Structure-based Study of Viral Replication (Book with CD-ROM)

by Cheng, R. Holland

• ISBN13: 9789812704054
• ISBN10: 9812704051
• Edition: 1st
• Format: Hardcover
• Copyright: 2008-01-01
• Publisher: World Scientific Pub Co Inc

Summary

This book addresses the innovative themes in characterizing the cellular membrane platforms and intracellular networking, as well as the architectural aspects of cell compartments mediated by the entry and replication cycles of viruses. The instrumentation of modern molecular and cellular biology provides a potent array of wave packets to image, detect and manipulate major dynamics of macromolecular and subviral assemblies as in the host cellular context.

Table of Contents

List of Contributors	p. ix
Human Rhinovirus Cell Entry and Uncoating	p. 1
Role of Lipid Microdomains in Influenza Virus Multiplication	p. 43
Functions of Integrin ¿2ß1, A Collagen Receptor, in the Internalization of Echovirus 1	p. 63
Entry Mechanism of Murine and SARS Coronaviruses - Similarity and Dissimilarity	p. 77
Hepatitis Viruses, Signaling Events and Modulation of the Innate Host Response	p. 91
Virus-Cell Interaction of HCV	p. 125
RNA Replication of Hepatitis C Virus	p. 151
Structure and Dynamics in Viral RNA Packaging	p. 173
Rational Design of Viral Protein Structures with Predetermined Immunological Properties	p. 199
Bioinformatics Resources for the Study of Viruses at the Virginia Bioinformatics Institute	p. 267
Virus Architecture Probed by Atomic Force Microscopy	p. 289
Filovirus Assembly and Budding	p. 311
Challenges in Designing HIV Env Immunogens for Developing a Vaccine	p. 327
Insights into the Caliciviridae Family	p. 381
Mathematical Approaches for Stoichiometric Quantification in Studies of Viral Assembly and DNA Packaging	p. 401
Virus-like Particles of Fish Nodavirus	p. 449
The Assembly of the Double-Layered Capsids of Phytoreoviruses	p. 463
Structure and Assembly of Human Herpesviruses: New Insights From Cryo-Electron Microscopy and Tomography	p. 483
Human Papillomavirus Type 16 Capsid Proteins: Immunogenicity and Possible Use as Prophylactic Vaccine Antigens	p. 517
Chimeric Recombinant Hepatitis E Virus-like Particles Presenting Foreign Epitopes as a Novel Vector of Vaccine by Oral Administration	p. 539
Nucleocapsid Protein of Hantaviruses (Bunyaviridae): Structure and Functions	p. 553
Astrovirus Replication: An Overview	p. 571
DNA Vaccines against Viruses	p. 597
Life Cycles of Polyomaviridae - DNA Tumor Virus	p. 609
Index	p. 631
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