Tietz's Applied Laboratory Medicine

by Scott, Mitchell G.; Gronowski, Ann M.; Eby, Charles S.

• ISBN13: 9780471714576
• ISBN10: 0471714577
• Edition: 2nd
• Format: Paperback
• Copyright: 2007-02-26
• Publisher: Wiley-Liss

Summary

Using a problem-based approach, Tietz's Applied Laboratory Medicine, Second Edition presents interesting cases to illustrate the current use and interpretation of the most commonly available clinical laboratory tests. The cases present detailed descriptions of the symptoms, diagnosis, and treatment of disease. The book begins with an up-to-date general discussion of selection and use of laboratory diagnostic and prognostic tests. Cases are then grouped by category, including cardiovascular, pulmonary, renal, liver, gastrointestinal, endocrine, gynaecologic & obstetrical, haematological, CNS, lipid, congenital, toxicological, infectious, and autoimmune diseases.Tietz's Applied Laboratory Medicine, Second Edition: Presents over 100 cases organised by disease group Reflects latest treatment and risk factor guidelines, testing algorithms and recommendations Newly covers coagulopathies, infectious diseases, and autoimmune diseases Provides excellent coverage of relevant pathophysiology and biochemistry, and includes cases in molecular diagnostics Discusses legal implicationsThis book is an invaluable resource for all clinical chemists, clinical lab technologists, pathologists, and allied health professionals. It is also of interest for general practitioners, residents, medical students, and educators.

Author Biography

MITCHELL G. SCOTT, PhD, is Professor of Pathology and Immunology in the Division of Laboratory Medicine, Department of Pathology and Immunology at Washington University and Co-Medical Director of Clinical Chemistry at Barnes-Jewish Hospital, St. Louis, Missouri. He served as president of the American Association for Clinical Chemistry in 2005.

ANN M. GRONOWSKI, PhD, is Associate Professor of Pathology & Immunology and Obstetrics & Gynecology, Division of Laboratory Medicine, Washington University and Associate Medical Director, Clinical Chemistry and Serology at Barnes-Jewish Hospital.

CHARLES S. EBY, MD, is Associate Professor of Pathology & Immunology and Medicine, Division of Laboratory Medicine and Hematology at Washington University and Medical Director, Hematology and Coagulation, Barnes-Jewish Hospital.

