Textbook of Ocular Pharmacology

by Zimmerman, Thom J., M.D.; Kooner, Karanjit; Sharir, Mordechai, M.D.; Fechtner, Robert D., M.D.

• ISBN13: 9780781703062
• ISBN10: 0781703069
• Format: Hardcover
• Copyright: 1997-09-01
• Publisher: Lippincott Williams & Wilkins

Summary

Univ. of Louisville, KY. Extensive reference on the present and emerging knowledge of ocular pharmacology. For ophthalmologists and residents-in-training. 97 contributors, 92 U.S.

Table of Contents

Section Editors	xiii	(4)
Contributing Authors	xvii	(10)
Preface	xxvii	(2)
Acknowledgments	xxix
Section I: General Ocular Pharmacology	1	(216)
Overview	1	(2)
Mordechai Sharir
1. The History of Ocular Pharmacology	3	(6)
Mordechai Sharir
2. Pharmacodynamics: Drug-Receptor Interactions	9	(26)
Frederick W. Benz
3. Drug Reactions Not Mediated via Receptors	35	(6)
Anat Loewenstein
Moshe Lazar
4. Cholinergics	41	(10)
Craig E. Crosson
5. Eicosanoid Receptors in Ocular Tissues	51	(10)
Parimal Bhattacherjee
6. Steroids in Ocular Therapy	61	(14)
Prasad S. Kulkarni
7. Adrenergic Pharmacology of the Anterior Segment	75	(20)
David E. Potter
Gary D. Novack
8. Immunosuppressive Therapy for Uveitis	95	(24)
Margaret K. L. Cheung
James T. Rosenbaum
9. Ocular Pharmacokinetics	119	(20)
Ronald D. Schoenwald
10. Basic Considerations of Ocular Drug-Delivery Systems	139	(12)
Amir Bar-Ilan
Ron Neumann
11. Development of New Drugs for Ophthalmology	151	(14)
Gary D. Novack
12. Ethical Issues in Ophthalmic Research	165	(6)
Mark P. Nasisse
13. The Ophthalmologist as Clinical Investigator	171	(8)
Gary D. Novack
14. Introduction to Toxicology	179	(8)
Harrell E. Hurst
15. Effect of Disease on Drug Disposition	187	(10)
Bruce A. Mueller
Steven R. Abel
16. Effect of Age on Drug Disposition	197	(8)
William F. Buss
Steven R. Abel
Bruce A. Mueller
17. Effect of Pregnancy on Drug Disposition	205	(12)
Helen Y. How
Joseph A. Spinnato
Section II: Glaucoma	217	(144)
Overview	217	(2)
Karanjit S. Kooner
Thom J. Zimmerman
18. Definitions and Classification of Glaucoma	219	(2)
Robert D. Fechtner
Karanjit S. Kooner
19. Direct, Indirect, and Dual-Action Parasympathetic Drugs	221	(18)
Paul L. Kaufman
B'Ann True Gabelt
20. Epinephrine and Dipivefrin	239	(8)
Ervin N. Fang
Michael A. Kass
21. Alpha-2 Agonists in Glaucoma Therapy	247	(8)
Mark S. Juzych
Alan L. Robin
Gary D. Novack
22. Thymoxamine (Alpha-Adrenergic Antagonist)	255	(6)
Karanjit S. Kooner
23. Beta-blockers	261	(16)
Mark S. Juzych
Thom J. Zimmerman
24. Oral Carbonic Anhydrase Inhibitors	277	(10)
Jeffrey G. Piper
25. Topical Carbonic Anhydrase Inhibitors	287	(4)
Mordechai Sharir
26. Hyperosmotic Agents	291	(6)
Kuldev Singh
Theodore Krupin
27. Antifibrosis Agents: Pharmacologic Inhibition of Wound Healing	297	(18)
Bruce C. Henderson
George F. Nardin
28. Prostaglandins and Prostaglandin Analogues	315	(14)
Carl B. Camras
Laszlo Z. Bito
Carol B. Toris
29. Future Role of Neuroprotective Agents in Glaucoma	329	(12)
Ozlem Evrem Abbasoglu
Karanjit S. Kooner
30. Medical Trabeculocanulotomy	341	(6)
R. Rand Allingham
31. Physiologic Aspects of Glaucoma and Its Current and Future Management	347	(14)
Laszlo Z. Bito
Section III: Retina	361	(110)
Overview	361	(2)
David V. Weinberg
Lee M. Jampol
32. Antibiotics and Antifungals	363	(24)
Travis A. Meredith
33. Antivirals in the Treatment of Retinal Diseases	387	(22)
Ramana S. Moorthy
David V. Weinberg
34. Pharmacologic Therapy for Cystoid Macular Edema	409	(8)
Lee M. Jampol
35. Proliferative Vitreoretinopathy: Biology and Pharmacology	417	(12)
