Structure and Dynamics of Biomolecules Neutron and Synchrotron Radiation for Condensed Matter Studies

by Fanchon, Eric; Geissler, Erik; Hodeau, Jean-Louis; Regnard, Jean-René; Timmins, Peter A.

• ISBN13: 9780198504528
• ISBN10: 0198504527
• Format: Paperback
• Copyright: 2000-04-06
• Publisher: Oxford University Press

Summary

This manual describes the principles behind various types of experiments on biological samples using sychrotron radiation or neutrons, and it provides the technical understanding needed for interpreting the data collected.

Table of Contents

The plates section falls between pages 208-209
List of abbreviations	xi
List of contributors	xiii
Protein structure
Challenges in structural molecular biology: genomics in three dimensions	3	(11)
J. Janin
Data collection and reduction methods	14	(22)
A.G.W. Leslie
Experimental determination of structure factor phases in biocrystallography	36	(43)
R. Fourme
W. Shepard
M. Schiltz
M. Ramin
R. Kahn
Electron density---calculation, modification and interpretation	79	(23)
M. Kjeldgaard
Neutron crystallography of biological molecules	102	(14)
E. Pebay-Peyroula
D. Myles
Reactions in crystals and time-resolved crystallography	116	(8)
I. Schlichting
Local structure of metalloproteins at atomic resolution by XAFS	124	(17)
S.S. Hasnain
Dynamics of proteins
Molecular dynamics	141	(20)
M.J. Field
Inelastic and quasielastic neutron scattering: complementarity with biomolecular simulation	161	(20)
J.C. Smith
Diffuse X-ray scattering from molecular crystals	181	(18)
D.S. Moss
G.W. Harris
A. Wostrack
Solutions and partially ordered systems
Small-angle X-ray scattering by solutions of biological macromolecules	199	(39)
P. Vachette
D. Svergun
Small-angle neutron scattering	238	(13)
G. Zaccai
Structure and dynamics of biological membranes	251	(21)
G. Buldt
R. Schlesinger
E. Pebay-Peyroula
H.J. Sass
Fibre and muscle diffraction	272	(33)
J.M. Squire
Selected topics
Biological spectroscopy using low energy (VUV/UV) synchrotron radiation	305	(33)
G.R. Jones
I.H. Munro
X-ray microscopy	338	(15)
C.J. Buckley
Crystallography of viruses and very large macromolecules	353	(14)
D.I. Stuart
J.M. Grimes
E.E. Fry
The quest for high resolution phasing for large macromolecular assemblies exhibiting severe non-isomorphism, extreme beam sensitivity and no internal symmetry	367	(23)
A. Yonath
Nuclear spin contrast variation studies on macromolecular complexes	390	(17)
H.B. Stuhrmann
Index	407