Table of Contents

Preface	p. xi
Contributors	p. xiii
Cardiac Disease
A 45-Year-Old Man with Substantial Chest Pain	p. 3
A 48-Year-Old Cocaine User with Chest Pain	p. 11
Pulmonary Diseases
Shortness of Breath with Productive Cough	p. 19
Genotype-Phenotype Correlations in Cystic Fibrosis	p. 25
Renal Disease
Man with Hypertension and Fever	p. 33
Oliguria with Metabolic Acidosis after Renal Transplantation	p. 41
A Woman with Uremia, Pulmonary Infiltration, and Hemoptysis	p. 49
Young Man with Edema and Decreased Urine Output	p. 55
A New Doctor for a Man with Diabetes and Hypertension	p. 65
A Pain in the Back	p. 75
Refractory Hyponatremia with Lung Cancer	p. 79
Liver Diseases
Adolescent Female with Tremor, Depression, and Hepatitis	p. 91
Adult Male with New-Onset Ascites	p. 99
An Unexpected Finding...	p. 105
I Did It Just Once-A 37-Year-Old Man with Hepatitis C	p. 111
Obese Woman with Persistently Abnormal Liver Enzymes	p. 121
Thyroid Diseases
The Irritable Wife	p. 131
The Fatigued Attorney	p. 139
The Reluctant Chef	p. 143
Adrenocortical Diseases
Child with Rapid Growth and Precocious Sexual Maturation	p. 149
Weight Gain, Infertility, and Hypertension	p. 155
The Tired Teenager	p. 167
The Hypertensive Accountant	p. 175
Don't "Take Two Aspirin and Call Me in the Morning"	p. 183
Unpleasant Spells	p. 189
Diabetes
Recent Weight Loss and Polyuria in a 52-Year-Old Man	p. 199
An Unconscious Diabetic Male	p. 205
A Diabetic Woman's "Episode"	p. 211
Calcium and Parathyroid Hormone (PTH)
Bad to the Bone	p. 219
A Middle-Aged Woman with Colle's Fracture	p. 225
A 10-Year-Old Boy with Pain-Induced Seizures	p. 233
Miscellaneous Endocrine Diseases
Laboratory Tests Ignored	p. 243
Hot Flashes and Abdominal Pain	p. 249
Genetically Inherited Disorders
Feed a Cold	p. 257
Acute Neonatal Ammonia Intoxication	p. 263
Not Just a Picky Eater	p. 269
The "Fussy" Neonate	p. 275
The "Sleepy" Neonate	p. 281
A Happy but Developmentally Delayed 5-Year-Old Boy	p. 287
The Asymptomatic Iron Man	p. 293
Infectious Diseases
Tired, Hot, and Lumpy	p. 301
A Rash on the Soles of the Feet	p. 305
When Life Gives You Lemons	p. 311
The Wheezing Woodsman	p. 315
Not Just Heartburn	p. 319
The Dangers of Yardwork	p. 329
Nonhematologic Malignancies
An Important Finding on Routine Screening	p. 337
Increasing Abdominal Girth	p. 343
To Screen or Not to Screen?	p. 349
A Male with Confusing hCG Results	p. 355
Size Greater than Dates	p. 363
Hematologic Malignancies
A Man with Anemia and Lymphocytosis	p. 371
A Teenager with Pneumonia, Leukopenia, and Ecchymoses	p. 379
A Middle-Aged Man with Chronic Foot Ulcer	p. 387
A Man with Progressive Effort Intolerance and Splenomegaly	p. 393
A Man with Splenic Vein Thrombosis and Polycythemia	p. 401
Benign Hematologic Disorders
A Child with Pneumonia	p. 411
A Man with a Tender Toe and Anemia	p. 419
A Woman with Fatigue and Pallor	p. 425
Pulseless Leg 9 Days after a Myocardial Infarction	p. 435
Young Girl with a Bloody Knee Effusion	p. 443
A Young Man with Chest Pain Following a Knee Injury	p. 453
A Young Woman with Postpartum Cerebral Venous Thrombosis and Abnormal Coagulation Tests	p. 459
A Baby with Petechiae and Bruises	p. 465
Evaluation of a Reference Range Outlier	p. 475
A Woman with Abdominal Pain and Thrombocytopenia	p. 485
Sudden Jaundice and Painful Fingers	p. 491
The Good in "Bad" Fish Tacos	p. 497
The Jaundiced Mother	p. 503
Porphyrias
Young Woman with Recurrent Abdominal Pain	p. 513
A 9-Year-Old Boy with Skin Lesions and Headaches	p. 523
Pharmacogenomics
Personalized Medicine for a Renal Transplant Patient	p. 533
Personalized Medicine for Pain Management	p. 539
A Man with Colitis and Pancytopenia	p. 543
A 46-Year-Old Female with a Painful, Swollen Right Calf	p. 551
Toxicology
A Case of Mixed Club Drugs Abuse	p. 557
A 43-Year-Old Male with Chronic Pain	p. 561
Metabolic Acidosis of Unknown Origin Among Burn Patients	p. 567
Lipid Disorders
The Family Reunion Party	p. 575
A 5-Year-Old Boy with Yellow-Orange Tonsils: Hypoalphalipoproteinemia	p. 581
Worsening Diarrhea in a 5-Year-Old Girl	p. 585
A 4-Year-Old Girl with Yellow Xanthomas and Arthritis	p. 589
Autoimmune Diseases
Woman with Morning Stiffness and Tender, Swollen Joints	p. 595
Woman with a Rash and Lower Extremity Pain	p. 601
Woman with Diarrhea and Anemia	p. 609
Analytical Errors
Where's My Baby?	p. 617
Elevated Concentrations, but Not Elevated Enough	p. 623
I Want To Go Home!	p. 629
Is That Really the Calcium Value?	p. 635
Miscellaneous
A Man with Fever and Acute Polyarthritis	p. 643
Middle-Aged Alcoholic with Jaundice and Ascites	p. 649
Where Did the Red Cells Go?	p. 658
Index	p. 665
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