Synopsis and Atlas of Lever's Histopathology of the Skin

by Elder, David E.; Elenitsas, Rosalie; Ioffreda, Michael; Johnson, Bernett L.; Miller, Jeffrey J.; Miller, O. Fred

• ISBN13: 9780397584208
• ISBN10: 0397584202
• Format: Hardcover
• Copyright: 1999-02-18
• Publisher: LWW

Summary

This brilliantly presented atlas is designed to complement Lever's Histopathology of the Skin, Eighth Edition. Abundantly illustrated in vivid full color, the atlas allows practitioners to recognize a diagnosis that can lead to a more detailed exploration of the topic. Based on morphology rather than pathogenesis, each disease is typically illustrated with 5 color photomicrographs and is depicted within the framework of an algorithmic classification based on location, pattern, and cell type. Culled from an enormous volume of cases, this important collection of images represents material from the last several decades up to newly collected slides, including many from cases of a more obscure nature and normally unavailable. Most images have been photographed on a Zeiss Axiophot Photomicroscope -- allowing images that represent the state-of-the-art in optics. Clinical photographs are liberally included, offering informative and enlightening material for non-dermatologist pathologists. A CD-ROM containing Lever's Histopathology of the Skin, Eighth Edition and Synopsis and Atlas of Lever's Histopathology of the Skin is available. See Media Products Section for details. Either book can be purchased together with the CD-ROM at a special low price.

Author Biography

David Elder, M.B., Ch.B., F.R.C.P.A. Professor and Associate Director Division of Anatomic Pathology Department of Pathology and Laboratory Medicine University of Pennsylvania School of Medicine Michael Ioffreda, M.D. Assistant Professor Department of Dermatology Hospital of the University of Pennsylvania Jeffrey J. Miller, M.D. Assistant Professor Department of Dermatology The Milton S. Hershey Medical Center Rosalie Elenitsas, M.D. Assistant Professor Department of Dermatology University of Pennsylvania School of Medicine Associate Director of Dermatopathology Department of Dermatology Hospital of the University of Pennsylvania Bernett Johnson, Jr., M.D. Professor Departments of Dermatology and Pathology University of Pennsylvania School of Medicine Vice-Chairman Department of Dermatology Hospital of the University of Pennsylvania O. Fred Miller III, M.D. Director Division of Dermatology Department of Medicine Geisinger Medical Center

Table of Contents

Preface	p. xix
Acknowledgments	p. xxi
Introduction	p. xxiii
Disorders Mostly Limited to the Epidermis and Stratum Corneum	p. 1
Hyperkeratosis with Hypogranulosis	p. 1
No Inflammation	p. 1
Ichthyosis Vulgaris	p. 1
Hyperkeratosis with Normal or Hypergranulosis	p. 2
No Inflammation	p. 2
X-linked Ichthyosis	p. 2
Epidermolytic Hyperkeratosis	p. 2
Scant Inflammation	p. 5
Lichen Amyloidosis and Macular Amyloidosis	p. 5
Hyperkeratosis with Parakeratosis	p. 6
Scant or No Inflammation	p. 7
Dermatophytosis	p. 7
Localized or Diffuse Hyperpigmentations	p. 9
No Inflammation	p. 9
Mucosal Melanotic Macules	p. 9
Ephelids (Freckles)	p. 9
Scant Inflammation	p. 11
Pityriasis (Tinea) Versicolor	p. 11
Localized or Diffuse Hypopigmentations	p. 13
With or Without Slight Inflammation	p. 13
Vitiligo	p. 13
References	p. 13
Localized Superficial Epidermal or Melanocytic Proliferations	p. 15
