the information that they need to understand the origin of various maladies, how they impact contemporary society, and how doctors and researchers from around the world are fighting to devise treatments to alleviate or cure these diseases. This volume, Stroke, covers a common affliction that comes in many different forms, which can be fatal or leave the patient disabled, and which strikes a surprising number of younger people.

Table of Contents

Series Foreword	p. ix
Preface	p. xi
Introductory Concepts and Definitions	p. 1
Pathophysiology and Risk Factors for Stroke	p. 11
Embolic Stroke Resulting from Heart Disease	p. 13
Atherosclerosis	p. 14
Genetic Factors	p. 16
Elevated Lipids	p. 16
Small-Vessel Disease	p. 16
Blood Coagulation	p. 17
Hemorrhagic Stroke	p. 20
Symptoms: Am I Having a Stroke?	p. 25
Abrupt Onset	p. 25
Neurological Dysfunction in a Single Arterial Territory	p. 26
Duration of Symptoms Lasts Greater than Twenty-Four Hours	p. 26
Specific Symptoms	p. 27
Diagnosis of Stroke	p. 35
General Treatment of Stroke	p. 51
ABCs	p. 51
Blood Pressure Control	p. 52
Guidelines for Elevated Blood Pressure	p. 56
Temperature	p. 56
Pain and Anxiety	p. 57
Blood Sugar	p. 57
Stroke Centers	p. 58
Specific Treatment of Ischemic Stroke	p. 63
Fibrinolytic (Thrombolytic) Treatment	p. 63
Fibrinolytic Treatment Beyond Three Hours from Onset of Symptoms	p. 70
Anticoagulation Drug Therapy	p. 70
Anti-Platelet Drug Therapy	p. 72
Neuroprotective Agents	p. 72
Lipids	p. 73
Treatment of Hemorrhagic Stroke	p. 75
General Issues	p. 75
Surgery	p. 78
Procoagulant Medications	p. 79
Interventions to Reduce ICP	p. 80
Amyloid Angiopathy	p. 80
Hypertensive Bleed	p. 81
Coagulopathy-Associated Bleed	p. 82
Intracranial Aneurysm	p. 83
AVM and Other Vascular Abnormalities	p. 87
Venous Sinus Thrombosis	p. 88
Arterial Dissection	p. 89
Vasculitis	p. 90
Subdural and Epidural Hemorrhage	p. 91
Long-Term Outcomes	p. 93
Preventing Stroke	p. 101
Lifestyle Modifications	p. 102
Hypertension (High Blood Pressure)	p. 104
Diabetes	p. 105
Blood Lipids	p. 107
Atrial Fibrillation	p. 108
Other Cardio-embolic Sources of Clot	p. 110
Anti-Platelet Medications	p. 110
Asymptomatic Carotid Stenosis	p. 111
Elevated Homocysteine Levels	p. 112
Hypercoagulable States	p. 112
PFO	p. 112
Intracranial Aneurysm	p. 113
Prevention of Hemorrhagic Stroke	p. 116
TIA: A Golden Opportunity at Stroke Prevention	p. 119
New Horizons: Bats and Snakes	p. 127
Stroke Systems of Care	p. 128
New Medical Approaches to Stroke Treatment	p. 128
New Surgical and Interventional Endovascular Approaches	p. 135
Conclusions	p. 139
Timeline	p. 141
Glossary	p. 147
Bibliography	p. 157
Index	p. 159
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