Synchrotron Radiation in the Biosciences

by Chance, B.; Diesenhofer, J.; Ebashi, S.; Goodhead, D. T.; Helliwell, J. R.; Huxley, H. E.; Iizuka, T.; Kirz, J.; Mitsui, T.

• ISBN13: 9780198539865
• ISBN10: 019853986X
• Format: Hardcover
• Copyright: 1994-05-12
• Publisher: Oxford University Press

Summary

This book represents the edited proceedings of the 4th International Conference on Biophysics and Synchrotron Radiation, held in Tsukuba, Japan in 1992. It discusses advances in the application of synchrotron radiation to biophysics and medicine. The papers have been selected by adistinguished international board after refereeing, and edited for publication. It discusses advances in the application of synchrotron radiation to biophysics and medicine, of interest to researchers from many diverse fields.Just a few of the topics covered are filamentous viruses, angiography, and solution X-ray scattering.

Table of Contents

List of contributors

Crystallographic studies on macromolecular structure

Recent developments in studies of macromolecular structure by X-raycrystallography

Time-resolved macromolecular crystallography

Protein crystallography in Japan

Experience in the measurement and analysis of multiwavelength anomalousdispersion data from macromolecular crystals

Electrostatic interactions and conformational variability in cubic insulincrystals

Crystal structural analysis of tobacco necrosis virus (TNV)

Cryocrystallography of native and derivatized ribosomal crystals

Structure and function of glutathione synthetase from Escherichia coli B

Protein structure analyses exploiting the data collection efficiency andprecision provided by the macromolecule-oriented Weissenberg camera installed at Beamline 6A2 of the Photon Factory, Tsukuba

Structure and function of carbonic anhydrase: synchrotron X-raydiffraction studies of human carbonic anhydrase I and inhibitor complexes

Structure study of hydrogenase and related proteions in sulfate-reducingbacteria

''Pivot hypothesis'': a signalling mechanism in a bacterial chemotaxisreceptor

Fast Weissenberg data collection as an altrnative to the Laue method inkinetic crystallography

More information and time-dependent studies from solution X-rayscattering

Solution scattering

Time-resolved X-ray scattering study of the allosteric transition of Escherichia coli aspartate transcarbamylase

The effect of point mutations on the conformational changes of theallosteric enzyme aspartate transcarbamylase from Escherichia coli

Dynamics of microtubules from stochastic switching to periodic swinging

Synchrotron radiation X-ray diffraction and cryo electron microscopystudies of vinblastine-induced polymers of purified tubulin: evaluation of theeffects of magnesium concentration and temperature

Expression of function of calmodulin: interaction between calmodulinfragment and mastoparan

Use of X-ray solution scattering for a protein folding study

High-resolution small-angle synchrotron X-ray diffraction study onmultilamellar phospholipid systems

Temperature-jump relaxation studies on phospholipids: structuralintermediates and memory effect in phase transitions

Biology with neutron radiation

Neutrons in biology - complementarity with X-rays

Hydrogen bonding and solvent in proteins

Neutron and X-ray scattering studies of the interactions between Ca2+-binding proteins and their regulatory targets: comparisons of troponin Cand calmodulin

Characteristic structure of phosphatidylinositol diphosphate (PIP2) complexwith bovine serum albumin and water in PIP2 bilayers

Recent developments in biological X-ray absorption fine-structurespectroscopy

Sensitive and rapid biological X-ray absorption fine-structure spectroscopy

X-ray absorption spectroscopy using high-brilliance photon sources

X-ray studies of some metalloproteins

A structural model for the photosynthetic oxygen-evolving manganese complex

X-ray absorption fine structure spectroscopy and electron paramagneticresonance studies on the molecular structure and electronic state of the Mncluster in photosynthetic water-splitting enzyme

Time-resolved structure of geminate states of myoglobin CO by X-rayabsorption near-edge structure spectroscopy

The structure-function relationship of the active sites in haemoproteincatalysis

Soft X-ray absorption and X-ray magnetic dichroism in biology

X-ray beamlines and detectors

Synchrotron radiation sciences in Japan

Diffraction and diffuse scattering beamlines for biophysical applicationsat the ESRF

Developments in gas detectors for biophysics at the Daresbury SRS

X-ray television detectors

The development of X-ray television detectors at the Photon Factory

Structural studies on muscle protein, muscle contraction, andfilamentous virus

What X-rays t

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