Localized Irregular Thickening of the Epidermis	p. 16
Localized Epidermal Proliferations	p. 16
Actinic Keratosis	p. 16
Eccrine Poroma	p. 16
Squamous Cell Carcinoma In Situ (Bowen's Disease)	p. 19
Bowenoid Papulosis	p. 21
Clear-Cell Squamous Cell Carcinoma In Situ	p. 21
Clear-Cell Acanthoma	p. 21
Superficial Melanocytic Proliferations	p. 22
Superficial Melanocytic Nevi and Melanomas	p. 22
Pigmented Spindle Cell Nevus	p. 23
Acral Lentiginous Melanoma	p. 23
Localized Lesions with Thinning of the Epidermis	p. 26
With Melanocytic Proliferation	p. 26
Lentigo Maligna Melanoma, In Situ or Microinvasive	p. 26
Without Melanocytic Proliferation	p. 28
Atrophic Actinic Keratosis	p. 28
Porokeratosis	p. 28
Localized Lesions with Elongated Rete Ridges	p. 30
With Melanocytic Proliferation	p. 30
Actinic Lentigo	p. 30
Lentigo Simplex	p. 31
Lentiginous Junctional Nevus	p. 31
Nevus Spilus	p. 33
Junctional or Superficial Compound Dysplastic Nevi	p. 33
Without Melanocytic Proliferation	p. 36
Epidermal Nevus	p. 36
Seborrheic Keratosis	p. 36
Acanthosis Nigricans	p. 36
Localized Lesions with Pagetoid Epithelial Proliferation	p. 39
Keratinocytic Proliferations	p. 39
Pagetoid Squamous Cell Carcinoma In Situ	p. 39
Clonal Seborrheic Keratosis	p. 39
Melanocytic Proliferations	p. 40
Melanoma In Situ or Microinvasive, Superficial Spreading Type	p. 40
Recurrent Nevus (Pseudomelanoma)	p. 42
Junctional Spitz Nevus with Pagetoid Proliferation	p. 42
Glandular Epithelial Proliferations	p. 45
Paget's Disease	p. 45
Lymphoid Proliferations	p. 46
Localized Papillomatous Epithelial Lesions	p. 46
With Viral Cytopathic Effects	p. 46
Verruca Vulgaris	p. 46
Verruca Plana	p. 46
Deep Palmoplantar Warts (Myrmecia)	p. 48
Condyloma Acuminatum	p. 49
Molluscum Contagiosum	p. 49
Parapox Virus Infections (Milker's Nodules, Orf)	p. 51
Without Viral Cytopathic Effect	p. 52
Seborrheic Keratosis	p. 53
Irregular Proliferations Extending into the Superficial Dermis	p. 55
Squamous Differentation	p. 55
Inverted Follicular Keratosis	p. 55
Basaloid Differentation	p. 56
Basal Cell Carcinoma	p. 56
Superficial Polypoid Lesions	p. 59
Melanocytic Lesions	p. 59
Polypoid Dermal and Compound Nevi	p. 59
Spindle Cell and Stromal Lesions	p. 60
Neurofibroma	p. 60
Fibroepithelial Polyp	p. 60
References	p. 62
Disorders of the Superficial Cutaneous Reactive Unit	p. 63
Superficial Perivascular Dermatitis	p. 64
Superficial Perivascular Dermatitis, Mostly Lymphocytes	p. 65
Viral Exanthem	p. 65
Tinea Versicolor	p. 66
Lupus Erythematosus, Acute	p. 66
Guttate Parapsoriasis	p. 66
Superficial Perivascular Dermatitis with Eosinophils	p. 69
Morbilliform Drug Eruption	p. 69
Allergic Urticarial Reaction (Morbilliform Drug Eruption)	p. 70
Urticaria	p. 70
Urticarial Bullous Pemphigoid	p. 71
Superficial Perivascular Dermatitis with Neutrophils	p. 73
Erysipelas	p. 73
Erysipelas/Cellulitis	p. 73
Superficial Perivascular Dermatitis with Plasma Cells	p. 73
Secondary Syphilis	p. 73
Kaposi's Sarcoma, Patch Stage	p. 73
Superficial Perivascular Dermatitis with Extravasated Red Cells	p. 75
Pityriasis Rosea	p. 75
Pityriasis Lichenoides	p. 75
Pigmented Purpuric Dermatosis	p. 75
Superficial Perivascular Dermatitis, Melanophages Prominent	p. 79
Postinflammatory Hyperpigmentation	p. 79
Superficial Perivascular Dermatitis, Mast Cells Predominant	p. 81
Urticaria Pigmentosa	p. 81
Superficial Dermatitis with Spongiosis (Spongiotic Dermatitis)	p. 82
Spongiotic Dermatitis, Lymphocytes Predominant	p. 83
