Tabulation of FARAD Comparative and Veterinary Pharmacokinetic Data

by Craigmill, Arthur L.; Riviere, Jim E.; Webb, Alistair I.

• ISBN13: 9780813813493
• ISBN10: 0813813492
• Edition: 1st
• Format: Hardcover
• Copyright: 2006-01-18
• Publisher: Wiley-Blackwell

Summary

The use of therapeutic and antimicrobial agents to prevent, to control, and to eradicate disease in herd animals has without question revolutionized food animal production capacity. But how much of a good thing is too much? 20th century advances in disease diagnosis and treatment have led to 21st century concerns about the health risks posed to consumers when the animals they consume have been exposed to antimicrobials, therapeutic drugs, pesticides and other environmental contaminants. The Food Animal Residue Avoidance Databank provides the pharmacologic data that veterinarians and producers need to screen animals that have been exposed to chemicals and to ensure that dangerously contaminated tissues of food-producing animals do not enter the human food chain. Established only twenty years ago under the auspices of the USDA, FARAD is an international venture that brings together and collates information on applications of pharmacokinetic principles to drug and chemical residue avoidance--information that previously has been spread throughout the literature. Now, the Tabulation of FARAD Comparative and Veterinary Pharmacokinetic Data brings together in a single source all the most current information on chemical residues in food animals, and provides easy access and numerous tables that offer essential pharmacokinetic data for chemicals in serum, plasma, blood, or in other matrices. This updated one-of-a-kind volume also features additional data on laboratory rodents, dogs, cats, and horses to facilitate broader interspecies extrapolations. This easy-to-use and newly-updated publication is the essential reference on the subject and belongs in the library of veterinarians, toxicologists, pharmacologists, animal scientists, food hygienists, and regulatory personnel involved in human food safety.

Author Biography

Arthur L. Craigmill, PhD
Toxicology Specialist
Department of Environmental Toxicology
University of California-Davis

Jim Riviere, DVM, PhD
Burroughs Wellcome Distinguished Professor
Director, Center for Cutaneous Toxicology and Residue Pharmacology
College of Veterinary Medicine
North Carolina State University

Alistair I. Webb, BVSc, PhD
Professor and Associate Chair
Dept. of Physiological Sciences
College of Veterinary Medicine
University of Florida

Table of Contents

About the Authors	viii
Foreword	ix
Acknowledgements	xi
Introduction	1	(12)
Section 1. Antimicrobial Agents
Penicillins	13	(180)
Cephalosporins	193	(72)
Tetracyclines	265	(98)
Macrolides	363	(90)
Aminoglycosides	453	(118)
Sulfonamides	571	(148)
Fluoroquinolines	719	(140)
Miscellaneous	859	(266)
Section 2. Therapeutic Drugs
Central Nervous System	1125	(60)
Anthelmintics	1185	(78)
NSAIDs	1263	(74)
Narcotic analgesics	1337	(28)
Hormones	1365	(30)
Cardiovascular-renal	1395	(28)
Miscellaneous	1423	(88)
Antidotes	1511	(86)
Section 3. Pesticides
Organophosphate and Carbamates	1597	(28)
Organochlorine	1625	(50)
Pyrethroids	1675	(4)
Herbicides	1679	(16)
Rodenticides	1695	(8)
Fungicides	1703	(4)
Miscellaneous	1707	(6)
Section 4. Environmental Toxicants
Dioxins and Dibenzofurans	1713	(32)
Plant and Animal Toxins	1745	(24)
Metals	1769	(12)
PCBs and PBBs	1781	(8)
Hydrocarbons	1789	(4)
Miscellaneous	1793	(10)
Bibliography	1803	(88)
Generic Index	1891	(12)
Citation Index	1903