Note: Supplemental materials are not guaranteed with Rental or Used book purchases.
Purchase Benefits
What is included with this book?
Introduction | p. v |
Cancer Biology, Signaling Pathways, and Malignant Transformation | p. 1 |
Hallmarks of Cancer | p. 1 |
Application of the Hallmarks of Cancer | p. 2 |
Invasion and Metastasis | p. 18 |
Epigenetics | p. 30 |
Summary | p. 34 |
References | p. 34 |
Targeted Cancer Therapy: External and Internal Signaling Pathway Targets | p. 39 |
Monoclonal Antibodies | p. 42 |
Membrane-Bound Receptor Kinases (e.g., EGFR, HER2, HGF/c-Met, IGFR pathways) | p. 73 |
Hepatocyte Growth Factor (HGF/c-Met) Receptor Pathway Targets | p. 125 |
Insulin-like Growth Factor Receptor Pathway Targets | p. 127 |
Intracellular Signaling Kinases (e.g., src, P13k/Akt/mTOR; MAPK; sonic hedgehog pathways) | p. 128 |
Protein Kinase Signaling Pathways | p. 129 |
Protein Kinase Inhibitors | p. 136 |
Protein Dynamics: Heat Shock Proteins and Ubiquitin-Proteasome Inhibitors | p. 150 |
Epigenetic Abnormalities (DNA Methyltransferase and Histone Deacetylase) | p. 160 |
Tumor Vasculature and Microenvironment | p. 175 |
References | p. 175 |
Tumor Vasculature | p. 185 |
Targeting Angiogenesis | p. 185 |
Antiangiogenic Drug Therapy | p. 194 |
Hypoxia-Inducible Factor, mTOR, and Angiogenesis | p. 198 |
Nursing Considerations and Drug Information | p. 203 |
References | p. 250 |
Targeting the Microenvironment: Bone Metastasis, Apoptosis, DNA Repair, and Mitosis | p. 255 |
Bone Metastasis | p. 255 |
Pharmacologic Management | p. 262 |
Targeting Apoptosis | p. 271 |
DNA Repair Gene Mutations: Opportunities from Synthetic Lethality | p. 277 |
Mitotic Kinase Inhibitors | p. 280 |
Summary | p. 284 |
References | p. 284 |
Challenges in Caring for Patients Receiving Targeted Therapy | p. 289 |
Drag Interactions: Focus on the P450 Microenzyme System | p. 289 |
Encouraging Patient Adherence and Persistence | p. 302 |
References | p. 310 |
Glossary | p. 313 |
Index | p. 329 |
Table of Contents provided by Ingram. All Rights Reserved. |
The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.
The Used, Rental and eBook copies of this book are not guaranteed to include any supplemental materials. Typically, only the book itself is included. This is true even if the title states it includes any access cards, study guides, lab manuals, CDs, etc.