Nummular Dermatitis (Eczema)	p. 83
Eczematous Dermatitis	p. 83
Spongiotic Dermatitis, with Eosinophils	p. 83
Allergic Contact Dermatitis	p. 83
Spongiotic Dermatitis, with Plasma Cells	p. 87
Spongiotic Dermatitis, with Neutrophils	p. 87
Seborrheic Dermatitis	p. 87
Superficial Dermatitis with Epidermal Atrophy (Atrophic Dermatitis)	p. 88
Atrophic Dermatitis, Scant Inflammatory Infiltrates	p. 88
Aged Skin	p. 88
Radiation Dermatitis (see also section VF1)	p. 88
Atrophic Dermatitis, Lymphocytes Predominant	p. 89
Dermatomyositis	p. 90
Atrophic Dermatitis with Papillary Dermal Sclerosis	p. 90
Lichen Sclerosus et Atrophicus	p. 90
Superficial Dermatitis with Psoriasiform Proliferation (Psoriasiform Dermatitis)	p. 93
Psoriasiform Dermatitis, Mostly Lymphocytes	p. 93
Pityriasis Rubra Pilaris	p. 93
Mycosis Fungoides, Patch/Plaque Stage	p. 93
Parapsoriasis	p. 95
Psoriasiform Dermatitis, with Plasma Cells	p. 97
Lichen Simplex Chronicus (see also section IIIE)	p. 97
Psoriasiform Dermatitis, with Eosinophils	p. 98
Chronic Allergic Dermatitis	p. 98
Psoriasiform Dermatitis, Neutrophils Prominent (Neutrophilic/Pustular Psoriasiform Dermatitis)	p. 99
Psoriasis Vulgaris	p. 99
Superficial Dermatitis with Irregular Epidermal Proliferation (Hypertrophic Dermatitis)	p. 101
Hypertrophic Dermatitis, Lymphocytes Predominant	p. 102
Prurigo Nodularis	p. 102
Irregular Epidermal Proliferation, Plasma Cells Present	p. 103
Actinic Keratosis (see also section IIA1)	p. 103
Irregular Epidermal Proliferation, Neutrophils Prominent	p. 103
Keratoacanthoma (see also section VIB1)	p. 104
Irregular Epidermal Proliferation Above a Neoplasm	p. 104
Superficial Dermatitis with Lichenoid Infiltrates (Lichenoid Dermatitis)	p. 104
Lichenoid Dermatitis, Lymphocytes Exclusively	p. 104
Lichen Planus	p. 104
Graft-Versus-Host Disease	p. 104
Mycosis Fungoides, Patch/Plaque Stage	p. 104
Lichenoid Dermatitis, Lymphocytes Predominant	p. 107
Lichen Planus-like Keratosis (Benign Lichenoid Keratosis)	p. 107
Lichenoid Dermatitis, Eosinophils Present	p. 107
Lichenoid Drug Eruptions	p. 107
Lichenoid Dermatitis, Plasma Cells Present	p. 108
Lichenoid Actinic Keratosis	p. 108
Secondary Syphilis	p. 108
Lichenoid Dermatitis, with Melanophages	p. 108
Lichenoid Dermatitis, Histiocytes Predominant	p. 111
Lichen Nitidus	p. 111
Lichenoid Dermatitis, Mast Cells Predominant	p. 113
Urticaria Pigmentosa, Lichenoid Examples (see also section IIIA2)	p. 113
Lichenoid Dermatitis with Dermal Fibroplasia	p. 113
Mycosis Fungoides, Patch Stage	p. 114
Superficial Vasculitis and Vasculopathies	p. 114
Neutrophilic Vasculitis	p. 115
Cutaneous Necrotizing (Leukocytoclastic) Vasculitis	p. 115
Gonococcemia	p. 117
Mixed Cell and Granulomatous Vasculitis	p. 117
Granuloma Faciale	p. 117
Vasculopathies with Lymphocytic Inflammation	p. 118
Pigmented Purpuric Dermatoses	p. 119
Vasculopathies with Scant Inflammation	p. 120
Stasis Dermatitis	p. 120
Thrombotic, Embolic, and Other Microangiopathies	p. 122
Lupus Anticoagulant and Antiocardiolipin Syndromes	p. 122
Superficial Dermatitis with Interface Vacuoles (Interface Dermatitis)	p. 123
Vacuolar Dermatitis, Apoptotic/Necrotic Cells Prominent	p. 123
Erythema Multiforme	p. 123
Fixed Drug Eruption	p. 126
Graft-Versus-Host Disease, Acute	p. 126
Vacuolar Dermatitis, Apoptotic Cells Usually Absent	p. 126
Dermatomyositis	p. 126
Vacuolar Dermatitis, Variable Apoptosis	p. 128
Subacute Cutaneous Lupus Erythematosus	p. 128
