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9780306456497

Ubiquitin and the Biology of the Cell

by ; ;
  • ISBN13:

    9780306456497

  • ISBN10:

    0306456494

  • Format: Hardcover
  • Copyright: 1998-06-01
  • Publisher: Plenum Pub Corp
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List Price: $279.99

Summary

Research Institute of Molecular Pathology, Vienna, Austria. Text addressing the importance of ubiquitin-dependent proteolysis as a regulatory mechanism. Recounts the work that led to this new perception. For researchers and students in the field of cell biology, signal transduction, protein sorting, neuropathology, oncology, and virology. Modified-outline format.

Table of Contents

The Ubiquitin System: Past, Present and Future Perspectives
Polyubiquitin Chains
The Ibiquitin-Conjugation System
The Deubiquitinating Enzymes
The 20S Proteasome
The 26S Proteasome
Function of the Proteasome in Antigen Presentation
The N-end Rule Pathway
Ubiquitin-Dependent Degradation of Transcriptional Regulators
Role of the Ubiquitin-Proteasome Pathwayi in Nf-KB Activation
Ubiquitination of the 053 Tumor Suppressor
Ubiquitination of Integral Membrane Proteins and Proteins in the Secretory Pathway
Degradation of Ornithine Decarboxylase
Ubiquitin and the Molecular Pathology of Human Disease
Index
Table of Contents provided by Publisher. All Rights Reserved.

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