Well-Controlled Diet Studies in Humans : A Practical Guide to Design and Management

by Dennis, Barbara

• ISBN13: 9780880911580
• ISBN10: 0880911581
• Edition: 1st
• Format: Hardcover
• Copyright: 1999-02-01
• Publisher: Academy of Nutrition and Dietetics

Summary

This comprehensive and practical volume reviews everything you need to know to design, implement, and manage human research studies. The 25 chapters are grouped into five sections: Study Design, Human Factors , The Dietary Intervention, The Research Kitchen, and Enhancing the Ou tcomes of Dietary Studies. Comprehensive resources, including numerou s figures, tables, and bibliographies accompany each chapter.

Table of Contents

Foreword	p. viii
Acknowledgments	p. ix
Contributors	p. x
Introduction	p. xiii
Study Design
The Scientific Rationale of Human Feeding Studies	p. 2
Statistical Aspects of Controlled Diet Studies	p. 10
Computer Applications in Controlled Diet Studies	p. 19
Genetic Effects in Human Dietary Studies	p. 44
Human Factors
Ethical Considerations in Dietary Studies	p. 62
Recruitment and Screening of Study Participants	p. 76
Managing Participants and Maximizing Compliance	p. 96
Women as Participants in Controlled Diet Studies	p. 109
Children as Participants in Feeding Studies	p. 126
The Dietary Intervention
Planning Diet Studies	p. 142
Designing Research Diets	p. 155
Producing Research Diets	p. 179
Delivering Research Diets	p. 195
Planning and Producing Formula Diets	p. 212
Meeting Requirements for Fluids	p. 232
Compartmental Modeling, Stable Isotopes, and Balance Studies	p. 238
Energy Needs and Weight Maintenance in Controlled Feeding Studies	p. 255
The Research Kitchen
Documentation, Record Keeping, and Recipes	p. 264
Facilities and Equipment for the Research Kitchen	p. 290
Staffing Needs for Research Diet Studies	p. 299
Performance Improvement for the Research Kitchen	p. 323
Enhancing the Outcome of Dietary Studies
Validating Diet Composition by Chemical Analysis	p. 336
Laboratory Quality Control in Dietary Trials	p. 368
Biological Sample Collection and Biological Markers of Dietary Compliance	p. 379
The Multicenter Approach to Human Feeding Studies	p. 390
Index	p. 404
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