Vacuolar Dermatitis, Basement Membranes Thickened	p. 129
Discoid Lupus Erythematosus	p. 129
References	p. 131
Acantholytic, Vesicular, and Pustular Disorders	p. 133
Subcorneal or Intracorneal Separation	p. 134
Sub/Intracorneal Separation, Scant Inflammatory Cells	p. 134
Pemphigus Foliaceus	p. 134
Sub/Intracorneal Separation, Neutrophils Prominent	p. 134
Impetigo Contagiosa	p. 134
Folliculitis with Subcorneal Pustule Formation	p. 137
Acute Generalized Exanthematous Pustulosis	p. 137
Sub/Intracorneal Separation, Eosinophils Predominant	p. 138
Erythema Toxicum Neonatorum	p. 138
Intraspinous Keratinocyte Separation, Spongiotic	p. 138
Intraspinous Spongiosis, Scant Inflammatory Cells	p. 138
Friction Blister	p. 138
Intraspinous Spongiosis, Lymphocytes Predominant	p. 139
Dyshidrotic Dermatitis (Eczema)	p. 139
Intraspinous Spongiosis, Eosinophils Present	p. 140
Acute Contact Dermatitis (see also section IIIB1a)	p. 140
Bullous Pemphigoid, Urticarial Phase (see also section IVE3)	p. 140
Incontinentia Pigmenti	p. 140
Intraspinous Spongiosis, Neutrophils Predominant	p. 142
Dermatophytosis	p. 142
Intraspinous Keratinocyte Separation, Acantholytic	p. 142
Intraspinous Acantholysis, Scant Inflammatory Cells	p. 143
Familial Benign Pemphigus (Hailey-Hailey Disease)	p. 143
Transient Acantholytic Dermatosis (Grover's Disease)	p. 143
Intraspinous Acantholysis, Predominant Lymphocytes	p. 146
Herpes Simplex	p. 146
Varicella-Zoster Infection	p. 146
Toxic Epidermal Necrolysis and Erythema Multiforme with Intraepidermal Vesiculation	p. 146
Intraspinous Acantholysis, Eosinophils Present	p. 146
Pemphigus Vegetans	p. 146
Intraspinous Separation, Neutrophils or Mixed Cell Types	p. 151
IgA Pemphigus	p. 151
Suprabasal Keratinocyte Separation	p. 152
Suprabasal Vesicles, Scant Inflammatory Cells	p. 152
Keratosis Follicularis (Darier's Disease)	p. 152
Warty Dyskeratoma	p. 152
Suprabasal Separation, Lymphocytes and Plasma Cells	p. 154
Acantholytic Actinic Keratosis	p. 154
Suprabasal Vesicles, Lymphocytes and Eosinophils	p. 154
Pemphigus Vulgaris	p. 154
Subepidermal Vesicular Dermatitis	p. 158
Subepidermal Vesicles, Scant/No Inflammation	p. 158
Porphyria Cutanea Tarda and Other Porphyrias	p. 158
Subepidermal Vesicles, Lymphocytes Predominant	p. 161
Bullous Lichen Planus	p. 161
Polymorphous (Polymorphic) Light Eruption	p. 161
Lichen Sclerosus et Atrophicus	p. 162
Subepidermal Vesicles, Eosinophils Prominent	p. 164
Bullous Pemphigoid	p. 164
Bullous Drug Eruption	p. 165
Herpes Gestationis	p. 165
Subepidermal Vesicles, Neutrophils Prominent	p. 165
Dermatitis Herpetiformis	p. 165
Linear IgA Dermatosis	p. 165
Bullous Lupus Erythematosus	p. 168
Subepidermal Vesicles, Mast Cells Prominent	p. 170
Bullous Mastocytosis	p. 170
References	p. 171
Perivascular, Diffuse, and Granulomatous Infiltrates of the Reticular Dermis	p. 173
Superficial and Deep Perivascular Infiltrates without Vascular Damage or Vasculitis	p. 175
Perivascular Infiltrates, Lymphocytes Predominant	p. 175
Erythema Annulare Centrifugum	p. 175
Erythema Chronicum Migrans (see also section VA5)	p. 175
Tumid Lupus Erythematosus	p. 175
Perivascular Infiltrates, Neutrophils Predominant	p. 177
Cellulitis	p. 177
Perivascular Infiltrates, Lymphocytes and Eosinophils	p. 178
Papular Urticaria	p. 178
Pruritic Urticarial Papules and Plaques of Pregnancy	p. 178
Perivascular Infiltrates, with Plasma Cells	p. 179
Secondary Syphilis	p. 179
Tertiary Syphilis	p. 181
Morphea (see also section VF)	p. 181
