Textbook of Pediatric HIV Care

by Edited by Steven L. Zeichner , Jennifer S. Read

• ISBN13: 9780521821537
• ISBN10: 0521821533
• Format: Hardcover
• Copyright: 2005-06-13
• Publisher: Cambridge University Press

Summary

This comprehensive textbook provides the definitive account of effective care for pediatric HIV patients. Drawing on the massive and burgeoning published literature from a wide range of sources, this volume summarises a wealth of information concerning the aetiology of the disease and the best clinical care for this vulnerable group. It distils the very latest knowledge of virology, immunology and pathogenesis and uses this to illuminate and explain management recommendations. Recently, many new agents for the treatment and prophylaxis of HIV infection and the opportunistic infections that accompany HIV infection have been developed, accompanied by many new ways of monitoring HIV infection in children. These new therapies and approaches to management are complicated, but the long-term health of HIV-infected children depends on their meticulously correct application. This textbook explains, helps and guides the clinician through all these complexities to facilitate the best possible care for children with HIV infection.

Table of Contents

Foreword Cathy Wilfert

List of contributors

Preface

Introduction

Part I. Scientific Basis of Pediatric HIV Care: 1. Normal development and physiology of the immune system Sherlyn Smith and Ann J. Melvin

2. HIV basic virology for clinicians Steven L. Zeichner

3. Immunology of pediatric HIV disease/infection Elizabeth J. McFarland

4. Clinical virology of pediatric HIV disease/infection Paul Palumbo

5. Natural history of pediatric HIV disease/infection Grace M. Aldrovandi

6. Epidemiology of pediatric HIV disease/infection Mary Lou Lindegren

Part II. General Issues in the Care of Pediatric HIV Patients: 7. Diagnosis of HIV infection Paul Krogstad

8. Prevention of mother-to-child/vertical transmission of HIV Jennifer S. Read

9. Routine pediatric care Elaine Abrams and Lisa-Gaye Robinson

10. Immunizations Rachel Y. Moon

11. Prophylaxis for opportunistic infections Russell B. Van Dyke

12. Emergency evaluation and care James M. Callahan

13. Adherence to therapy in pediatric HIV disease John Farley

14. Adolescents and HIV Bret R. Rudy

15. Gynecology of the HIV-infected adolescent Ligia Peralta and Sandra Cely

16. Growth, nutrition and metabolism Caroline J. Chantry and Jack Moye Jr

17. Neurodevelopmental/neurobehavioral function and assessment of children with HIV-1 infection Pamela L. Wolters and Pim Brouwers

Part III. Antiretroviral Therapy: 18. Antiretroviral therapy Ross McKinney Jr

19. Antiretroviral drug interactions Thomas N. Kakuda and Courtney V. Fletcher

20. Metabolic complications of antiretroviral therapy Carol J. Worrell

21. Assessment and management of resistance to antiretroviral therapy Frank Maldarelli

22. Initiating and changing antiviral therapy Lynne M. Mofenson and Leslie K. Serchuck

23. Therapeutic drug monitoring Stephen C. Piscitelli

24. HIV post-exposure prophylaxis for pediatric patients Kenneth L. Dominguez

Part IV. Clinical Manifestations of HIV Infection in Children: 25. Dermatological problems in HIV-infected children Andrew Blauvelt

26. Neurologic problems Lucy Civitello

27. Ophthalmologic problems in the HIV-infected child

Howard F. Fine, Susan S. Lee and Michael R. Robinson

28. Oral health and dental problems (in the HIV-infected child) Jane C. Atkinson

29. Otitis media and sinusitis Ellen R. Wald and Barry Dashefsky

30. Cardiac problems Gul H. Dadlani and Steven E. Lipshultz

31. Pulmonary problems Lauren V. Wood

32. Hematologic problems William C. Owen and Eric J. Werner

33. Gastrointestinal disorders Harland S. Winter and Jack Moye

34 Renal disease in pediatric HIV infection Somsak Tanawattanacharoen and Jeffrey B. Kopp

35. Endocrinologic problems Daina Dreimane and Mitchell E. Geffner

36. Neoplastic disease in pediatric HIV infection Richard F. Little

Part V. Infectious Problems in Pediatric HIV Disease: 37. Typical bacterial infections Shirley Jankelevich

38. Tuberculosis Rohan Hazra

39. Atypical mycobacteria Robert N. Husson

40 Fungal infections Corina E. Gonzalez

41. Herpesvirus infections Richard M. Rutstein and Stuart E. Starr

42. Pneumocystis carinii (PCP) Leslie K. Serchuck

Part VI. Medical Social and Legal Issues: 43. Clinical trials for HIV infected children James McNamara

44 Medical issues related to the care for HIV-infected children in the home, day care, school, and community Stephen J. Chanock

45. Contact with social service agencies Sandra Y. Lewis and Heidi J. Haiken

46. Disclosure Lori S. Wiener

47. Bereavement Lori S. Wiener

48. Legal issues for HIV-infected children Carolyn McAllaster

Appendices

Formulary/drug ready reference Paul Jarosinki

NIH-sponsored clinical trials for pediatric HIV disease James McNamara

Online resources Leslie K. Serchuck

Legal appendix Carolyn McAllaster

Index.