The Treatment of Epilepsy, 3rd Edition

by Editor: Simon D. Shorvon (Institute of Neurology, University College London); Editor: Emilio Perucca (University of Pavia, Italy); Editor: Jerome Engel (University of California at Los Angeles, USA)

• ISBN13: 9781444316674
• ISBN10: 1444316672
• Format: eBook
• Copyright: 2009-07-01
• Publisher: Wiley-Blackwell

Summary

A practical reference to the medical and surgical treatment of epilepsyThe third edition of The Treatment of Epilepsy has been thoroughly updated. It is a reference work, but has a strong practical bias, and is designed to assist neurologists, neurosurgeons and other clinicians at all levels who are involved in the treatment of patients with epilepsy. It is a definitive source of clinical information to guide clinical practice and rational therapy.Written and edited by leading experts, many actively involved with the International League Against Epilepsy, this new edition: covers the recent advances in the principles and approaches to epilepsy therapy, the introduction of new drugs and the development of new surgical techniques contains 26 completely new chapters and 61 new contributors includes pharmacological properties and prescribing information for all drugs used in the treatment of epilepsy features the important contribution of a new editor Jerome Engel Jr, Professor of Neurology at the University of California School of Medicine in Los Angeles.

Table of Contents

Introduction

Definitions and Classification of Epilepsy

Epidemiology and Prognosis of Epilepsy

Aetiology of Epilepsy

Differential Diagnosis of Epilepsy

Mechanisms of Epileptogenesis

Antiepileptic Drug Discovery

Mechanisms of Antiepileptic Drug Action

Mechanisms of Tolerance and Drug Resistance

Principles of Medical Management

General Principles of Medical Management

Management of Newly Diagnosed Epilepsy

Management of Chronic Active Epilepsy in Adults

Management of Epilepsy in Remission

Management of Epilepsy in Infants

Management of Childhood Epilepsy Syndromes

Management of Epilepsies Associated with Specific Diseases in Children

Management of Epilepsy in the Elderly

Management of Epilepsy in People with Learning Disabilities

Emergency Treatment of Seizures and Status Epilepticus

Traumatic Brain Injury and Other Risks

Management of Medical Co-morbidity Associated with Epilepsy

Psychiatric Features of Epilepsy and their Management

Management of Side-effects of Antiepileptic Drugs

Ketogenic Diets

Non-pharmacological, Complementary and Alternative Treatments for Epilepsy

Reproductive Aspects of Epilepsy Treatment

Epilepsy Counselling

Genetic Counselling in Epilepsy

Drug Interactions

Medical Treatment of Epilepsy in Situations with Limited Resources

Antiepileptic Drugs

Introduction to the Choice of Antiepileptic Drugs

Acetazolamide

Adrenocorticotropic Hormone and Corticosteroids

Benzodiazepines used Primarily for Chronic Treatment (Clobazam, Clonazepam, Clorazepate and Nitrazepam)

Benzodiazepines used Primarily for Emergency Treatment (Diazepam, Lorazepam and Midazolam)

Brivaracetam

Carisbamate

Carbamazepine

Eslicarbazepine Acetate

Ethosuximide

Felbamate

Gabapentin

Lacosamide

Lamotrigine

Levetiracetam

Oxcarbazepine

Phenobarbital, Primidone and Other Barbiturates

Phenytoin

Piracetam

Pregabalin

Retigabine

Rufinamide

Stiripentol

Tiagabine

Topiramate

Valproate

Vigabatrin

Zonisamide

Other Drugs Rarely Used

Antiepileptic Drugs in Early Clinical Development

Presurgical Assessment and Epilepsy Surgery

Overview of Surgical Treatment for Epilepsy

Scalp EEG in the Epilepsy Surgery Evaluation

Invasive EEG in Presurgical Evaluation of Epilepsy

MEG in Presurgical Evaluation of Epilepsy

MRI in the Presurgical Evaluation

PET and SPECT in Presurgical Evaluation of Epilepsy

Experimental Neurophysiological Techniques

Neuropsychological Testing in Presurgical Evaluation

Presurgical Psychiatric Evaluation

Mesial Temporal Lobe Surgery and Other Lobar Resections

Resective Surgery of Neoplasms

Resective Surgery of Vascular and Infective Lesions for Epilepsy

Surgery of Developmental Anomalies Causing Epilepsy

Hemispherectomy for Epilepsy

Corpus Callosotomy

Hypothalamic Hamartoma and Multiple Subpial Transection

Awake Surgery for Epilepsy

Epilepsy Surgery in Children

Stereotactic Surgery for Epilepsy

Complications of Epilepsy Surgery

Anaesthesia for Epilepsy Surgery

Vagal Nerve Stimulation

Brain Stimulation

Stereotactic Radiosurgery for Medically Intractable Epilepsy

Future Focal Treatment Approaches to Epilepsy

Epilepsy Surgery in Countries with Limited Resources

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