Perivascular Infiltrates, Mixed Cell Types	p. 184
Erythema Chronicum Migrans	p. 184
Vasculitis and Vasculopathies	p. 185
Vascular Damage, Scant Inflammatory Cells	p. 185
Degos' Syndrome	p. 185
Vasculitis, Lymphocytes Predominant	p. 186
Pernio	p. 187
Pityriasis Lichenoides et Varioliformis Acuta	p. 189
Cytomegalovirus Infection	p. 189
Erythema Chronicum Migrans	p. 189
Vasculitis, Neutrophils Prominent	p. 189
Polyarteritis Nodosa and Microscopic Polyangiitis	p. 189
Leukocytoclastic Vasculitis	p. 191
Erythema Elevatum Diutinum	p. 191
Vasculitis, Mixed Cell Types and/or Granulomas	p. 193
Churg--Strauss Syndrome (Allergic Granulomatosis)	p. 193
Papulonecrotic Tuberculid	p. 193
Thrombotic and Other Microangiopathies	p. 193
Calciphylaxis	p. 193
Livedo Reticularis	p. 193
Diffuse Infiltrates of the Reticular Dermis	p. 195
Diffuse Infiltrates, Lymphocytes Predominant	p. 195
Jessner's Lymphocytic Infiltration of the Skin	p. 195
Leukemia Cutis	p. 195
Diffuse Infiltrates, Neutrophils Predominant	p. 198
Acute Febrile Neutrophilic Dermatosis (Sweet's Syndrome)	p. 198
Erysipelas/Cellulitis	p. 198
Diffuse Infiltrates, "Histiocytoid" Cells Predominant	p. 200
Lepromatous Leprosy	p. 200
Langerhans Cell Histiocytosis (Histiocytosis X)	p. 200
Xanthelasma	p. 202
Diffuse Infiltrates, Plasma Cells Prominent	p. 203
Secondary Syphilis	p. 203
Diffuse Infiltrates, Mast Cells Predominant	p. 204
Diffuse Infiltrates, Eosinophils Predominant	p. 204
Eosinophilic Cellulitis (Wells' Syndrome)	p. 204
Tick Bite	p. 204
Diffuse Infiltrates, Mixed Cell Types	p. 204
Cutaneous Leishmaniasis	p. 204
Diffuse Infiltrates, Pigment Cells	p. 208
Nevi of Ota and Ito and Dermal Melanocyte Hamartoma	p. 208
Diffuse Infiltrates, Extensive Necrosis	p. 210
Gangrenous Ischemic Necrosis	p. 210
Diffuse or Nodular Infiltrates of the Reticular Dermis with Epidermal Proliferation	p. 211
Epidermal Proliferation with Mixed Cellular Infiltrates	p. 211
North American Blastomycosis	p. 211
Deep Fungal Infections (General)	p. 211
Nodular Inflammatory Infiltrates of the Reticular Dermis: Granulomas, Abscesses, and Ulcers	p. 213
Epithelioid Cell Granulomas without Necrosis	p. 213
Sarcoidosis	p. 213
Lupus Vulgaris	p. 215
Epithelioid Cell Granulomas with Necrosis	p. 215
Tuberculosis	p. 215
Tuberculoid Leprosy	p. 216
Lupus Miliaris Disseminatus Facei (Granulomatous Rosacea)	p. 216
Palisading Granulomas	p. 218
Granuloma Annulare	p. 218
Necrobiosis Lipoidica Diabeticorum	p. 220
Necrobiotic Xanthogranuloma with Paraproteinemia	p. 220
Rheumatoid Nodules	p. 220
Mixed Cell Granulomas	p. 223
Foreign Body Reactions	p. 223
Inflammatory Nodules with Prominent Eosinophils	p. 224
Angiolymphoid Hyperplasia with Eosinophilia and Kimura's Disease	p. 224
Scabetic Nodule	p. 226
Inflammatory Nodules with Mixed Cell Types	p. 226
Sporotrichosis	p. 226
Inflammatory Nodules with Necrosis and Neutrophils (Abscesses)	p. 228
Botryomycosis	p. 228
Chromoblastomycosis	p. 230
Inflammatory Nodules with Prominent Necrosis	p. 230
Aspergillosis	p. 230
Chronic Ulcers and Sinuses Involving the Reticular Dermis	p. 232
Chancroid	p. 232
Pyoderma Gangrenosum	p. 233
Chondrodermatitis Nodularis Helicis	p. 234
Dermal Matrix Fiber Disorders	p. 235
Fiber Disorders, Collagen Increased	p. 235
Scleroderma	p. 235
Radiation Dermatitis	p. 237
Fiber Disorders, Collagen Reduced	p. 239
Focal Dermal Hypoplasia Syndrome (Goltz)	p. 239
Fiber Disorders, Elastin Increased or Prominent	p. 241
