Textbook of Pharmacoepidemiology

by Strom, Brian L.; Kimmel, Stephen E

• ISBN13: 9780470029251
• ISBN10: 0470029250
• Edition: 1st
• Format: Paperback
• Copyright: 2007-01-23
• Publisher: WILEY

Summary

The Textbook of Pharmacoepidemiology provides a streamlined text for evaluating the safety and effectiveness of medicines. It includes a brief introduction to pharmacoepidemiology as well as sections on data sources, methodology and applications. Each chapter includes key points, case studies and essential references. One-step resource to gain understanding of the subject of pharmacoepidemiology at an affordable price Gives a perspective on the subject from academia, pharmaceutical industry and regulatory agencies Designed for students with basic knowledge of epidemiology and public health Includes many case studies to illustrate pharmacoepidemiology in real clinical setting

Author Biography

Brian L. Strom, University of Pennsylvania School of Medicine, USA. 

Stephen E. Kimmel, Associate Professor of Medicine and Epidemiology, University of Pennsylvania School of Medicine, USA.

Table of Contents

List of Contributors	p. ix
Preface	p. xiii
Acknowledgments	p. xv
Acknowledgments from Pharmacoepidemiology, Fourth Edition	p. xvii
Introduction to Pharmacoepidemiology	p. 1
What is Pharmacoepidemiology?	p. 3
Study Designs Available for Pharmacoepidemiology Studies	p. 13
Sample Size Considerations for Pharmacoepidemiology Studies	p. 25
Basic Principles of Clinical Pharmacology Relevant to Pharmacoepidemiology Studies	p. 35
When Should One Perform Pharmacoepidemiology Studies?	p. 55
Views from Academia, Industry, and Regulatory Agencies	p. 63
Sources of Pharmacoepidemiology Data	p. 89
Spontaneous Reporting in the United States	p. 91
Global Drug Surveillance: The WHO Programme for International Drug Monitoring	p. 117
Case-Control Surveillance	p. 137
Prescription-Event Monitoring	p. 151
Overview of Automated Databases in Pharmacoepidemiology	p. 167
Examples of Automated Databases	p. 173
Other Approaches to Pharmacoepidemiology Studies	p. 215
How Should One Perform Pharmacoepidemiology Studies? Choosing Among the Available Alternatives	p. 227
Validity of Pharmacoepidemiologic Drug and Diagnosis Data	p. 239
Special Issues in Pharmacoepidemiology Methodology	p. 259
Bias and Confounding in Pharmacoepidemiology	p. 261
Determining Causation from Case Reports	p. 277
Molecular Pharmacoepidemiology	p. 287
Bioethical Issues in Pharmacoepidemiologic Research	p. 301
The Use of Randomized Controlled Trials for Pharmacoepidemiology Studies	p. 311
The Use of Pharmacoepidemiology to Study Beneficial Drug Effects	p. 321
Pharmacoeconomics: Economic Evaluation of Pharmaceuticals	p. 333
Using Quality-of-Life Measurements in Pharmacoepidemiologic Research	p. 345
The Use of Meta-analysis in Pharmacoepidemiology	p. 353
Patient Adherence to Prescribed Drug Dosing Regimens in Ambulatory Pharmacotherapy	p. 367
Novel Approaches to Pharmacoepidemiology Study Design and Statistical Analysis	p. 383
Special Applications of Pharmacoepidemiology	p. 397
Special Applications of Pharmacoepidemiology	p. 399
The Future of Pharmacoepidemiology	p. 447
Sample Size Tables	p. 455
Glossary	p. 473
Index	p. 481
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