Surgical Treatment of Colorectal Liver Metastases

by Capussotti, Lorenzo; Ferrero, Alessandro (COL); Muratore, Andrea (COL); Ribero, Dario (COL); Vigano, Luca (COL)

• ISBN13: 9788847018082
• ISBN10: 8847018080
• Edition: 1st
• Format: Hardcover
• Copyright: 2010-12-20
• Publisher: Springer Verlag

Summary

Surgery is the gold standard treatment of colorectal liver metastases. Patients management had a dramatic evolution during the past years: more accurate diagnostic tools and more effective chemotherapy regimens have been introduced and surgical indications have been widely broadened. A multidisciplinary treatment is now mandatory, involving oncologists, radiologists an gastroenterologists. However, many topics are still debated. In the present book all aspects of surgical treatment of colorectal liver metastases are analyzed based on a systematic, updated analysis of the literature. Aim of this book is to provide surgeons, oncologists and radiologists a clear overview of the state-of-the-art of treatment of colorectal liver metastases

Table of Contents

Epidemiology and Natural History	p. 1
Introduction	p. 1
Epidemiology	p. 2
Natural History and Disease Therapy	p. 4
References	p. 6
Diagnosis and Staging	p. 7
Introduction	p. 7
Ultrasonography	p. 8
Computed Tomography	p. 10
Magnetic Resonance Imaging	p. 13
Performance and Comparison of Imaging Modalities	p. 16
Positron Emission Tomography	p. 19
Diagnosis and Staging of Liver Metastases from Colorectal Cancer	p. 22
Liver Metastases Detection After Chemotherapy	p. 23
References	p. 24
Evolution of Resectability Criteria	p. 27
Introduction	p. 27
Resectability Criteria	p. 28
Resection Margin	p. 31
References	p. 32
Surgical Strategy	p. 35
Introduction	p. 35
Intraoperative Ultrasonography	p. 36
Parenchyma-sparing Surgery	p. 43
Laparoscopic Liver Resection	p. 45
Hepatic Pedicle Clamping	p. 48
References	p. 50
Results of Surgery and Prognostic Factors	p. 55
Introduction	p. 55
Short-term Results	p. 56
Long-term Results	p. 58
Prognostic Factors	p. 61
References	p. 71
Preoperative Chemotherapy	p. 75
Introduction	p. 75
Unresectable Liver Metastases	p. 76
Resectable Liver Metastases	p. 85
Chemotherapy-related Liver Injuries	p. 89
Disappeared Liver Metastases	p. 94
References	p. 96
Synchronous Colorectal Liver Metastases	p. 101
Introduction	p. 101
Resectable Synchronous Liver Metastases	p. 102
Unresectable Synchronous Liver Metastases	p. 110
Conclusions	p. 115
References	p. 116
Therapeutic Strategies in Unresectable Colorectal Liver Metastases	p. 121
Introduction	p. 121
Portal Vein Occlusion	p. 122
Two-stage Hepatectomy	p. 126
Interstitial Treatments	p. 130
References	p. 135
Extrahepatic Disease	p. 139
Introduction	p. 139
Lymph-node Metastases	p. 140
Peritoneal Carcinomatosis	p. 143
Pulmonary Metastases	p. 145
Other Sites	p. 147
Conclusions	p. 148
References	p. 149
Adjuvant Chemotherapy and Follow-Up	p. 153
Introduction	p. 153
Adjuvant Chemotherapy	p. 154
Follow-Up	p. 155
References	p. 156
Re-resection: Indications and Results	p. 159
Introduction	p. 159
Short-term Outcome	p. 160
Long-term Outcome	p. 161
References	p. 162
LiverMetSurvey Registry: the Italian Experience	p. 165
Introduction	p. 165
The Italian Experience	p. 167
Conclusions	p. 182
Subject Index	p. 183
Table of Contents provided by Ingram. All Rights Reserved.