Pseudoxanthoma Elasticum	p. 241
Fiber Disorders, Elastin Reduced	p. 242
Macular Atrophy (Anetoderma)	p. 242
Fiber Disorders, Perforating	p. 242
Elastosis Perforans Serpiginosum	p. 243
Reactive Perforating Collagenosis	p. 243
Perforating Folliculitis	p. 243
Deposition of Material in the Dermis	p. 244
Increased Normal Nonfibrous Matrix Constituents	p. 244
Digital Mucous Cysts and Focal Mucinosis	p. 245
Mucinosis in Lupus Erythematosus	p. 245
Myxedema	p. 245
Scleredema	p. 245
Scleromyxedema	p. 245
Increased Material Not Normally Present in the Dermis	p. 247
Gout	p. 247
Colloid Milium	p. 248
Idiopathic Calcinosis Cutis	p. 248
Cryoglobulinemia	p. 250
Keratin Granuloma	p. 250
Suture Granuloma	p. 250
Parasitic Infestations of the Skin	p. 252
Larva Migrans Eruption	p. 252
References	p. 253
Tumors and Cysts of the Dermis and Subcutis	p. 255
Small Cell Tumors	p. 257
Tumors of Lymphocytes or Hemopoietic Cells	p. 257
Cutaneous B-Cell Lymphoma	p. 257
Cutaneous Diffuse B-Cell Lymphoma	p. 259
Cutaneous T-Cell Lymphoma, Tumor Stage	p. 259
Tumors of Lymphocytes and Mixed Cell Types	p. 259
B-Cell Cutaneous Lymphoid Hyperplasia (Pseudolymphoma, Lymphocytoma Cutis)	p. 259
Tumors of Plasma Cells	p. 261
Cutaneous Plasmacytoma and Multiple Myeloma	p. 261
Small Round Cell Tumors	p. 262
Cutaneous Small Cell Undifferentiated Carcinoma (Merkel Cell Tumor)	p. 262
Metastatic Small Cell Carcinoma	p. 263
Large Polygonal and Round Cell Tumors	p. 264
Squamous Cell Tumors	p. 264
Squamous Cell Carcinoma, Deep	p. 265
Keratoacanthoma	p. 267
Inverted Follicular Keratosis	p. 268
Pseudoepitheliomatous Hyperplasia	p. 268
Proliferating Trichilemmal Cyst (Pilar Tumor)	p. 268
Prurigo Nodularis	p. 268
Adenocarcinomas	p. 271
Metastatic Adenocarcinoma	p. 271
Metastatic Pulmonary Adenocarcinoma	p. 271
Metastatic Mammary Carcinoma	p. 271
Melanocytic Tumors	p. 271
Melanocytic Nevi, Acquired and Congenital Types	p. 271
Acquired Nevi	p. 274
Congenital Nevus	p. 274
Acral Nevus	p. 274
Balloon Cell Nevus	p. 274
Halo Nevus	p. 274
Regressing Melanoma	p. 278
Blue Nevus	p. 278
Cellular Blue Nevus	p. 278
Deep Penetrating Nevus	p. 279
Spitz Nevus	p. 279
Nodular Melanoma	p. 280
Metastatic Malignant Melanoma	p. 284
Metastatic Malignant Melanoma, Satellite Lesion	p. 284
Epidermotropic Metastatic Melanoma	p. 284
Eccrine Tumors	p. 288
Eccrine Spiradenoma	p. 288
Cylindroma	p. 289
Poroma	p. 289
Syringoma	p. 289
Nodular Hidradenoma	p. 289
Clear Cell Syringoma	p. 289
Chondroid Syringoma	p. 289
Microcystic Adnexal Carcinoma	p. 289
Mucinous Eccrine Carcinoma	p. 296
Apocrine Tumors	p. 296
Tubular Apocrine Adenoma	p. 296
Syringocystadenoma Papilliferum	p. 297
Pilar Tumors	p. 298
Trichoepithelioma	p. 298
Dilated Pore of Winer	p. 298
Pilar Sheath Acanthoma	p. 298
Trichilemmoma	p. 298
Trichofolliculoma	p. 302
Fibrofolliculoma	p. 302
Trichoadenoma	p. 302
Pilomatricoma	p. 302
Sebaceous Tumors	p. 304
Sebaceous Adenoma and Sebaceous Epithelioma (Sebaceoma)	p. 304
Sebaceous Hyperplasia	p. 306
Nevus Sebaceus of Jadassohn	p. 306
Sebaceous Epithelioma	p. 306
Sebaceous Carcinoma	p. 306
"Histiocytoid" Tumors	p. 308
Xanthomas and Xanthelasma	p. 308
Eruptive Xanthoma	p. 309
Verruciform Xanthoma	p. 309
Juvenile Xanthogranuloma	p. 309
Reticulohistiocytosis	p. 312
Tumors of Large Lymphoid Cells	p. 313
Cutaneous CD30+ (Ki-1+) Anaplastic Large Cell Lymphoma	p. 313
Lymphomatoid Papulosis	p. 314
Leukemia Cutis	p. 314
Mast Cell Tumors	p. 317
Urticaria Pigmentosa, Nodular Lesions	p. 317
