Stroke : Pathophysiology, Diagnosis, and Management

by Mohr, Choi, Grotta, Weir & Wolf

• ISBN13: 9780443066009
• ISBN10: 0443066000
• Edition: 4th
• Format: Hardcover
• Copyright: 2004-03-17
• Publisher: Churchill Livingstone

Summary

First published in 1986 under the editorial direction of Dr. Henry J.M. Barnett, this encyclopedic, yet readable text has served as a "one-stop shop" for generations of practitioners seeking authoritative coverage of the scientific and clinical aspects of stroke. The 4th Edition features a new editorial team led by former co-editor Dr. J.P. Mohr, offering updated and expanded coverage of epidemiology and prevention, clinical manifestations, diagnosis, specific medical diseases related to stroke, pathophysiology, and medical and surgical therapy. Explains the mechanisms of stroke and stroke-related diseases. Provides comprehensive clinical guidancefrom recognizing the clinical manifestations of stroke and using the latest laboratory and imaging studies to arrive at a diagnosis to medical and surgical treatment planning. Features a new editorial team led by former co-editor Dr. J.P. Mohr. Devotes a new section to Epidemiology and Prevention, with chapters on distribution, risk factors and prevention, and outcomes. Offers fresh perspectives from new authors on the latest advances in imaging, addressing functional neuroimaging, fast MRI, and more. Includes an expanded Pathophysiology section, with new chapters on excitotoxicity, apoptosis, inflammation, intracellular signaling, recovery of function, and more. Contains a reorganized and expanded Therapy section, with separate subsections on medical therapies (including new anticoagulants and neuroprotection agents) and surgical therapies (including new procedures for prevention and repair of stroke damage). With over 130 additional contributors.

Table of Contents

Epidemiology and Prevention

Distribution of Stroke

Risk Factors for Stroke and Stroke Prevention

Outcome Following Stroke

Clinical Manifestations

Classification of Ischemic Stroke

Internal Carotid Artery Disease

Anterior Cerebral Artery Disease

Middle Cerebral Artery Disease

Posterior Cerebral Artery Infarcts

Anterior Choroidal Artery Infarcts

Vertebrobasilar Infarction

Lacunes

Cerebral Venous Thrombosis

Parenchymatous Hemorrhage

Aneurysmal Subarachnoid Hemorrhage

Brain Vascular Malformations

Spinal Cord Ischemia

Diagnostic Studies

Overview of Laboratory Studies

Computed Tomography-Based Evaluation of Cerebrovascular Disease

Magnetic Resonance Imaging

Conventional Angiography

Ultrasonography

Single-Photon Emission Computed Tomography

Specific Medical Diseases and Stroke

Arterial Dissections

Collagen Vascular and Infectious Diseases

Moyamoya Disease

Fibromuscular Dysplasia

Migraine

Hypertensive Encephalopathy

Vascular Cognitive Impairment and Dementia

Atherosclerotic Disease of the Aortic Arch

Binswangers Disease

Cadasil

Cerebral Amyloid Angiopathy

Coagulopathies

Stroke with Substance Abuse

Cardiac Diseases, Including Patent Foramen Ovale

Pathophysiology

Vascular Biology and Atherosclerosis

Thrombosis and Thrombolysis

Cerebral Blood Flow and Metabolism in Cerebrovascular Disease

Histopathology of Cerebral Ischemia

Excitotoxicity

Apoptosis

White Matter Injury

Inflammation

Intracellular Signaling: Mediators and Protective Responses

Recovery of Function

Therapy

Medical Therapy

Prehospital and Emergency Department Care of the Acute Stroke Patient

Intravenous Thrombolysis for Acute Stroke

Intra-arterial Thrombolysis for Acute Stroke

Antithrombotic Therapy for Acute Stroke

General Stroke Management and Stroke Units

Critical Care of the Acute Stroke Patient

Pharmacologic Modification of Acute Stroke (Neuroprotection)

Treatment of "Other" Stroke Etiologies

Medical Therapy of Intracerebral and Intraventricular Hemorrhage

Rehabilitation and Recovery of the Stroke Patient

Antiplatelet Therapy for Secondary Stroke Prevention

Medical Management of Intracranial and Extracranial Atherosclerosis

Stenting of Intracranial and Extracranial Arterial Stenoses

Secondary Prevention of Cardioembolic Stroke

Clinical Trials for Stroke B. Surgical Therapy

Inherited Vascular Diseases of Neurosurgical Significance

Intracranial Hemorrhage

Intraventricular Hemorrhage

Symptomatic Carotid Occlusive Disease

Asymptomatic Carotid Occlusive Disease

Intracranial Aneurysms

Arteriovenous Malformations

Cavernous and Venous Malformations

Dural Arteriovenous Malformations

Moyamoya Disease: Surgical Aspects

Spinal Vascular Malformations

Cerebral Vasospasm

Extracranial-Intracranial Bypass for Cerebral Ischemia

Cerebral Infarction: Surgical Treatment

Cerebellar Infarction and Hemorrhage

Nontraumatic Intracranial Arterial Dissection

Interventional Neuroradiologic Therapy

Standards for Surgical Care of Stroke, Circa 2000

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