Glenn J. Jaffe
P. Andrew Pearson
36. Drugs Affecting the Coagulation/Fibrinolysis Pathways	429	(14)
George A. Williams
37. Ocular Pharmacology of Diabetic Retinopathy	443	(4)
Lawrence I. Rand
38. Medical Therapy for Macular Degeneration	447	(8)
Johanna M. Seddon
Joan W. Miller
39. Angiogenesis and Growth Factors	455	(16)
Joan W. Miller
Patricia A. D'Amore
Section IV: Cornea and External Diseases	471	(210)
Overview	471	(2)
George R. John
Herbert E. Kaufman
40. Penicillins and Cephalosporins	473	(20)
Adam H. Kaufman
Jules Baum
41. Antiparasitic Agents	493	(14)
Lisa D. Kelly
42. The Tetracyclines	507	(8)
Carol L. Karp
Eduardo C. Alfonso
43. Erythromycin, Clarithromycin, and Azithromycin	515	(10)
Robert E. Leonard II
Carol L. Karp
Eduardo C. Alfonso
44. Chloramphenicol	525	(6)
Carol L. Karp
Joseph R. Gussler
Eduardo C. Alfonso
45. Aminoglycosides in Ophthalmology	531	(6)
Steven M. Patalano
Robert A. Hyndiuk
46. Fluoroquinolones	537	(12)
Gregory S. H. Ogawa
Robert A. Hyndiuk
47. Peptide Antibiotics: Vancomycin, Bacitracin, and Polymyxin B	549	(10)
Gerard D'Aversa
George A. Stern
48. Rifampin	559	(6)
W. Craig Fowler
James E. Arena
Mark J. Iacobucci
49. Amebic Disease of the Eye	565	(10)
Hassan Alizadeh
Jerry Niederkorn
James P. McCulley
50. Antivirals	575	(12)
James M. Hill
Richard J. O'Callaghan
Bryan M. Gebhardt
51. Pharmacotherapy of Fungus Infections of the Eye	587	(22)
Terrence P. O'Brien
Peter Rhee
52. Antiallergic Therapies	609	(26)
Mark B. Abelson
Paula J. McGarr
Kevin P. Richard
53. Intraocular Irrigating Solutions	635	(20)
Henry F. Edelhauser
Roger Amass
Richard Lambert
54. Surgical Viscoelastic Substances	655	(6)
Gavin J. Roberts
Robert A. Hyndiuk
55. Antiseptics and Disinfectants	661	(6)
Rajesh K. Rajpal
Stephen R. Glaser
56. Mitomycin Treatment of Corneal Disease	667	(4)
Roswell R. Pfister
57. Cyanoacrylate Tissue Adhesives	671	(4)
George R. John
58. Future Developments in Corneal Therapy: Growth Factors	675	(6)
Gregory Schultz
Section V: Uveitis	681	(82)
Overview	681	(2)
C. Stephen Foster
Albert Vitale
59. Pharmacology of Medical Therapy for Uveitis	683	(20)
Albert Vitale
C. Stephen Foster
60. Mydriatic and Cycloplegic Agents	703	(10)
Albert Vitale
C. Stephen Foster
61. Nonsteroidal Antiinflammatory Drugs	713	(10)
Albert Vitale
C. Stephen Foster
62. Immunosuppressive Chemotherapy	723	(40)
Albert Vitale
C. Stephen Foster
Section VI: Anesthesia	763	(18)
Overview	763	(2)
Martin A. Acquadro
63. Anesthetic and Perianesthetic Medications	765	(6)
Martin A. Acquadro
64. Anesthetic Considerations for Ophthalmic Surgery	771	(10)
Martin A. Acquadro
Section VII: Ocular Medications for Pediatric Patients	781	(24)
Overview	781	(2)
Forrest D. Ellis
65. Topical Ophthalmic Preparations Used for Infants and Children	783	(4)
Forrest D. Ellis
66. Cycloplegic Agents	787	(4)
Forrest D. Ellis
67. Topical and Local Anesthetic Agents	791	(4)
Forrest D. Ellis
68. Antiglaucoma Medications	795	(6)
Forrest D. Ellis
69. Ocular Antiinflammatory Agents	801	(4)
Forrest D. Ellis
Section VIII: Diagnostic Drugs	805	(60)
Overview by Carol F. Zimmerman	805	(2)
70. Mydriatic and Cycloplegic Drugs	807	(20)
Carol F. Zimmerman
R. Nick Hogan
Trang Diem Le
71. Drugs for the Diagnosis of Pupillary Disorders	827	(10)
Carol F. Zimmerman
72. Drugs for the Diagnosis and Treatment of Myasthenia Gravis	837	(12)
Gil I. Wolfe
Richard J. Barohn
Steven L. Galetta
73. Sodium Fluorescein and Other Tissue Dyes	849	(16)
R. Nick Hogan
Carol F. Zimmerman
Subject Index	865