Tumors with Prominent Necrosis	p. 319
Epithelioid Sarcoma	p. 319
Miscellaneous and Undifferentiated Epithelial Tumors	p. 321
Granular Cell Tumor	p. 321
Cellular Neurothekeoma	p. 321
Metastatic Malignant Melanoma	p. 321
Spindle Cell, Pleomorphic and Connective Tissue Tumors	p. 321
Fibrohistiocytic Spindle Cell Tumors	p. 321
Dermatofibroma	p. 321
Cellular Dermatofibroma	p. 323
Dermatofibrosarcoma Protuberans	p. 323
Atypical Fibroxanthoma	p. 325
Malignant Fibrous Histiocytoma	p. 326
Fibrous Papule (Angiofibroma)	p. 326
Recurrent Infantile Digital Fibromatosis	p. 332
Keloid	p. 332
Acquired Digital Fibrokeratoma	p. 332
Giant Cell Tumor of Tendon Sheath	p. 332
Nodular Fasciitis	p. 332
Mucocele	p. 332
Digital Mucous Cyst	p. 332
Cutaneous Myxoma	p. 332
Schwannian/Neural Spindle Cell Tumors	p. 333
Neurofibromas	p. 333
Neurofibromatosis	p. 335
Schwannoma (Neurilemmoma)	p. 335
Palisaded Encapsulated Neuroma	p. 335
Accessory Digit	p. 335
Spindle Cell Tumors of Muscle	p. 336
Leiomyomas	p. 336
Angioleiomyoma	p. 338
Smooth Muscle Hamartoma	p. 338
Leiomyosarcoma	p. 338
Melanocytic Spindle Cell Tumors	p. 340
Desmoplastic Melanoma	p. 340
Tumors and Proliferations of Angiogenic Cells	p. 342
Pyogenic Granuloma (Lobular Capillary Hemangioma)	p. 342
Intravascular Papillary Endothelial Hyperplasia (Masson's Hemangio-Endotheliome Vegetant Intravasculaire)	p. 343
Stasis Dermatitis with Vascular Proliferation (Acroangiodermatitis, Pseudo-Kaposi's Sarcoma)	p. 343
Kaposi's Sarcoma	p. 344
Cutaneous Angiosarcoma	p. 346
Angiokeratoma	p. 346
Arteriovenous Hemangioma	p. 346
Cavernous Hemangioma	p. 346
Cherry Hemangioma	p. 346
Microvenular Hemangioma	p. 346
Cutaneous Lymphangioma	p. 346
Venous Lake	p. 348
Epithelioid Hemangioendothelioma	p. 348
Glomangioma	p. 348
Subungual Glomus Tumor	p. 348
Tumors of Adipose Tissue	p. 353
Nevus Lipomatosus Superficialis	p. 353
Lipoma	p. 354
Angiolipomas	p. 354
Spindle Cell Lipoma	p. 354
Pleomorphic Lipomas	p. 357
Liposarcoma	p. 357
Tumors of Cartilaginous Tissue	p. 357
Tumors of Osseous Tissue	p. 357
Albright's Hereditary Osteodystrophy and Osteoma Cutis	p. 357
Cysts of the Dermis and Subcutis	p. 358
Pilar Differentiation	p. 358
Epidermal or Infundibular Cyst	p. 358
Trichilemmal (Pilar) Cyst	p. 359
Steatocystoma	p. 359
Vellus Hair Cyst	p. 359
Eccrine and Similar Differentiation	p. 361
Eccrine Hidrocystoma	p. 361
Median Raphe Cyst	p. 361
Bronchogenic Cyst	p. 361
Cutaneous Endometriosis	p. 361
Apocrine Differentiation	p. 364
Apocrine Hidrocystoma	p. 364
Hidradenoma Papilliferum	p. 364
References	p. 366
Inflammatory and Other Benign Disorders of Skin Appendages	p. 367
Pathology Involving Hair Follicles	p. 368
Scant Inflammation	p. 368
Androgenetic Alopecia	p. 368
Trichotillomania	p. 368
Telogen Effluvium	p. 370
Keratosis Pilaris	p. 372
Lymphocytes Predominant	p. 372
Alopecia Areata	p. 372
Lichen Planopilaris	p. 372
Discoid Lupus Erythematosus of the Scalp	p. 378
Alopecia Mucinosa	p. 378
Rosacea	p. 378
Eosinophils Prominent	p. 378
Eosinophilic Pustular Folliculitis	p. 378
Neutrophils Prominent	p. 380
Acute Deep Folliculitis (Furuncle)	p. 380
Tinea Capitis	p. 380
Majocchi's Granuloma	p. 380
Herpes Simplex Viral Folliculitis	p. 381
Plasma Cells Prominent	p. 383
Folliculitis (Acne) Keloidalis Nuchae	p. 383
Tinea Capitis	p. 383
Fibrosing and Suppurative Follicular Disorders	p. 383
Follicular Occlusion Triad (Hidradenitis Suppurativa, Acne Conglobata, and Perifolliculitis Capitis Abscedens et Suffodiens)	p. 383
