Preface | |
Basic Principles of Gene Transfer in Hematopoietic Stem Cells | p. 1 |
Optimizing Conditions for Gene Transfer into Human Hematopoietic Cells | p. 20 |
Transfer of the MDR-1 Gene into Hematopoietic Cells | p. 50 |
Ove Hematopoietic Cell Tolerance to Alkylating Agents | p. 65 |
Use of Variants of Dihydrofolate Reductase in Gene Transfer to Produce Resistance to Methotrexate and Trimetrexate | p. 82 |
Augmentation of Methotrexate Resistance with Coexpression of Metabolically Related Genes | p. 95 |
Protection of Bone Marrow Cells from Toxicity of Chemotherapeutic Agents Targeted toward Thymidylate Synthase by Transfer of Mutant Forms of Human Thymidylate Synthase cDNA | p. 107 |
Dihydropyrimidine Dehydrogenase and Resistance to 5-Fluorouracil | p. 115 |
Chemoprotection against Cytosine Nucleoside Analogs Using the Human Cytidine Deaminase Gene | p. 124 |
In vivo Selection of Hematopoietic Stem Cells Transduced with DHFR-Expressing Retroviral Vectors | p. 143 |
In vivo Selection of Genetically Modified Bone Marrow Cells | p. 162 |
Gene Transfer in the Nonmyeloablated Host | p. 172 |
Author Index | p. 179 |
Subject Index | p. 180 |
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