Type 1 Diabetes

by Sperling, Mark A., M.D.

• ISBN13: 9780896039315
• ISBN10: 0896039315
• Format: Hardcover
• Copyright: 2003-06-01
• Publisher: Humana Pr Inc

Summary

A concise survey by physicians and researchers of the latest thinking about the causes of diabetes and the best approaches to treating its acute and chronic complications. The authors pay special attention to explaining the molecular basis of diabetes and its complications, as well as to the many recent developments in whole pancreas and islet cell transplantation, including the means for avoiding the rejection of transplanted islets.

Table of Contents

Preface	v
Contributors	xi
I. Etiology
Epidemiology of Type 1 Diabetes	3	(20)
Janice S. Dorman
Ronald E. LaPorte
Thomas J. Songer
Genetics of Type 1 Diabetes	23	(32)
Massimo Pietropaolo
Massimo Trucco
Prediction and Prevention of Type 1 Diabetes	55	(16)
Aristides K. Maniatis
George S. Eisenbarth
Molecular Biology of β-Cell Destruction by Autoimmune Processes	71	(22)
Åke Lernmark
Choon Hee Chung
Type 1 Diabetes in Autoimmune Syndromes	93	(22)
Tiinamaija Tuomi
Jaakko Perheentupa
The Metabolic Basis of Insulin Secretion	115	(30)
Nicolai M. Doliba
Franz M. Matschinsky
Prevention and Correction of Hypoglycemia: Relevance to Type 1 Diabetes	145	(18)
Philip E. Cryer
Nonautoimmune Forms of Diabetes: Neonatal Diabetes, DIDMOAD--Wolfram Syndrome, and Related Syndromes	163	(20)
Timothy G. Barrett
II. Treatment of Type 1 Diabetes
Diabetic Ketoacidosis	183	(16)
Ram K. Menon
Mark A. Sperling
Insulin Regimens for Type 1 Diabetes	199	(16)
Baiju R. Shah
Bernard Zinman
Relationship Between Metabolic Control and Complications in Diabetes: Therapeutic Implications of the Diabetes Control and Complications Trial	215	(18)
Saul Genuth
Open- and Closed-Loop Insulin Delivery Systems and Glucose Sensors	233	(16)
John C. Pickup
Living with Diabetes: Educating the Patient and Family with Type 1 Diabetes	249	(12)
Jean Betschart Roemer
Linda Siminerio
Nutritional Management in Type 1 Diabetes	261	(18)
Christine A. Beebe
III. Special Management Issues in Type 1 Diabetes
Special Problems and Management of the Child Less Than 5 Years of Age	279	(14)
Nadia Tubiana-Rufi
Paul Czernichow
The Preadolescent Child with Type 1 Diabetes	293	(14)
William V. Tamborlane
Elizabeth A. Boland
Margaret Grey
The Adolescent with Type 1 Diabetes	307	(14)
George A. Werther
Fergus J. Cameron
John M. Court
Hypoglycemia in Type 1 Diabetes	321	(24)
Stephanie A. Amiel
Krystyna Matyka
Pregnancy and Type 1 Diabetes	345	(16)
Erica M. Sommermann
Erin K. Van Meter
Lois Jovanovic
Surgery for the Patient with Type 1 Diabetes	361	(14)
Adrian Vella
Robert A. Rizza
IV. Long--Term Complications of Type 1 Diabetes
Biochemistry and Molecular Biology of Diabetic Complications	375	(18)
Kenya Sakamoto
Michael Brownlee
The Eye: Diabetic Retinopathy/Ophthalmopathy	393	(16)
David Kent
Peter A. Campochiaro
The Kidney: Diabetic Nephropathy	409	(28)
Abhay Vats
Frederick DeRubertis
Diabetic Peripheral and Autonomic Neuropathy	437	(26)
Eva L. Feldman
Martin J. Stevens
James W. Russell
The Diabetic Foot	463	(10)
David L. Steed
Atherosclerosis in Type 1 Diabetes	473	(12)
Wael Emad Eid
Siripoom McKay
Finnbogi Karlsson
Alan J. Garber
Cutaneous Complications of Type 1 Diabetes	485	(16)
Jean L. Bolognia
Irwin M. Braverman
Infection and Diabetes	501	(16)
Nirmal Joshi
Pancreas Transplantation	517	(12)
R. Paul Robertson
Islet Transplantation	529	(24)
Thierry Berney
Norma Sue Kenyon
Rodolfo Alejandro
Luca Inverardi
Daniel H. Mintz
Camillo Ricordi
β--Cell Replacement Therapy for Type 1 Diabetes	553	(8)
Shimon Efrat
Islet Growth Factors	561	(18)
Rupangi C. Vasavada
Adolfo Garcia-Ocana
Karen K. Takane
Ana Cebrian
Juan Carlos Lopez-Talavera
Andrew F. Stewart
Index	579