Folliculitis Decalvans	p. 385
Pathology Involving Sweat Glands	p. 389
Scant Inflammation	p. 389
Eccrine Nevus	p. 389
Lymphocytes Predominant	p. 389
Lichen Striatus	p. 389
With Plasma Cells	p. 391
Lupus Erythematosus	p. 391
With Eosinophils	p. 391
Arthropod Bite	p. 391
With Neutrophils	p. 391
Neutrophilic Eccrine Hidradenitis	p. 391
Pathology Involving Nerves	p. 393
Lymphocytic Infiltrates	p. 393
Mixed Inflammatory Infiltrates	p. 393
Nerve Involvement in Leprosy	p. 393
Erythema Chronica Migrans with Nerve Involvement	p. 394
Arthropod Bite Reaction with Nerve Involvement	p. 394
Neoplastic Infiltrates	p. 394
Neurotropic Melanoma	p. 395
Pathology of the Nails	p. 395
Lymphocytic Infiltrates	p. 395
Acral Lentiginous Melanoma	p. 395
Lymphocytes with Neutrophils	p. 396
Onychomycosis	p. 396
Vesiculobullous Diseases	p. 397
Darier's Disease	p. 398
Parasitic Infestations	p. 398
Scabies	p. 398
References	p. 398
Disorders of the Subcutis	p. 399
Subcutaneous Vasculitis and Vasculopathy (Septal or Lobular)	p. 400
Neutrophilic Vasculitis	p. 400
Subcutaneous Polyarteritis Nodosa	p. 400
Lymphocytic Vasculitis	p. 400
Granulomatous Vasculitis	p. 401
Erythema Induratum (Nodular Vasculitis)	p. 401
Septal Panniculitis Without Vasculitis	p. 401
Septal Panniculitis, Lymphocytes and Mixed Infiltrates	p. 401
Erythema Nodosum	p. 401
Septal Panniculitis, Granulomatous	p. 404
Subcutaneous Granuloma Annulare	p. 404
Septal Panniculitis, Sclerotic	p. 405
Scleroderma and Morphea	p. 405
Lobular Panniculitis Without Vasculitis	p. 406
Lobular Panniculitis, Lymphocytes Predominant	p. 406
Lupus Erythematosus Panniculitis	p. 406
Lobular Panniculitis, Lymphocytes and Plasma Cells	p. 408
Lobular Panniculitis, Neutrophilic	p. 408
Lobular Panniculitis, Eosinophils Prominent	p. 408
Lobular Panniculitis, Histicytes Prominent	p. 408
Histiocytic Cytophagic Panniculitis (Subcutaneous T-Cell Lymphoma with Hemophagocytic Syndrome)	p. 408
Lobular Panniculitis, Mixed with Foam Cells	p. 409
Relapsing Febrile Nodular Nonsuppurative Panniculitis (Weber-Christian Disease)	p. 409
Lobular Panniculitis, Granulomatous	p. 411
Subcutaneous Sarcoidosis	p. 411
Lobular Panniculitis, Crystal Deposits, Calcifications	p. 411
Subcutaneous Fat Necrosis of the Newborn	p. 411
Calcifying Panniculitis (Calciphylaxis)	p. 411
Lobular Panniculitis, Necrosis Prominent	p. 414
Subcutaneous Nodular Fat Necrosis in Pancreatic Disease	p. 414
Lobular Panniculitis, Embryonic Fat Pattern	p. 415
Localized Lipoatrophy and Lipodystrophy	p. 415
Lobular Panniculitis, Miscellaneous	p. 415
Lipomembranous Change or Lipomembranous Panniculitis	p. 415
Mixed Lobular and Septal Panniculitis	p. 417
With Hemorrhage or Sclerosis	p. 417
Panniculitis Due to Physical or Chemical Agents	p. 417
With Many Neutrophils	p. 418
Necrotizing Fasciitis	p. 418
With Many Eosinophils	p. 418
Eosinophilic Fasciitis (Shulman's Syndrome)	p. 418
With Many Lymphocytes	p. 420
Subcutaneous Panniculitic or Lipotropic T-Cell Lymphoma	p. 420
With Cytophagic Histiocytes	p. 421
Sinus Histiocytosis with Massive Lymphadenopathy (Rosai-Dorfman)	p. 421
With Granulomas	p. 422
Mycobacterial Panniculitis	p. 422
Erythema Nodosum Leprosum (Type 2 Leprosy Reaction)	p. 424
Subcutaneous Abscesses	p. 424
With Neutrophils	p. 424
Phaeohyphomycotic Cyst	p. 424
References	p. 425
Alphabetical List of Diseases	p. 427
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