Tietz Textbook of Clinical Chemistry and Molecular Diagnostics

by Burtis, Carl A.

• ISBN13: 9781416061649
• ISBN10: 1416061649
• Edition: 5th
• Format: Hardcover
• Copyright: 2011-12-01
• Publisher: SAUNDERS W B CO

Summary

As the definitive reference for clinical chemistry, Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 5th Edition offers the most current and authoritative guidance on selecting, performing, and evaluating results of new and established laboratory tests. Up-to-date encyclopedic coverage details everything you need to know, including: analytical criteria for the medical usefulness of laboratory procedures; new approaches for establishing reference ranges; variables that affect tests and results; the impact of modern analytical tools on lab management and costs; and applications of statistical methods. In addition to updated content throughout, this two-color edition also features a new chapter on hemostasis and the latest advances in molecular diagnostics. Section on Molecular Diagnostics and Genetics contains nine chapters that focus on emerging issues and techniques. Highly-respected author team includes three editors who are well known in the clinical chemistry world. Reference values in the appendix give you one location for comparing and evaluating test results. Companion Evolve website includes appendix material and book references linked to PubMed. NEW! Two-color design throughout highlights important features, illustrations, and content for a quick reference. NEW! Chapter on hemostasis provides you with all the information you need to accurately conduct this type of clinical testing. NEW! Six associate editors lend even more expertise and insight to the reference. NEW! Reorganized chapters ensure that only the most current information is included.

Table of Contents

: Principles of Laboratory Medicine

Introduction to Laboratory Medicine

Selection and Analytical Evaluation of Methods - With Statistical Techniques

Clinical Evaluation of Methods

Evidence Based Laboratory Medicine

Establishment and Use of Reference Values

Preanalytical Variables and Biological Variation

Specimen Collection and Processing

Quality Management

: Analytical Techniques and Instrumentation

Principles of Basic Techniques and Laboratory Safety

Optical Techniques

Electrochemistry and Chemical Sensors

Electrophoresis

Chromatography and Extraction

Mass Spectrometry

Enzyme and Rate Analyses

Principles of Immunochemical Techniques

Nucleic Acid Techniques

Microfabrication and Microfluidics and Their Application to Clinical Diagnostics

Automation in the Clinical Laboratory

Point-of-Care Testing

: Analytes

Amino Acids, Peptides, and Proteins

Serum Enzymes

Enzymes of the Red Blood Cell

Tumor Markers

Kidney Function Tests

Carbohydrates

Lipids, Lipoproteins, Apolipoproteins, and Other Cardiovascular Risk Factors

Electrolytes and Blood Gases

Hormones

Catecholamines and Serotonin

Vitamins and Trace Elements

Hemoglobin, Iron, and Bilirubin

The Porphyrias and Other Disorders of Porphyrin Metabolism

Therapeutic Drugs and Their Management

Clinical Toxicology

Toxic Metals

: Molecular Diagnostics and Genetics

Principles of Molecular Biology

Genomes and Nucleic Acid Alterations

Nucleic Acid Isolation

Inherited Diseases

Identity Assessment

Molecular Methods in Diagnosis and Monitoring of Infectious Diseases

Pharmacogenetics

Hematopoietic Malignancies

Plasma Nucleic Acids

: Pathophysiology

Diabetes Mellitus

Cardiovascular Disease

Kidney Disease

Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism

Liver Disease

Gastrointestinal and Pancreatic Diseases

Disorders of Bone and Mineral Metabolism

Pituitary Function and Pathophysiology

The Adrenal Cortex

The Thyroid: Pathophysiology and Thyroid Function Testing

Reproductive Endocrinology and Related Disorders

Pregnancy and its Disorders

Newborn Screening and Inborn Errors of Metabolism

Hemostasis

: Appendix

Reference Information for the Clinical Laboratory

Table of Contents provided by Publisher. All Rights Reserved.