Translational Research and Clinical Practice Basic Tools for Medical Decision Making and Self-Learning

by Aronoff, Stephen C.

• ISBN13: 9780199746446
• ISBN10: 0199746443
• Edition: 1st
• Format: Paperback
• Copyright: 2010-11-17
• Publisher: Oxford University Press

Summary

Translational Research and Clinical Practice offers a clear and comprehensive introduction to evidence-based medicine. The use of medical literature has always been an integral tool for patient care, yet recently the modern processes of question formulation, literature search, and study evaluation have changed with the advent of the internet and technology. The physician must be able to find empirical evidence from the appropriate study using a searchable question and then determine its impact on patient care. The book provides the general framework for such medical decision making; it covers all kinds of cases and strategies, including questions of diagnosis, therapy, prognosis, differential diagnosis, clinical presentation, and causality. The tested material and approaches in this book are based on a course developed and taught by the author at Temple University School of Medicine. Organized for ease of use, accessibly written, and replete with clinically germane examples, Translational Research and Clinical Practice is a concise guide for medical students and clinicians seeking to effectively interpret and apply medical evidence in daily practice.

Author Biography

Waldo E. Nelson Professor and Chair, Department of Pediatrics, Temple University School of Medicine, Philadelphia, Pennsylvania

Table of Contents

Preface	p. vii
Developing a Clinical Question and Searching the Medical Literature	p. 3
The Anatomy of a Clinical Study	p. 7
Designs of Clinical Studies	p. 15
Lies, More Lies, and Statistics (With Apologies to Mark Twain)	p. 21
Answering a Question Regarding the Treatment of a Disease	p. 31
Answering a Question Regarding the Utility of a Diagnostic Test	p. 39
Answering a Question Regarding Prognosis and Risk Factors	p. 49
Answering a Question Using a Clinical Prediction Rule	p. 55
Answering a Question about Etiology or Differential Diagnosis	p. 63
Using Medical Evidence to Answer a Question Regarding Clinical Presentation	p. 67
Using Meta-Analyses to Answer a Question of Diagnosis and Therapy	p. 73
Answering a Question Regarding Causation	p. 83
Clinical Guidelines: Prepackaged Medical Decision Making	p. 89
Putting It All Together	p. 95
Developing a Plan for Lifelong Education	p. 121
Teaching Medical Decision Making	p. 127
Index	p. 133
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