Transport of Molecules Across Microbial Membranes

by Edited by J. K. Broome-Smith , S. Baumberg , C. J. Stirling , F. B. Ward

• ISBN13: 9780521772709
• ISBN10: 0521772702
• Edition: 1st
• Format: Hardcover
• Copyright: 1999-10-28
• Publisher: Cambridge University Press

Summary

This volume considers the transport of molecules, large and small, across the membranes of prokaryotic and eukaryotic microbial cells. A diverse range of related phenomena are covered, but the unifying themes are the signal peptides that target proteins to particular destinations, and the role of chaperonins. Topics covered include: secretion of proteins out of the bacterial cell by Type I, II and III mechanisms, including the newly recognised bacterial signal recognition pathway in Type II; passage across internal membranes of eukaryotic proteins, whether destined for secretion or en route to internal organelles such as chloroplasts and peroxisomes; how bacteria obtain the energy required for solute uptake, the role of phosphorylation, and evolutionary relationships of some of the proteins involved; and efflux pumps for toxic substances in bacterial, animal and plant cells.

Table of Contents

Contributors	vii
Overview: Transport of molecules across microbial membranes - a sticky business to get to grips with	1	(14)
J. K. Broome-Smith
C. Mitsopoulos
Multidrug resistance efflux	15	(26)
K. Lewis
Regulation of solute accumulation in bacteria and its physiological significance	41	(17)
B. Poolman
Arsenic transport systems from Escherichia coli to humans	58	(22)
H. Bhattacharjee
M. Ghosh
R. Mukhpadhyay
B. P. Rosen
Type II protein secretion: the main terminal branch of the general secretory pathway	80	(30)
A. Filloux
Type III secretion and the pathogenesis of Yersinia infections	110	(14)
D. M. Anderson
L. W. Cheng
V. T. Lee
S. Masmanian
K. Ramamurthi
C. Tam
O. Schneewind
Assembly of bacterial adhesins across the outer membrane via the chapterone--usher pathway	124	(14)
G. E. Soto
S. J. Hultgren
DNA uptake by transformable bacteria	138	(31)
S. A. Lacks
Escherichia coli signal recognition particle - a historical perspective	169	(17)
Q. A. Valent
E. N. S. O'Gorman
P. Scotti
J. Luirink
S. High
Protein translocation into the endoplasmic reticulum	186	(18)
B. P. Young
J. K. Brownsword
C. J. Stirling
Peroxisome biogenesis	204	(35)
E. Lopez-Huertas
A. Baker
Transport of proteins into and across the thylakoid membrane	239	(13)
C. Robinson
W. Edwards
P. J. Hynds
C. Tissier
Evolutionary origins of transmembrane transport systems	252	(23)
M. H. Saier, Jr
T.-T. Tseng
Index	275