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9780534252779

Student Companion for Fairbanks/Andersen's Genetics The Continuity of Life

by ;
  • ISBN13:

    9780534252779

  • ISBN10:

    053425277X

  • Format: Paperback
  • Copyright: 1999-06-18
  • Publisher: Cengage Learning
  • View Upgraded Edition

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Summary

For quite some time textbooks have steered the teaching of genetics down a fairly narrow path - transmissions genetics first, followed by molecular genetics. In Genetics: The Continuity of Life, Fairbanks and Andersen modernize the study of genetics for students. With a clear, robust style, the authors approach genetics at its most fundamental molecular level, building on students' previous exposure from other courses. Once the molecular concepts are in place, transmission genetics is more easily understood. The result is a textbook that reflects the way geneticists think about solving genetics problems in a completely integrative manner. Students relate to the organization and are able to grasp the larger concepts and their applications.

Table of Contents

Introduction Genetics in Human Society
The Universality of Genetic Principles
Model Organisms
Organizing the Study of Genetics
The Concept of the Gene
Genetic Analysis
Molecular Foundations of Genetics
DNA Structure and Replication The Genetic Material
Nucleic Acid Structure
Semiconservative DNA Replication
The Process of DNA Replication
Replication of Entire DNA Molecules
Transcription and RNA Processing The Central Dogma
Overview of Transcription and RNA Processing in Prokaryotes and Eukaryotes
Initiation of Transcription
Elongation
Termination
Transcription of rRNAs and tRNAs
mRNA Processing
Processing of rRNAs and tRNAs
Translation and Protein Function Amino Acids and Polypeptides
The Genetic Code
Ribosomes, the Sites of Translation
The Role of tRNA
Deciphering the Genetic Code
Initiation of Translation
Elongation
Termination
Protein Structure and Function
Mutation Types of Mutations
Spontaneous Mutation
Induced Mutations
DNA Repair Mechanisms
An Integrated View of Gene Expression The Anatomy of a Gene and Its Expression
The Human ?-Globin Gene
Enzymes, Biochemical Pathways, and Mutation
Genetics of Cells
Bacterial Genetics Bacterial Culture
Structure of Bacterial Chromosomes
DNA Transfer and Recombination
Transformation
Conjugation
Phage Life Cycles
Transduction
Genome Sequencing
Regulation of Gene Expression The lac Operon
Mutations in the lac Operon
The trp Operon
Regulation of Lysis and Lysogeny
Transcriptional Gene Regulation in the Eukaryotes
Gene Regulation Beyond Transcription
Recombinant DNA and Molecular Analysis Recombinant DNA
Plasmid Cloning Vectors
Vectors for Cloning Large DNA Inserts
Cloning Strategies
Expression Vectors
The Polymerase Chain Reaction (PCR)
Gel Electrophoresis
DNA, RNA and Protein Blotting
DNA Sequencing
Eukaryotic Genome Organization Repetitive and Nonrepetitive DNA
Eukaryotic DNA Packaging
The Eukaryotic Chromosome
Gene Organization in Chromosomes
Whole Genome Organization
Mitosis, Meiosis, and Life Cycles The Cell Cycle and Mitosis
Meiosis
A Closer Look at Prophase I
Life Cycles
Genetics and Organisms
Mendelian Genetics Mendel''s Experiments
The Molecular Basis of Dominance
The Cellular Basis for Segregation
The Cellular Basis of Independent Assortment
Mendelian Inheritance in Humans
Mendelian Genetics and Probability
About Mendel
Variations on Mendel''s Theme Multiple Alleles and Dominance Relations
Epistasis
Penetrance and Expressivity
DNA Markers in Genetic Analysis
Sex Determination and Sex-Related Inheritance Promotion of Cross-Fertilization
Sex Determination
Heteromorphic Chromosomes and Sex Determination
Sex-Linked Inheritance
Dosage Compensation
Sex-Influenced and Sex-Limited Traits
Chromosome Mapping The Discovery of Linkage and Crossing-Over
Two-Factor Linkage Analysis
Map Distance Correction
Three-Factor Linkage Analysis
Multifactor Chromosome Mapping
Genetic Mapping in Humans
Physical Chromosome Mapping
Practical Applications of Chromosome Mapping
Genetic Fine Structure Tetrad Analysis
Unordered Tetrad Analysis
Gene Conversion and the Mechanism of Crossing-Over
Intragenic Recombination
Complementation
Fine-Structure Mapping
Mitotic Crossing-Over
Alterations in Chromosome Number and Structure Aneuploidy
Polyploidy
Alterations of Chromosome Structure
Chromosome Alterations in Humans
Extranuclear Inheritance The Origins and Cellular Functions of Mitochondria and Plastids
Organellar Genomes
Mitochondrial Inheritance
Mitochondrial DNA and Genetic Disorders in Humans
Plastid Inheritance
Other Types of Extranuclear Inheritance
Correctly Recognizing Extranuclear Inheritance
Genetics of Populations
Population Genetics Hardy-Weinberg Equilibrium
Genetic Change in Populations
Mutation
Migration
Non-Random Mating
Selection
Random Genetic Drift
Quantitative Genetics Statistical Descriptions of Metric Characters
Additive Gene Action and Continuous Variation
Heterosis and Inbreeding
Depression
Environmental Variation
Broad-Sense Heritability
Narrow-Sense Heritability and Selection
Limits on Selection
Evolutionary Genetics Speciation
Molecular Evolution
Maintenance of Genetic Diversity
Phylogenetic Analysis
Gene Expression and the Organism
Transposable Elements Eukaryotic Transposons
Retrotransposons and Retroposons
Prokaryotic Transposons
Using Transposable Elements in Research
Developmental Genetics Differentiation and Totipotency
Genetic Control of Development in Caenorhabditis elegans
Genetic Control of Development in Drosophila melanogaster
Comparison of Mammalian and Drosophila Development Genetics
Plant Developmental Genetics
Comparison of Plant and Animal Developmental Genetics
Genes and Cancer Genetic Control of the Cell Cycle
The Molecular Basis of Cancer
Examples of Genes That Influence Cancer
The Etiology of Cancer
Cancer Prevention, Detection, and Treatment
Genes and Immunity Immune Responses
Antibody Structure
Antibody Genes
Cell-Mediated Immunity Genes
Immune System Malfunction
Antibodies as Tools in Genetic Research
Applications of Genetics
Genetics in Medicine and Forensics The Human Genome Initiative
Genetic Testing
DNA Fingerprinting
Genetic Pharmacology
Human Gene Therapy
Clinical Genetics
Genetics in Agriculture and Industry Genetic Diversity
Plant Breeding
Plant Biotechnology
Animal Breeding and Biotechnology
Applications of Genetics in Industry
Legal and Ethical Issues in Genetics Eugenics
Genetic Testing and Screening
Legal Protection and Intellectual Property Rights in Genetics
Recombinant DNA and Safety
Genetics and Science Education
Solutions To Selected Problems
Glossary
Index
Table of Contents provided by Publisher. All Rights Reserved.

Supplemental Materials

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The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.

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