Vaccine Design

by Gregoriadis, Gregory; McCormack, Brenda; Allison, Anthony C.

• ISBN13: 9780306458187
• ISBN10: 0306458187
• Format: Hardcover
• Copyright: 1997-11-01
• Publisher: Plenum Pub Corp

Summary

Univ. of London, U.K. Proceeding of a NATO Advanced Study Institute on Vaccine Design: The Role of Cytokine Networks, held June 24-July 5, 1996, in Cape Sounion, Greece. 60 contributors, 6 U.S.

Table of Contents

The Role of Cytokines in the Action of Immunological Adjuvants	1	(10)
Anthony C. Allison
The Role of Tumour Necrosis Factor in Lymphoid Tissue Formation and Function	11	(8)
Manolis Pasparakis
Eleni Douni
Lena Alexopoulou
George Kollias
Dendritic Cells and Cytokines	19	(6)
Jonathan M. Austyn
Control of HIV Entry and Transcription, as a Possible Mechanism of the Antiviral Effects of T Lymphocytes in HIV Infection	25	(8)
J.-L. Virelizier
A. Amara
E. Oberlin
D. Rousset
M. Rodriguez
M. Kroll
Development of an Influenza-Iscom(TM) Vaccine	33	(18)
John Cox
Alan Coulter
Rod Macfarlan
Lorraine Beezum
John Bates
Tuen-Yee Wong
Debbie Drane
Development of Parainfluenza Virus and Respiratory Syncytial Virus Subunit Vaccines	51	(8)
M. Ewasyshyn
G. Cates
G. Jackson
A. Symington
N. Scollard
R. P. Du
M. Klein
Mucosal Vaccines: Perspectives on the Development of Anti-H.pylori Vaccines	59	(8)
Paolo Ghiara
A Single Treatment with Adjuvant Stimulates Th1-like Cytokines and Downregulates Th2-Mediated Primary and Secondary Allergic Responses	67	(14)
Dorothy E. Scott
Basil Golding
Induction of IL-12 Secretion and Enhanced Surface Expression of B7.1/B7.2 and ICAM-1 in Human Monocytes Activated by the Vaccine Carrier Brucella abortus: Correlation with in Vivo Generation of Cellular Immune Responses	81	(18)
H. Golding
M. B. Zaitseva
C. K. Lapham
B. Golding
The Potential Use of Different Vaccination Protocols to Tailor Cytokine Profiles	99	(12)
Emmanuel Comoy
Andre Capron
Georges Thyphronitis
Modulation of Cytokine Responses by Iscoms and Iscom-Matrix	111	(8)
Maria Villacres-Eriksson
Shahriar Behboudi
Karin Lovgren-Bengtsson
Bror Morein
Vaccines and Vaccine Delivery Systems: Experience with HSV, Influenza and Mucosal Routes of Immunisation	119	(10)
R. Jennings
D. Ni Challanain
H. O. Ghazi
C. S. McLean
Active Immunotherapy for Solid Tumours	129	(18)
A. Maraveyas
A. G. Dalgleish
ISCOMS as Mucosal Vaccine Vectors	147	(8)
Allan McI. Mowat
Kevin J. Maloy
Rosemary E. Smith
Anne M. Donachie
Adjuvant Directed Immune Specificity at the Epitope Level: Implications for Vaccine Development. A Model Study Using Semliki Forest Virus Infection of Mice	155	(12)
H. Snippe
I. M. Fernandez
C. A. Kraaijeveld
Interleukin 1 and Its Synthetic Peptide 163-171 as Vaccine A'djuvants	167	(8)
Aldo Tagliabue
Diana Boraschi
The Immunological Co-Adjuvant Action of Liposomal Interleukin-15	175	(6)
Mayda Gursel
Gregory Gregoriadis
Protection against Tuberculosis by Plasmid DNA	181	(6)
R. E. Tascon
M. J. Colston
E. Stavropoulos
S. Ragno
D. Gregory
D. B. Lowrie
From Scientific Discovery to Clinical Trial: Overcoming the Regulatory Hurdles--A Guide for Academic Researchers	187	(10)
Jillian K. Bennet
Participants' Photograph	197	(2)
Contributors	199	(4)
Index	203